IP Library Granted Patent US 11,273,072
Granted Patent B2
US 11,273,072 · App. 15/865,533 · Granted Mar 15, 2022

Suprachoroidal injection device

Inventors: Daniel W. Price (Loveland, OH); Brendan J. Oberkircher (Cincinnati, OH); Daniel J. Prenger (Loveland, OH); Geoffrey King (Cincinnati, OH); Isaac J. Khan (Bridgewater, NJ); Michael F. Keane (Downington, PA)
Assignee: Gyroscope Therapeutics Limited
A61F9/00736A61F9/0008A61F9/0017A61F9/00781A61M5/46A61M2210/0612
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Quick Facts
Patent No.
US 11,273,072
App. No.
15/865,533
Granted
Mar 15, 2022
Kind
B2
Abstract

An apparatus includes a body, a cannula, a conduit, and a magnetic element. The cannula extends distally from the body. The cannula is flexible and has a distal end. The cannula defines a lumen distally terminating at the distal end. The cannula is sized and configured to pass between a sclera layer and a choroid layer in a human eye. The conduit is in fluid communication with the lumen. The magnetic element is positioned in the body.

Claims (18)

1. A method of delivering fluid to an eye of a patient, the method comprising:

(a) securing an instrument body relative to the patient;

(b) inserting a flexible cannula between an interior of a sclera layer and an exterior of a choroid layer of the eye of the patient, wherein the flexible cannula has an atraumatic distal end defining a distal opening, the flexible cannula extending distally from the instrument body, the act of inserting the flexible cannula being performed while the instrument body is secured relative to the patient;

(c) advancing the flexible cannula along a space between the sclera layer and the choroid layer to position the atraumatic distal end in a posterior region of the eye of the patient, the flexible cannula conforming to a curvature of the interior of the sclera layer during the act of advancing, the flexible cannula further separating a portion of the choroid layer from an adjacent portion of the sclera layer during the act of advancing, the act of advancing the flexible cannula being performed while the instrument body is secured relative to the patient; and

(d) dispensing a fluid into a space between the sclera layer and the choroid layer of the eye of the patient via the distal opening of the flexible cannula, the act of dispensing the fluid being performed while the instrument body is secured relative to the patient.

2. The method of claim 1 , further comprising forming an incision in the sclera layer, wherein the act of inserting comprises inserting the flexible cannula through the incision.

3. The method of claim 1 , further comprising securing a guide to the eye of the patient, wherein the act of inserting comprises passing the flexible cannula through a portion of the guide.

4. The method of claim 3 , wherein the guide comprises a suture loop assembly.

5. The method of claim 1 , wherein the act of securing the instrument body relative to the patient comprises securing the instrument body to the patient.

6. The method of claim 5 , wherein the body includes a magnetic element, the method further comprising securing a magnetic pad to the patient, wherein the act of securing the instrument body comprises engaging the magnetic element with the magnetic pad.

7. The method of claim 1 , wherein the act of dispensing the fluid comprises actuating a syringe, wherein the syringe is in fluid communication with the distal opening of the cannula.

8. The method of claim 1 , wherein the act of dispensing comprises dispensing the fluid into the space between the sclera layer and the choroid layer in the posterior region of the eye of the patient.

9. A method of delivering fluid to an eye of a patient, the method comprising:

(a) securing a body of an instrument to a patient, wherein the instrument includes a flexible cannula extending distally from the body, wherein the flexible cannula has an atraumatic open distal end;

(b) forming an incision in a sclera layer of an eye of the patient, the incision being formed in an anterior region of the eye of the patient;

(c) inserting the flexible cannula through the incision, thereby positioning the atraumatic open distal end of the cannula in a space between an interior of the sclera layer and an exterior of a choroid layer at a posterior region of the eye of the patient, wherein the flexible cannula conforms to a curvature defined by the sclera layer during the act of inserting, the act of inserting the flexible cannula being performed while the body is secured to the patient; and

(d) delivering a fluid via the open distal end of the cannula into the space between the sclera layer and the choroid layer at the posterior region of the eye of the patient, the act of delivering the fluid being performed while the body is secured to the patient.

10. The method of claim 9 , further comprising securing a magnetic pad relative to the patient, wherein the body of the instrument includes a magnetic element, wherein the act of securing the body of the instrument relative to a patient comprises achieving a magnetic coupling between the magnetic element and the magnetic pad.

Assignments (11)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 2, 2024
From: GYROSCOPE THERAPEUTICS LIMITED
To: F. HOFFMANN-LA ROCHE AG
Reel/Frame 069091/0527 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 2, 2024
From: F. HOFFMANN-LA ROCHE AG
To: GENENTECH, INC.
Reel/Frame 069097/0746 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 27, 2021
From: ETHICON LLC
To: CILAG GMBH INTERNATIONAL
Reel/Frame 056601/0339 →
CORRECTIVE ASSIGNMENT TO CORRECT THE THE ASSIGNOR SHOULD READ "ORBIT BIOMEDICAL LIMITED" PREVIOUSLY RECORDED ON REEL 053762 FRAME 0437. ASSIGNOR(S) HEREBY CONFIRMS THE THE ORIGINAL READ "ORBIT BIOMEDICAL LIMTED". Recorded Sep 23, 2020
From: ORBIT BIOMEDICAL LIMITED
To: GYROSCOPE THERAPEUTICS LIMITED
Reel/Frame 053856/0539 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 14, 2020
From: ORBIT BIOMEDICAL LIMTED
To: GYROSCOPE THERAPEUTICS LIMITED
Reel/Frame 053762/0437 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 21, 2018
From: ETHICON LLC
To: JANSSEN BIOTECH, INC.
Reel/Frame 045855/0961 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 21, 2018
From: PRENGER, DANIEL J.; KING, GEOFFREY
To: SAEC/KINETIC VISION, INC.
Reel/Frame 045856/0178 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 21, 2018
From: SAEC/KINETIC VISION, INC.
To: JANSSEN BIOTECH, INC.
Reel/Frame 045856/0520 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 21, 2018
From: KHAN, ISAAC J.; KEANE, MICHAEL F.
To: JANSSEN BIOTECH, INC.
Reel/Frame 045857/0020 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 21, 2018
From: JANSSEN BIOTECH, INC.
To: ORBIT BIOMEDICAL LIMITED
Reel/Frame 045857/0619 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 21, 2018
From: PRICE, DANIEL W.; OBERKIRCHER, BRENDAN J.
To: ETHICON LLC
Reel/Frame 045855/0822 →
Continuity (2)
Provisional Application 62445866 · Jan 13, 2017
Related Publication 20180200108A1 · Jul 19, 2018