IP Library Granted Patent US 10,248,882
Granted Patent B2
US 10,248,882 · App. 15/804,915 · Granted Apr 2, 2019

Matching geometry generation and display of mammograms and tomosynthesis images

Inventors: Baorui Ren (Andover, MA); Christopher Ruth (Boxford, MA); Andrew P. Smith (Lexington, MA); Kevin Wilson (Waltham, MA); Jay A. Stein (Boston, MA)
Assignee: Hologic, Inc.
G06K9/6201A61B6/502G06T3/0006G06T7/30G06T11/006G06T11/60G06T2207/10081G06T2207/30068
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Quick Facts
Patent No.
US 10,248,882
App. No.
15/804,915
Granted
Apr 2, 2019
Kind
B2
Abstract

A method and a system for using tomosynthesis projection images of a patient's breast to reconstruct slice tomosynthesis images such that anatomical structures that appear superimposed in a mammogram are at conforming locations in the reconstructed images.

Claims (34)

1. A method comprising:

imaging a breast so as to acquire digital information corresponding to a plurality of x-ray tomosynthesis projection images of the breast taken at different angles;

generating, from the digital information, a plurality of reconstructed tomosynthesis images representative of respective breast layers;

obtaining a mammogram image of the breast;

receiving a selection of a region of interest in the mammogram image of the breast; and

displaying a portion of at least one of the plurality of reconstructed tomosynthesis images corresponding to the selected region of interest.

2. The method of claim 1 , further comprising displaying a portion of the mammogram image of the breast.

3. The method of claim 2 , further comprising simultaneously:

displaying the portion of the mammogram image; and

displaying the portion of the at least one of the plurality of reconstructed tomosynthesis images.

4. The method of claim 3 , wherein the portion of the at least one of the plurality of reconstructed tomosynthesis images is displayed within the selected region of interest.

5. The method of claim 4 , further comprising:

receiving an input; and

in response to the received input, displaying sequentially at least a portion of each of at least two of the plurality of reconstructed tomosynthesis images.

6. The method of claim 5 , wherein the at least a portion of each of at least two of the plurality of reconstructed tomosynthesis images are displayed within the selected region of interest.

7. The method of claim 1 , wherein each of the plurality of reconstructed tomosynthesis images are parallel to an image plane of the mammogram image of the breast.

8. The method of claim 1 , wherein the obtaining operation comprises directing an x-ray at the breast.

9. The method of claim 1 , wherein each of the plurality of reconstructed tomosynthesis images is representative of respective breast layers and has a layer thickness corresponding to a thickness of a breast that is less than a total thickness of the breast.

10. The method of claim 1 , wherein the selection of the region of interest comprises a drawing of a region of interest.

11. A method comprising:

displaying a mammogram image of a compressed breast, wherein the mammogram image corresponds to substantially an entire thickness of the compressed breast;

receiving an input corresponding to a region of interest in the mammogram image;

displaying, within the region of interest, at least a portion of a first reconstructed tomosynthesis image, wherein the first reconstructed tomosynthesis image corresponds to less than substantially the entire thickness of the compressed breast.

12. The method of claim 11 , further comprising displaying at least a portion of the mammogram image.

13. The method of claim 12 , wherein the a portion of the mammogram image within the region of interest is not displayed.

14. The method of claim 13 , further comprising receiving an input and, based at least in part on the input, displaying sequentially the portion of first reconstructed tomosynthesis image and a portion of a second reconstructed tomosynthesis image.

15. The method of claim 14 , further comprising:

receiving a marker input when the first reconstructed tomosynthesis image is displayed; and

displaying the marker on the first reconstructed tomosynthesis image.

16. The method of claim 15 , further comprising displaying the marker on the second reconstructed tomosynthesis image.

17. The method of claim 15 , wherein the marker corresponds to a location of a suspected abnormality.

18. The method of claim 11 , wherein the first reconstructed tomosynthesis image corresponds to a first reconstructed tomosynthesis image plane that is substantially parallel to a mammogram image plane.

19. The method of claim 11 , further comprising obtaining the mammogram image and the first reconstructed tomosynthesis image.

20. The method of claim 19 , wherein at least one of the mammogram image and the first reconstructed tomosynthesis image is obtained by directing x-rays at the compressed breast.

Assignments (3)
SECURITY INTEREST Recorded Apr 8, 2026
From: BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; CYTYC CORPORATION; SUROS SURGICAL SYSTEMS, INC.; GYNESONICS, INC.; BOLDER SURGICAL, LLC; FAXITRON BIOPTICS, LLC; HEALTH BEACONS, INC.; HOLOGIC, INC.
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 075462/0440 →
SECURITY INTEREST Recorded Oct 14, 2019
From: HOLOGIC, INC.; CYNOSURE, LLC; CYTYC CORPORATION; FAXITRON BIOPTICS, LLC; FOCAL THERAPEUTICS, INC.; GEN-PROBE INCORPORATED
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 050719/0701 →
SECURITY INTEREST Recorded Oct 19, 2018
From: HOLOGIC, INC.; GEN-PROBE INCORPORATED; CYNOSURE, INC.; FAXITRON BIOPTICS, LLC
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 047272/0347 →
Continuity (7)
Continuation 14744930 · Jun 19, 2015
Continuation 14263216 · Apr 28, 2014
Continuation 13418851 · Mar 13, 2012
Continuation 12535343 · Aug 4, 2009
Continuation 11667650
Provisional Application 60628516 · Nov 15, 2004
Related Publication 20180137385A1 · May 17, 2018
Cited By (4)
US 12,186,119 US 12,191,027 US 12,207,963 US 12,367,574