Biosensor system, sensor chip, and method of measuring analyte concentration in blood sample

1. A biosensor system, comprising:

a measuring instrument having an operation part; and

a sensor chip that is insertable into and removable from the measuring instrument, and comprises:

a capillary part that holds a blood sample introduced into the sensor chip;

a measurement part A including an electrode A and an electrode B in the capillary part;

a measurement part B including the electrode A and an electrode C in the capillary part;

a reaction reagent layer formed on the electrodes A and B but not on the electrode C; and

a spacer formed on the reaction reagent layer, wherein

the operation part has a conversion table established using a relationship where the amount of electric current that flows in a blood sample due to the reaction involving the oxidoreductase with the analyte used as a substrate varies in the same manner as the amount of electric current that flows in a blood sample according to oxidation or reduction of a redox substance other than the analyte, when the temperature of the blood sample varies,

the measurement part A acquires Data a related to a concentration of an analyte in the blood sample based on the amount of electric current that flows in the blood sample due to a reaction in which an oxidoreductase with the analyte used as a substrate is involved;

the measurement part B acquires Data b suitable for temperature correction of the Data a, and

the operation part is configured to determine the concentration of the analyte in the blood sample based on the Data a, as corrected based on the Data b measured by measurement part B, thereby avoiding the influence of the temperature of the blood sample in the measurement of the analyte concentration with reference to the conversion table.

2. The biosensor system according to claim 1 , wherein the electrodes A, B and C are formed of conductive materials selected from the group consisting of palladium, platinum, gold, silver, titanium, copper, nickel and carbon.

3. The biosensor system according to claim 1 , wherein the spacer has the capillary part, and a height of the capillary part is 0.05 mm to 0.3 mm.

4. The biosensor system according to claim 1 , wherein the measuring instrument has a control circuit that provides the measurement part A with a signal that indicates acquisition of the Data a within a range of at least 0.5 second but less than 2.5 seconds from the time when the blood sample has been introduced into the sensor chip.

5. The biosensor system according to claim 1 , wherein the reaction reagent layer contains the oxidoreductase,

the reaction reagent layer contains no water-soluble polymer or contains less than 0.2 mass % of water-soluble polymer, and

the measuring instrument has a control circuit that provides the measurement part A with a signal that indicates acquisition of the Data a within a range of at least 0.5 second but less than 2.5 seconds from the time when the blood sample has been introduced into the sensor chip.

6. The biosensor system according to claim 1 , wherein the reaction reagent layer contains the oxidoreductase,

the reaction reagent layer contains at least 0.2 mass % of water-soluble polymer, and

the measuring instrument has a control circuit that provides the measurement part A with a signal that indicates acquisition of the Data a after a lapse of at least 2.5 seconds from the time when the blood sample has been introduced into the sensor chip.

7. The biosensor system according to claim 1 , wherein the electrode A is a working electrode for the measurement part A and a counter electrode for the measurement part B.