IP Library Granted Patent US 10,493,009
Granted Patent B2
US 10,493,009 · App. 15/840,874 · Granted Dec 3, 2019

Stable personal care compositions containing a retinoid

Inventors: Robert Bao Kim Ha (Liberty Township, OH); Joseph Harry Jansen (Harrison, OH); Mridula Manohar (Cincinnati, OH)
Assignee: The Procter & Gamble Company
A61K8/37A61K8/062A61K8/342A61K8/375A61K8/585A61K8/602A61K8/671A61K8/8152A61K8/891A61K8/91A61Q17/04A61Q19/00A61K2800/412A61K2800/52
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,493,009
App. No.
15/840,874
Granted
Dec 3, 2019
Kind
B2
Abstract

Personal care compositions that include a stable O/W emulsion, a stable retinoid, an oil, a fatty alcohol, and an emulsifier and methods of using such compositions to regulate a condition of mammalian keratinous tissue. By combining the oil and retinoid at a particular ratio in the personal care composition, the stability of the retinoid can be improved.

Claims (14)

1. A topical personal care composition having improved stability of retinyl propionate, comprising:

a) a dermatologically acceptable carrier in the form of an oil-in-water (O/W) emulsion;

b) retinyl propionate;

c) capric/caprylic triglyceride, wherein the weight ratio of capric/caprylic triglyceride to retinyl propionate is about 15:1 to about 35:1 when the composition is made;

d) an emulsifier, wherein the weight ratio of capric/caprylic triglyceride to emulsifier is about 4:1 to about 50:1;

e) a fatty alcohol, wherein the weight ratio of fatty alcohol to emulsifier is about 1:1: to about 11:1; and

f) wherein less than 15% of the retinyl propionate degrades according to the HPLC Method.

2. The composition of claim 1 , wherein the composition comprises about 0.0001% to about 2%, by weight of the composition, of the retinyl propionate.

3. The composition of claim 2 , wherein the composition comprises about 0.01% to about 1%, by weight of the composition, of the retinyl propionate.

4. The composition of claim 1 , wherein the retinyl propionate is present at about 0.1% to about 0.5%, by weight of the composition.

5. The composition of claim 1 , further comprising about 0.01% to about 5%, by weight of the composition, of a water-swellable material selected from the group consisting of clays and superabsorbent polymers.

6. The composition of claim 5 , wherein the water-swellable material is a superabsorbent polymer.

7. The composition of claim 6 , wherein the superabsorbent polymer has a dry, number-average particle size of about 2 μm to about 100 μm.

8. The composition of claim 1 , wherein the composition further comprises a skin care active selected from the group consisting of vitamins, proteins, zeolites, peptides, skin-lightening agents, sunscreen actives, terpene alcohols, desquamation actives, anti-acne actives, anti-wrinkle actives, anti-atrophy actives, anti-oxidants, flavanoids, anti-inflammatory agents, anti-cellulite agents, tanning actives, skin soothing actives, skin healing actives, conditioning agents, and combinations thereof.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 15, 2019
From: NEC LABORATORIES AMERICA, INC.
To: NEC CORPORATION
Reel/Frame 049750/0034 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 18, 2017
From: HA, ROBERT BAO KIM; JANSEN, JOSEPH HARRY; MANOHAR, MRIDULA NMN
To: THE PROCTER & GAMBLE COMPANY
Reel/Frame 044420/0642 →
Continuity (2)
Provisional Application 62433422 · Dec 13, 2016
Related Publication 20180161259A1 · Jun 14, 2018
Cited By (1)
US 12,582,593