IP Library Granted Patent US 11,331,463
Granted Patent B2
US 11,331,463 · App. 15/848,933 · Granted May 17, 2022

Infusion system and components thereof

Inventors: Edward R. Damiano (Acton, MA); Firas H. El-Khatib (Allston, MA); Rajendranath Selagamsetty (Boston, MA); Kirk D. Ramey (Tallahassee, FL)
Assignee: Trustees of Boston University
A61M39/105A61M5/142A61M5/1407A61M5/1408A61M5/14248A61M5/158A61M5/162A61M39/02A61M39/10A61M2005/1586A61M2039/1044A61M2039/1072A61M2039/1094A61M2205/43A61M2205/583A61M2205/584A61M2205/6018
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Quick Facts
Patent No.
US 11,331,463
App. No.
15/848,933
Granted
May 17, 2022
Kind
B2
Abstract

Certain embodiments provide multi-medicament infusion systems for preventing the cross-channeling of medicaments. The system may include one or more of an infusion pump, medicament reservoirs, collars, a multi-channel fluid conduit, and an infusion set. The medicament reservoirs and/or collars may be sized and shaped differently such that the medicament reservoirs can only be inserted into the system selected configurations.

Claims (57)

1. An infusion set for delivering a single or multiple medicaments to a patient, the infusion set comprising:

a base set comprising:

a first base unit having a first port and a first adhesive portion, the first base unit comprising a first piercing element configured to deliver a first medicament to the patient, the first adhesive portion configured to adhere the first base unit to the patient; and

a second base unit having a second port, the second base unit comprising a second adhesive portion configured to adhere the second base unit to the patient;

a connector set comprising:

a first distribution connector configured to reversibly couple to the first base unit via the first port and to provide a first fluid path from a first medicament reservoir to the first port of the first base; and

a second distribution connector configured to reversibly couple to the second base unit;

wherein the first base unit comprises a first guide member that prevents engagement of the second distribution connector to the first base unit;

wherein the second base unit comprises a second guide member that prevents engagement of the first distribution connector to the second base unit;

wherein the first base unit and the second base unit are able to move independently with respect to each other and are configured to fit contours of a body of the patient during movements made by the patient; and

wherein the second base unit comprises a second piercing element configured to deliver a second medicament to the patient, wherein the second distribution connector is configured to provide a second fluid path from a second medicament reservoir to the second port of the second base;

wherein the first distribution connector comprises a single retention clip that locks the first distribution connector in place when in a coupled position with the first base unit;

wherein the single retention clip is configured to be depressed to allow one-handed de-coupling of the first distribution connector from the first base unit; and

wherein the first distribution connector and second distribution connector are each asymmetric.

2. The infusion set of claim 1 , wherein the first piercing element is a catheter in fluidic communication with the first port and configured to deliver the first medicament to the patient via the first base unit.

3. The infusion set of claim 1 , wherein the second distribution connector comprises a single retention clip that locks the second distribution connector in place when in a coupled position with the second base unit, wherein the single retention clip of the first distribution connector is configured to prevent coupling of the first distribution connector to the second base unit and wherein the single retention clip of the second distribution connector is configured to prevent coupling of the second distribution connector to the first base unit.

4. The infusion set of claim 3 , wherein the single retention clip of the second distribution connector is configured to be depressed to allow one-handed de-coupling of the second distribution connector from the second port.

5. The infusion set of claim 1 , wherein the first distribution connector comprises an alignment feature that guides the first distribution connector in place when coupling it to the first base unit.

6. The infusion set of claim 1 , wherein the first and second piercing elements are flexible.

7. The infusion set of claim 1 , further comprising a first inlet connector and a first fluid conduit, the first fluid conduit being in fluidic communication with the first distribution connector;

wherein the first fluid path extends through the first inlet connector, the first fluid conduit, and the first distribution connector; and

wherein the first inlet connector is configured to engage the first medicament reservoir and to allow fluidic communication with the first medicament within the first medicament reservoir.

8. The infusion set of claim 7 , further comprising a second inlet connector and a second fluid conduit, the second fluid conduit being in fluidic communication with the second distribution connector;

wherein the second fluid path extends through the second inlet connector, the second fluid conduit, and the second distribution connector; and

wherein the second inlet connector is configured to engage the second medicament reservoir and to allow fluidic communication with the second medicament within the second medicament reservoir.

9. The infusion set of claim 8 , wherein the first inlet connector comprises engagement elements configured to engage a first receptacle of an infusion pump.

