Apparatus and methods for delivering therapeutic agents
View Patent ↗The present embodiments provide apparatus and methods suitable for delivering a therapeutic agent to a target site. The apparatus generally comprises at least one container for holding a therapeutic agent, and a pressure source for facilitating delivery of the therapeutic agent. In one embodiment, the pressure source may be placed in selective fluid communication with a proximal region of the container and fluid from the pressure source may flow through at least a portion of the container to urge the therapeutic agent through container towards the target site. In an alternative embodiment, the container and the pressure source may be coupled to first and second inlet ports of a connecting member, respectively, such that the therapeutic agent flows through an outlet port of the connecting member and towards the target site.
1. A method suitable for delivering at least one therapeutic agent to a target site, the method comprising:
providing at least one container having proximal and distal regions, wherein the container holds a therapeutic agent;
placing a pressure source in selective fluid communication with the proximal region of the container;
actuating the pressure source to cause fluid to flow through at least a portion of the container to both a) generate a mixture of fluid from the pressure source and the therapeutic agent and b) urge the mixture of the fluid from the pressure source and the therapeutic agent concurrently through the distal region of the container and then through a tube member in a distal direction towards the target site; and
selectively inhibiting flow of the mixture of the fluid from the pressure source and the therapeutic agent using a valve having a proximal end and a distal end, wherein the proximal end and the distal end of the valve are disposed distal to the container and proximal to the tube member.
2. The method of claim 1 , wherein the therapeutic agent comprises a powder.
3. The method of claim 1 , wherein the pressure source comprises a compressed gas dispenser.
4. The method of claim 1 , further comprising placing a tube between the pressure source and the container.
5. The method of claim 1 , further comprising placing a pressure relief valve between the pressure source and the container.
6. A method suitable for delivering at least one therapeutic agent to a target site, the method comprising:
positioning a distal end of a tube member adjacent to a target site, wherein a proximal end of the tube member is coupled to a distal region of a container holding a therapeutic agent;
actuating a pressure source to cause fluid to flow through a proximal region of the container to both a) generate a mixture of the fluid from the pressure source and the therapeutic agent and b) urge the mixture of the fluid from the pressure source and the therapeutic agent to flow concurrently through the distal region of the container and then through the tube member in a distal direction towards the target site; and
selectively inhibiting flow of the mixture of the fluid from the pressure source and the therapeutic agent using a valve having a proximal end and a distal end, wherein the proximal end and the distal end of the valve are disposed distal to the container and proximal to the tube member.
7. The method of claim 6 , wherein the therapeutic agent comprises a powder.
8. The method of claim 6 , wherein the pressure source comprises a compressed gas dispenser.
9. The method of claim 6 further comprising:
providing tubing disposed between the pressure source and the container; and
providing a pressure relief valve disposed between the pressure source and the container.
10. A method suitable for delivering at least one therapeutic agent to a target site, the method comprising:
placing a pressure source in selective fluid communication with a proximal region of a container, wherein the container holds a therapeutic agent;
positioning a distal end of a tube member adjacent to a target site, wherein a proximal end of the tube member is coupled to a distal region of the container;
actuating the pressure source to cause fluid to flow through at least a portion of the container to both a) generate a mixture of fluid from the pressure source and the therapeutic agent and b) urge the mixture from the pressure source and the therapeutic agent concurrently through the distal region of the container and then through the tube member in a distal direction towards the target site;
wherein the therapeutic agent comprises a powder; and
wherein the pressure source comprises a compressed gas dispenser.
11. The method of claim 10 , further comprising selectively inhibiting flow of the mixture of the fluid from the pressure source and the therapeutic agent using a valve disposed proximal to the tube member.
12. The method of claim 10 , further comprising placing a tube between the pressure source and the container.
13. The method of claim 10 , further comprising placing a pressure relief valve between the pressure source and the container.