IP Library Granted Patent US 12,097,027
Granted Patent B2
US 12,097,027 · App. 15/818,173 · Granted Sep 24, 2024

Systems and methods for sample collection with reduced hemolysis

Inventors: Gregory J. Bullington (Seattle, WA); Richard G. Patton (Seattle, WA); Shan E. Gaw (Seattle, WA); Jay M. Miazga (Langley, WA); Jed McCann (Seattle, WA); Paul Goldenbaum (San Antonio, TX)
Assignee: Magnolia Medical Technologies, Inc.
A61B5/150206A61B5/15003A61B5/150099A61B5/150221A61B5/150236A61B5/150244A61B5/150251A61B5/150351A61B5/150396A61B5/150519A61B5/150572A61B5/150732A61B5/15074A61B5/150946A61B5/153A61B5/154A61B5/155A61M5/162A61M5/178A61M5/48A61M39/0208A61M39/22B01L3/50825B01L3/563A61B5/150389A61M5/3286A61M25/005A61M25/065B01L2200/0689B01L2300/042B01L2300/044B01L2300/069B01L2300/0854B01L2400/0457B01L2400/0478B01L2400/049B01L2400/0616B01L2400/084
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Quick Facts
Patent No.
US 12,097,027
App. No.
15/818,173
Granted
Sep 24, 2024
Kind
B2
Abstract

A collection system configured to maintain the integrity of a bodily fluid sample has a proximal end portion, a distal end portion, and an inner surface defining a fluid flow path therethrough. The distal end portion is configured to be placed in fluid communication with a patient. The proximal end portion is configured to be placed in fluid communication with a fluid reservoir. The fluid flow path defined by the inner surface is associated with at least one flow characteristic configured to limit a stress within the flow of the bodily fluid between the distal end portion and the proximal end portion.

Claims (11)

1. A device for procuring a blood sample with reduced damage from a patient to reduce inaccurate results in testing of the blood sample, the device comprising:

a first adapter having a distal end portion and a proximal end portion, the distal end portion configured to be placed in fluid communication with the patient, the first adapter defining a first lumen extending between the proximal end portion and the distal end portion, the first lumen having a first diameter;

a second adapter having a distal end portion and a proximal end portion, the proximal end portion of the second adapter configured to be placed in fluid communication with a fluid reservoir, the second adapter defining a second lumen extending between the proximal end portion and the distal end portion of the second adapter, the second lumen having a second diameter; and

a third adapter having a distal end portion configured to be coupled to the proximal end portion of the first adapter and a proximal end portion configured to be coupled to the distal end portion of the second adapter, the third adapter defining a distal lumen having a distal diameter substantially equal to the first diameter and a proximal lumen having a proximal diameter substantially equal to the second diameter, the third adapter having a medial portion forming a plurality of chambers disposed between the distal end portion and the proximal end portion of the third adapter, the plurality of chambers collectively defining an inner volume in fluid communication with each of the distal lumen and the proximal lumen of the third adapter,

a cross-sectional area of the inner volume alternatingly increasing or decreasing between a smaller cross-sectional area associated with a position along a longitudinal centerline between adjacent chambers from the plurality of chambers and a larger cross-sectional area associated with a position along the longitudinal centerline substantially in the center of each chamber from the plurality of chambers, the plurality of chambers configured such that the cross-sectional area of the inner volume changes between the smaller cross-sectional area and the larger cross-sectional area with a continuous curvature,

the plurality of chambers including a proximal chamber having a first volume, a distal chamber having a second volume greater than the first volume, and a medial chamber between the proximal chamber and the distal chamber, the medial chamber having a third volume greater than the second volume, the plurality of chambers configured to facilitate a laminar flow of the blood sample through the inner volume of the third adapter, and

the first adapter, the second adapter, and the third adapter collectively defining a portion of a fluid flow path between the patient and the fluid reservoir when the third adapter is coupled between the first adapter and the second adapter, the plurality of chambers operable to reduce a negative pressure within a portion of the fluid flow path distal to the third adapter.

2. The device of claim 1 , wherein reducing the negative pressure within the portion of the fluid flow path distal to the third adapter is operable to reduce damage to at least a portion of the blood sample flowing through the fluid flow path distal to the third adapter, and

wherein the damage of at least the portion of the blood sample can produce inaccurate results in testing of the blood sample.

3. The device of claim 1 , wherein a diameter of the inner volume of the third adapter at the position along the longitudinal centerline substantially in the center of each chamber from the plurality of chambers is greater than each of the first diameter and the second diameter.

4. The device of claim 1 , wherein the plurality of chambers forms a set of semi-spherical portions of the third adapter.

Assignments (4)
PATENT SECURITY AGREEMENT Recorded Jan 2, 2024
From: MAGNOLIA MEDICAL TECHNOLOGIES, INC.
To: SYMBIOTIC CAPITAL AGENCY LLC, AS ADMINISTRATIVE AGENT
Reel/Frame 066178/0969 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 21, 2021
From: BULLINGTON, GREGORY J.; GAW, SHAN E.; PATTON, RICHARD G.; MIAZGA, JAY M.; GOLDENBAUM, PAUL; MCCANN, JED
To: MAGNOLIA MEDICAL TECHNOLOGIES, INC.
Reel/Frame 058442/0506 →
RELEASE OF SECURITY INTEREST Recorded Dec 14, 2021
From: FISH & RICHARDSON PC
To: MAGNOLIA MEDICAL TECHNOLOGIES, INC
Reel/Frame 058964/0845 →
LIEN Recorded Mar 30, 2021
From: MAGNOLIA MEDICAL TECHNOLOGIES, INC.
To: FISH & RICHARDSON P.C.
Reel/Frame 057204/0676 →
Continuity (2)
Provisional Application 62423993 · Nov 18, 2016
Related Publication 20180140240A1 · May 24, 2018