IP Library Granted Patent US 10,322,289
Granted Patent B2
US 10,322,289 · App. 15/816,105 · Granted Jun 18, 2019

Wireless midfield systems and methods

Inventors: Ada Shuk Yan Poon (Redwood City, CA); Alexander Yeh (Los Altos Hills, CA); Yuji Tanabe (Cupertino, CA); John Ho (Palo Alto, CA); Sanghoek Kim (Palo Alto, CA)
Assignee: The Board of Trustees of the Leland Stanford Junior University
A61N1/3787A61B5/0008A61B5/0013A61B5/0031A61B5/0084A61B5/01A61B5/026A61B5/0215A61B5/04A61B5/14503A61B5/14539A61B5/14542A61B5/686A61H1/008A61H23/004A61M5/14276A61M31/002A61N1/056A61N1/0534A61N1/0551A61N1/3601A61N1/362A61N1/3605A61N1/365A61N1/36125A61N1/36139A61N1/3756A61N1/37211A61N1/37229A61N5/0601A61N7/00H02J7/025H02J50/10H02J50/20A61B2560/0219A61H2201/1207A61M2205/8206H01Q1/273H01Q9/0407H02J50/23
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Quick Facts
Patent No.
US 10,322,289
App. No.
15/816,105
Granted
Jun 18, 2019
Kind
B2
Abstract

Implantable devices and/or sensors can be wirelessly powered by controlling and propagating electromagnetic waves in a patient's tissue. Such implantable devices/sensors can be implanted at target locations in a patient, to stimulate areas such as the heart, brain, spinal cord, or muscle tissue, and/or to sense biological, physiological, chemical attributes of the blood, tissue, and other patient parameters. The propagating electromagnetic waves can be generated with sub-wavelength structures configured to manipulate evanescent fields outside of tissue to generate the propagating waves inside the tissue. Methods of use are also described.

Claims (33)

1. A method for using a mid-field system to temporarily sense a physiologic signal from a patient or to temporarily provide an electrostimulation therapy to the patient, the method comprising:

providing a mid-field receiver device at a target location in a patient body, the receiver device including an antenna configured to receive a wireless mid-field power signal from an external mid-field transmitter, and the receiver device further including at least one of a physiologic sensor configured to sense a physiologic signal from the target location or an electrode configured to provide an electrostimulation therapy at the target location;

transmitting a mid-field power signal using the mid-field transmitter, including manipulating evanescent fields outside of the patient body and thereby generating electromagnetic waves propagating inside the patient body;

receiving at least a portion of the mid-field power signal from the mid-field transmitter using the mid-field receiver device; and

in response to receiving the portion of the mid-field power signal, at least one of:

providing a temporary electrostimulation therapy to the target location using the electrode and a portion of the received mid-field power signal, and

sensing a physiologic signal from the target location using the physiologic sensor wherein the physiologic sensor is powered by the received mid-field power signal.

2. The method of claim 1 , wherein the sensing the physiologic signal from the target location includes sensing an evoked physiologic response.

3. The method of claim 1 , wherein the providing the mid-field receiver device at the target location includes delivering the mid-field receiver device using a catheter to position the mid-field receiver device within a targeted nerve or muscle region.

4. The method of claim 1 , wherein the providing the mid-field receiver device at the target location includes injecting the mid-field receiver device in a targeted nerve or muscle region.

5. The method of claim 1 , wherein the providing the mid-field receiver device at the target location includes providing a mid-field receiver device that does not include a physical lead configured to couple the receiver device to an external impulse generator.

6. The method of claim 1 , further comprising sensing the physiologic signal from the target location using the physiologic sensor; and

based on the sensed patient parameter, determining an efficacy of a temporary therapy provided to the patient.

7. The method of claim 1 , wherein the providing the mid-field receiver device at the target location in the patient body includes providing a mid-field receiver device at a neural target, wherein the mid-field receiver device is configured to deliver a temporary therapy to the neural tissue target.

8. The method of claim 1 , wherein the providing the mid-field receiver device at the target location in the patient body includes providing a mid-field receiver device at or in a muscle tissue target, wherein the mid-field receiver device is configured to deliver a temporary therapy to the muscle tissue target.

