IP Library Granted Patent US 10,537,401
Granted Patent B2
US 10,537,401 · App. 15/793,555 · Granted Jan 21, 2020

Vitreous visualization system and method

Inventors: Cesario Dos Santos (Newport Beach, CA); Andrew David Johnson (Laguna Niguel, CA); Ronald Smith (Irvine, CA); Gerald David Bacher (Carlsbad, CA); Alireza Mirsepassi (Irvine, CA); Ryan Takakawa (Aliso Viejo, CA)
Assignee: Novartis AG
A61B90/30A61B90/20A61B3/0008A61B3/132A61B90/37A61B2090/306A61B2090/309A61F9/00736
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Quick Facts
Patent No.
US 10,537,401
App. No.
15/793,555
Granted
Jan 21, 2020
Kind
B2
Abstract

The present disclosure provides a vitreous visualization system including a vitreous illuminator including a vitreous visualization light source and a vitreous visualization tool that transmits lights from the vitreous visualization light source into an eye having vitreous, a pupil, and a vitreous-pupil axis. The vitreous visualization system further includes a general illuminator, which may include a general light source and a general illumination tool that transmits light from the general light source into the eye. The present disclosure further provided a vitreous visualization system including only a vitreous illuminator that transmits light from the vitreous visualization light source into an eye having vitreous, a pupil, a vitreous-pupil axis, and a retina at an angle B with the vitreous-pupil axis of the eye such that the brightness of vitreous in the eye is higher than the brightness of the retina of the eye.

Claims (39)

1. A vitreous visualization system comprising:

a vitreous illuminator comprising:

a vitreous visualization light source; and

a vitreous visualization tool that is configured to transmit light from the vitreous visualization light source into an eye having vitreous, a pupil, and a vitreous-pupil axis;

a general illuminator comprising:

a general light source; and

a general illumination tool that is configured to transmit light from the general light source into the eye;

wherein the vitreous visualization tool and the general illumination tool form a combined tool;

wherein the combined tool comprises a multi-core optical fiber having a core optical fiber that transmits light from the vitreous visualization light source and an exterior optical fiber that transmits light from the general light source.

2. The vitreous visualization system of claim 1 , further comprising a vitreous conduit that transmits light from the vitreous visualization light source to the vitreous visualization tool.

3. The vitreous visualization system of claim 1 , wherein the vitreous visualization light source is located within the vitreous visualization tool.

4. The vitreous visualization system of claim 1 , wherein the vitreous visualization light source generates light at a wavelength corresponding to a visible color and the general light source generates white light.

5. The vitreous visualization system of claim 1 , wherein the vitreous visualization light tool is configured to transmit light into the eye at an angle of illumination A that is less than 45 degrees.

6. The vitreous visualization system of claim 1 , wherein the vitreous visualization tool has a numeric aperture of less than 0.30.

7. The vitreous visualization system of claim 1 , wherein the general illumination tool is configured to transmit light into the eye at an angle of illumination C, which is less than 75 degrees.

8. The vitreous visualization system of claim 1 , wherein a luminous flux of the vitreous illuminator, as measured at a tip of the vitreous visualization tool, is at least five times higher than a luminous flux of the general illuminator, as measured at a tip of the general illumination tool.

9. The vitreous visualization system of claim 1 , wherein the vitreous visualization tool is configured to transmit light into the eye at an angle of illumination A, and wherein an angle B formed between a center of angle of illumination A and the vitreous-pupil axis is less than 100 degrees.

10. The vitreous visualization system of claim 1 , wherein the general illumination tool is configured to transmit light into the eye at an angle of illumination C, and wherein an angle D formed between a center of angle of illumination D and the vitreous-pupil axis is at least 90 degrees.

11. The vitreous visualization system of claim 10 , wherein the vitreous visualization tool is configured to transmit light into the eye at an angle of illumination A, and wherein an angle B formed between a center of angle of illumination A and the vitreous-pupil axis is less than 100 degrees.

12. The vitreous visualization system of claim 1 , wherein the vitreous illuminator generates pulses of light.

13. The vitreous visualization system of claim 1 , wherein the vitreous visualization tool is configured to have a luminous flux at its tip within the eye of 10 lumens or less.

14. The vitreous visualization system of claim 1 , wherein a distance between the vitreous visualization light source and the vitreous is configured to be less than three meters.

15. The vitreous visualization system of claim 1 , wherein the vitreous visualization tool is combined with a surgical tool.

16. The vitreous visualization system of claim 1 , wherein the vitreous visualization light source and the general light source are a single combined light source.

17. The vitreous visualization system of claim 1 , wherein the vitreous visualization light source is a monochromatic laser and the general light source is a white light source.

18. The vitreous visualization system of claim 1 , wherein the vitreous visualization light source is a monochromatic laser and the general light source is a supercontinuum laser.

19. A vitreous visualization system comprising a vitreous illuminator comprising:

a vitreous visualization light source; and

a vitreous visualization tool that is configured to transmit light from the vitreous visualization light source into an eye having vitreous, a pupil, a vitreous-pupil axis, and a retina at an angle B with the vitreous-pupil axis of the eye such that a brightness of the vitreous in the eye is higher than a brightness of the retina of the eye;

a general illuminator comprising:

a general light source; and

a general illumination tool that is configured to transmit light from the general light source into the eye;

wherein the vitreous visualization tool and the general illumination tool form a combined tool;

wherein the combined tool comprises a single optical fiber that transmits both the light from the vitreous visualization light source and the light from the general light source;

wherein the vitreous visualization light source is a monochromatic laser and the general light source is a white light source and wherein a dichroic filter combines the laser light from the vitreous visualization light source and the white light from the white light source to form a collimated beam to place on the single optical fiber of the combined tool.

20. The vitreous visualization system of claim 19 , further comprising a vitreous conduit that transmits light from the vitreous visualization light source to the vitreous visualization tool.

21. The vitreous visualization system of claim 19 , wherein the vitreous visualization light source is located within the vitreous visualization tool.

22. The vitreous visualization system of claim 19 , wherein the vitreous visualization light tool transmits light into the eye at an angle of illumination A that is less than 45 degrees.

23. The vitreous visualization system of claim 19 , wherein the vitreous visualization tool has a numeric aperture of less than 0.30.

Assignments (3)
CONFIRMATORY DEED OF ASSIGNMENT EFFECTIVE APRIL 8, 2019 Recorded Dec 10, 2019
From: NOVARTIS AG
To: ALCON INC.
Reel/Frame 051454/0788 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 22, 2018
From: SANTOS, CESARIO DOS; JOHNSON, ANDREW DAVID; SMITH, RONALD; BACHER, GERALD DAVID; MIRSEPASSI, ALIREZA; TAKAKAWA, RYAN
To: ALCON RESEARCH, LTD.
Reel/Frame 044688/0495 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 22, 2018
From: ALCON RESEARCH, LTD.
To: NOVARTIS AG
Reel/Frame 044688/0884 →
Continuity (2)
Provisional Application 62424893 · Nov 21, 2016
Related Publication 20180140373A1 · May 24, 2018
Cited By (2)
US 12,208,036 US 12,376,937