IP Library Granted Patent US 10,526,356
Granted Patent B2
US 10,526,356 · App. 15/805,401 · Granted Jan 7, 2020

Bisphosphites having 2,4-tert-butylphenyl units and use thereof as ligands in hydroformylation

Inventors: Katrin Marie Dyballa (Recklinghausen, DE); Robert Franke (Marl, DE); Dirk Fridag (Haltern am See, DE); Dieter Hess (Marl, DE)
Assignee: EVONIK DEGUSSA GMBH
C07F9/141B01J31/185C07C45/50C07C45/505C07F9/145C07F15/008C07F15/0073B01J2231/321B01J2531/822
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Quick Facts
Patent No.
US 10,526,356
App. No.
15/805,401
Granted
Jan 7, 2020
Kind
B2
Abstract

The invention relates to bisphosphites having 2,4-tert-butylphenyl units and a method for the preparation thereof. Furthermore, the invention relates to the use of the compounds as ligands in a ligand-metal complex. The compound, and also the complex, may be used as a catalytically active composition in hydroformylation reactions.

Claims (45)

1. A compound of the formula (I):

where

R 1 , R 3 , R 4 are selected from the group consisting of: —H, —(C 1 -C 12 )-alkyl and —O—(C 1 -C 12 )-alkyl, and

R 2 is —O—(C1-C12)-alkyl,

wherein the alkyl groups mentioned may be substituted as follows:

substituted —(C 1 -C 12 )-alkyl groups and substituted —(C 1 -C 12 )-alkoxy groups, depending on their chain length, may have one or more substituents; the substituents are mutually independently selected from —(C 3 -C 12 )-cycloalkyl, —(C 3 -C 12 )-heterocycloalkyl, —(C 6 -C 20 )-aryl, fluorine, chlorine, cyano, formyl, acyl or alkoxycarbonyl;

and at least one of the R 1 , R 3 and R 4 radicals is not —H.

2. The compound according to claim 1 ,

where R 4 is not —H.

3. The compound according to claim 1 ,

where R 4 is —(C 1 -C 12 )-alkyl or —O—(C 1 -C 12 )-alkyl.

4. The compound according to claim 1 ,

where R 4 is —(C 1 -C 12 )-alkyl.

5. The compound according to claim 1 ,

where R 2 is —OMe.

6. The compound according to claim 1 ,

where R 4 is -Me or -tBu.

7. The compound according to claim 1 ,

where R 4 is -tBu.

8. The compound according to claim 1 ,

according to the formula (1):

9. A process comprising the following process steps:

a) initially charging an olefin, forming a reaction mixture,

b) adding a compound according to claim 1 and a substance including a metal selected from: Rh, Ru, Co or Ir,

c) feeding in H 2 and CO,

d) heating the reaction mixture, wherein the olefin is converted to an aldehyde.

10. A complex according to the formula (II):

where

R 1 , R 2 , R 3 and R 4 are —H, —(C 1 -C 12 )-alkyl or —O—(C 1 -C 2 )-alkyl,

wherein the alkyl groups mentioned may be substituted as follows:

substituted —(C 1 -C 12 )-alkyl groups and substituted —(C 1 -C 12 )-alkoxy groups, depending on their chain length, may have one or more substituents; the substituents are mutually independently selected from —(C 3 -C 12 )-cycloalkyl, —(C 3 -C 12 )-heterocycloalkyl, —(C 6 -C 20 )-aryl, fluorine, chlorine, cyano, formyl, acyl or alkoxycarbonyl;

and M is Rh, Ru, Co or Ir.

11. The complex according to the formula (III):

where

R 1 , R 2 , R 3 or R 4 are —H, —(C 1 -C 12 )-alkyl or —O—(C 1 -C 12 )-alkyl,

wherein the alkyl groups mentioned may be substituted as follows:

substituted —(C 1 -C 12 )-alkyl groups and substituted —(C 1 -C 12 )-alkoxy groups, depending on their chain length, may have one or more substituents; the substituents are mutually independently selected from —(C 3 -C 12 )-cycloalkyl, —(C 3 -C 12 )-heterocycloalkyl, —(C 6 -C 20 )-aryl, fluorine, chlorine, cyano, formyl, acyl or alkoxycarbonyl;

and M is Rh, Ru, Co or Ir.

12. The complex according to claim 10 ,

where M is Rh.

13. A process comprising the following process steps:

a) initially charging an olefin, forming a reaction mixture,

b) adding a complex according to claim 10 ,

c) feeding in H 2 and CO,

d) heating the reaction mixture, wherein the olefin is converted to an aldehyde.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 9, 2024
From: EVONIK OPERATIONS GMBH
To: EVONIK OXENO GMBH & CO. KG
Reel/Frame 066242/0585 →
CHANGE OF NAME Recorded Mar 29, 2020
From: EVONIK DEGUSSA GMBH
To: EVONIK OPERATIONS GMBH
Reel/Frame 052254/0052 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 7, 2018
From: DYBALLA, KATRIN MARIE; FRANKE, ROBERT; FRIDAG, DIRK; HESS, DIETER
To: EVONIK DEGUSSA GMBH
Reel/Frame 046016/0896 →
Priority Claims (1)
EP 16197715 · Nov 8, 2016 · regional
Continuity (1)
Related Publication 20180127444A1 · May 10, 2018
Cited By (1)
US 12,595,339