9. The method of claim 1 , wherein the providing the mid-field receiver device at the target location in the patient body includes providing a mid-field receiver device in or near a brain tissue target, wherein the mid-field receiver device is configured to deliver a temporary therapy to a brain tissue target.

10. The method of claim 1 , wherein the transmitting the mid-field power signal includes providing an excitation signal to at least one sub-wavelength structure in the external mid-field transmitter to thereby generate the mid-field power signal using the at least one sub-wavelength structure.

11. The method of claim 1 , wherein the transmitting the mid-field power signal includes transmitting a signal in a frequency range from about 300 MHz to about 3 GHz.

12. A method for providing a temporary treatment to an internal body tissue target using a mid-field receiver device, the method comprising:

receiving a wireless mid-field power signal at a mid-field receiver device that is implanted in a patient body, the power signal received from an external mid-field transmitter, wherein the wireless mid-field power signal comprises a portion of a propagating signal inside the patient body;

in response to receiving the wireless mid-field power signal at the mid-field receiver device, generating an electrostimulation therapy signal using a signal generator in the mid-field receiver device; and

providing the generated electrostimulation therapy signal to the tissue target using an electrode coupled to the mid-field receiver device.

13. The method of claim 12 , wherein the receiving the wireless mid-field power signal includes receiving a portion of a signal originated outside of the patient body and having a frequency at origination between about 300 MHz and about 3 GHz.

14. The method of claim 12 , further comprising providing an excitation signal to at least one sub-wavelength structure in an external mid-field transmitter and thereby generating the wireless mid-field power signal using the at least one sub-wavelength structure to manipulate evanescent fields outside of the patient body and generate the propagating signal inside the patient body.

15. The method of claim 12 , further comprising:

in response to receiving the wireless mid-field power signal at the mid-field receiver device, sensing a patient parameter using a physiologic sensor that is coupled to the implanted mid-field receiver device and that is powered by the received wireless mid-field power signal.

16. The method of claim 15 , further comprising determining an efficacy of a temporary treatment, provided to the tissue target by the mid-field receiver device, based on the sensed patient parameter.

17. A system configured to provide a temporary electrostimulation therapy to a patient using an implanted device, the system comprising:

an external mid-field transmitter configured to generate a mid-field power signal using at least one sub-wavelength structure to manipulate evanescent fields outside of the patient body and generate electromagnetic waves propagating inside the patient body; and

a mid-field receiver device, implanted at a target location inside the patient body, wherein the mid-field receiver device includes an antenna configured to receive the mid-field power signal from the external mid-field transmitter, and wherein the mid-field receiver device further includes at least one of a physiologic sensor configured to sense a physiologic parameter from the patient body or an electrode configured to provide a temporary electrostimulation therapy to a target inside the patient body.

18. The system of claim 17 , further comprising a catheter configured to carry the mid-field receiver device from outside the patient body to an implant location inside the patient body at a tissue target.

19. The system of claim 17 , wherein the external mid-field transmitter is configured to generate the mid-field power signal as an electromagnetic signal having a frequency between about 300 MHz and about 3 GHz.

20. The system of claim 17 , wherein the mid-field receiver device is a leadless device configured to receive operating power exclusively from the external mid-field transmitter.

Assignments (2)
SECURITY INTEREST Recorded May 18, 2026
From: NEUSPERA MEDICAL INC.
To: FIRST-CITIZENS BANK & TRUST COMPANY
Reel/Frame 075589/0305 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 23, 2020
From: POON, ADA SHUK YAN; YEH, ALEXANDER JUESHYAN; TANABE, YUJI; HO, JOHN; KIM, SANGHOEK
To: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Reel/Frame 054446/0140 →
Continuity (5)
Continuation 15605222 · May 25, 2017
Continuation 15022374
Provisional Application 61878436 · Sep 16, 2013
Provisional Application 61913164 · Dec 6, 2013
Related Publication 20180229044A1 · Aug 16, 2018
Cited By (1)
US 12,369,992