Reducing levels of nicotinic alkaloids in plants
View Patent ↗Two genes, A622 and NBB1, can be influenced to achieve a decrease of nicotinic alkaloid levels in plants. In particular, suppression of one or both of A622 and NBB1 may be used to decrease nicotine in tobacco plants.
1. A tobacco plant comprising plant cells into which one or more mutations are introduced into the region of SEQ ID NO: 3 that encodes a polypeptide having the amino acid sequence set forth in SEQ ID NO: 4, wherein the plant exhibits reduced expression of a gene product encoded by SEQ ID NO: 3 as compared to a control tobacco plant.
2. The tobacco plant of claim 1 , wherein the tobacco plant exhibits a reduced nicotine level as compared to a control tobacco plant.
3. Seeds from or a progeny plant of the tobacco plant of claim 1 , wherein the seeds or progeny plant comprise in their genomes the one or more mutations.
4. A product comprising the plant of claim 2 , and having a reduced level of nicotine as compared to a product produced from a control plant, wherein the product is selected from the group consisting of a tobacco product, food product, food ingredient, feed product, feed ingredient, nutritional supplement, and biofuel.
5. The tobacco product of claim 4 , wherein the product is selected from the group consisting of smoking cessation products, cigarettes, cigarette tobacco, cigars, cigar tobacco, snus, pipe tobacco, and chewing tobacco.