10. The infusion set of claim 9 , wherein the engagement features of the first inlet connector are configured to prevent engagement of the first inlet connector with a second receptacle of the infusion pump.

11. The infusion set of claim 10 , wherein the second inlet connector comprises engagement elements configured to engage a second receptacle of the infusion pump and wherein the engagement elements of the second inlet connector are configured to prevent engagement of the second inlet connector with the first receptacle of the infusion pump.

12. The infusion set of claim 8 , wherein the first inlet connector and the second inlet connector are shaped differently and wherein the first inlet connector comprises features that are configured to prevent engagement with the second medicament reservoir.

13. The infusion set of claim 12 , wherein the second inlet connector comprises features that are configured to prevent engagement with the first medicament reservoir.

14. The infusion set of claim 8 , wherein the first inlet connector comprises a first piercing element configured to insert into the first medicament reservoir to allow the first medicament to enter the first fluid path.

15. The infusion set of claim 14 , wherein the second inlet connector comprises a second piercing element configured to insert into the second medicament reservoir to allow the second medicament to enter the second fluid path.

16. An infusion set for delivering multiple medicaments to a patient, the infusion set comprising:

a base set comprising:

a first base unit having a first port and a first adhesive portion, the first base unit comprising a first cannula configured to deliver a first medicament to the patient, the first adhesive portion being configured to adhere the first base unit to the patient;

a second base unit having a second port and a second adhesive portion, the second base unit comprising a second cannula configured to deliver a second medicament to the patient, the second adhesive portion being configured to adhere the second base unit to the patient;

a connector set comprising:

a first distribution connector;

a first inlet connector;

a first fluid conduit connecting the first inlet connector to the first distribution connector and providing a first fluid path from the first inlet connector to the first distribution connector;

a second distribution connector;

a second inlet connector; and

a second fluid conduit connecting the second inlet connector to the second distribution connector and providing a second fluid path from the second inlet connector to the second distribution connector;

wherein the first distribution connector is configured to reversibly couple to the first base unit via the first port and the second distribution connector configured to reversibly couple to the second base unit via the second port;

wherein the first base unit comprises a first guide member that prevents engagement of the second distribution connector to the first base unit;

wherein the second base unit comprises a second guide member that prevents engagement of the first distribution connector to the second base unit;

wherein the first base unit and the second base unit are able to move independently with respect to each other and are configured to fit contours of a body of the patient during movements made by the patient;

wherein the first inlet connector is configured to engage a first medicament cartridge that is configured to house the first medicament, the first inlet connector being configured to allow fluidic communication between the first medicament cartridge and the first cannula;

wherein the second inlet connector is configured to engage a second medicament cartridge that is configured to house the second medicament, the second inlet connector being configured to allow fluidic communication between the second medicament cartridge and the second cannula;

wherein the first distribution connector comprises a single retention clip that locks the first distribution connector in place when in a coupled position with the first base unit;

wherein the single retention clip is configured to be depressed to allow one-handed de-coupling of the first distribution connector from the first base unit; and

wherein the first distribution connector and second distribution connector are each asymmetric.

17. The infusion set of claim 16 , wherein the first cannula and the second cannula are each flexible.

18. The infusion set of claim 16 , wherein the first inlet connector comprises engagement elements configured to engage a first receptacle of an infusion pump and to prevent engagement with a second receptacle of the infusion pump;

wherein the second inlet connector comprises engagement elements configured to engage the second receptacle of the infusion pump and to prevent engagement with the first receptacle of the infusion pump;

wherein the first inlet connector comprises features that are configured to prevent engagement with the second medicament cartridge; and

wherein the second inlet connector comprises features that are configured to prevent engagement with the first medicament cartridge.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 2, 2019
From: DAMIANO, EDWARD R.; SELAGAMSETTY, RAJENDRANATH; EL-KHATIB, FIRAS H.
To: TRUSTEES OF BOSTON UNIVERSITY
Reel/Frame 050602/0688 →
CONFIRMATORY LICENSE Recorded May 25, 2018
From: BOSTON UNIVERSITY CHARLES RIVER CAMPUS
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 046245/0930 →
Continuity (5)
Continuation PCTUS2016041395 · Jul 7, 2016
Provisional Application 62353210 · Jun 22, 2016
Provisional Application 62254950 · Nov 13, 2015
Provisional Application 62190212 · Jul 8, 2015
Related Publication 20180117296A1 · May 3, 2018
Cited By (6)
US 1,127,209 US 1,140,023 US 12,201,803 US 12,257,022 US 12,440,128 US 12,495,968