IP Library Granted Patent US 10,231,908
Granted Patent B2
US 10,231,908 · App. 15/844,909 · Granted Mar 19, 2019

Method of reducing hair loss associated with chemotherapy

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Quick Facts
Patent No.
US 10,231,908
App. No.
15/844,909
Granted
Mar 19, 2019
Kind
B2
Abstract

A method of reducing hair loss (alopecia) in a patient undergoing or scheduled to undergo chemotherapy is claimed. The method involves administering brimonidine or a pharmaceutically acceptable salt thereof to the site of the hair follicles.

Claims (7)

1. A method of reducing hair loss in a patient undergoing chemotherapy, the method comprising topically applying a pharmaceutical composition comprising an effective amount of brimonidine or a pharmaceutically acceptable salt thereof to hair follicles with hair of the patient during the course of the chemotherapy.

2. The method according to claim 1 , wherein the brimonidine or a pharmaceutically acceptable salt thereof is brimonidine tartrate.

3. The method according to claim 1 , wherein the pharmaceutical composition is selected from the group consisting of a foam, conditioner, hair spray, shampoo, gel, cream, emulsion, and solution.

4. The method according to claim 3 , wherein the pharmaceutical composition is a foam, conditioner, or hair spray.

5. The method according to claim 1 , wherein the brimonidine or a pharmaceutically acceptable salt thereof is present in an amount of from about 0.05% by weight to about 5% by weight of the composition.

6. The method according to claim 1 , wherein the brimonidine or a pharmaceutically acceptable salt thereof is present in an amount of from about 0.05% by weight to about 2% by weight of the composition.

7. A method of reducing hair loss in a patient undergoing chemotherapy, the method comprising topically applying a pharmaceutical composition consisting of an effective amount of brimonidine or a pharmaceutically acceptable salt thereof and a pharmaceutical carrier to hair follicles with hair of the patient during the course of the chemotherapy.

Assignments (4)
CHANGE OF ADDRESS Recorded Jun 28, 2022
From: GALDERMA HOLDING SA
To: GALDERMA HOLDING SA
Reel/Frame 060541/0374 →
ASSET TRANSFER AGREEMENT Recorded Oct 3, 2021
From: GALDERMA S.A.
To: NESTLÉ SKIN HEALTH S.A.
Reel/Frame 057698/0295 →
CHANGE OF NAME Recorded Oct 3, 2021
From: NESTLÉ SKIN HEALTH S.A.
To: GALDERMA HOLDING SA
Reel/Frame 057698/0356 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 10, 2018
From: ANDRES, PHILIPPE
To: GALDERMA S.A.
Reel/Frame 044584/0818 →