IP Library Granted Patent US 10,603,344
Granted Patent B2
US 10,603,344 · App. 15/866,726 · Granted Mar 31, 2020

Plant extract from low-THC cannabis for the treatment of disease

Inventors: Heinz Letzel (Grainau, DE); Regina Klaeger (Landsberg, DE); Rudolph Klaeger (Landsberg, DE)
Assignee: Canopy Growth Corporation
A61K36/185A61K8/97A61Q19/00A61Q19/008
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Quick Facts
Patent No.
US 10,603,344
App. No.
15/866,726
Granted
Mar 31, 2020
Kind
B2
Abstract

The present invention relates to a plant extract from a low-tetrahydrocannabinol (THC) variety of Cannabis sativa subsp. sativa for the treatment of disease. The invention further relates to the production of the extract and pharmaceutical compositions comprising said extract and the uses thereof.

Claims (16)

1. A method of treating a human patient suffering from acne, psoriasis, or atopic dermatitis comprising administering to said human patient suffering from acne, psoriasis, or atopic dermatitis a therapeutically effective amount of Cannabis sativa subspecies sativa Futura 75 to effectively treat the acne, psoriasis, or atopic dermatitis in the human patient suffering from the acne, psoriasis, or atopic dermatitis.

2. The method of claim 1 , wherein the Cannabis sativa subspecies sativa Futura 75 is from at least one of mechanically pulverized flowers, flower-proximal leaves, stalks, roots, and seeds of a low-tetrahydrocannabinol variety, wherein the tetrahydrocannabinol content is less than 0.5 wt. %.

3. The method of claim 2 , wherein the Cannabis sativa subspecies sativa Futura 75 is extracted using a solvent selected from the group consisting of water, a saline solution, an alcohol, acetone, an ester, and an ether.

4. The method of claim 3 , wherein the solvent is 0.9% saline solution, 90% ethanol, or 70% isopropanol.

5. The method of claim 1 , wherein the tetrahydrocannabinol content is less than 0.2 weight %.

6. The method of claim 1 , wherein the Cannabis sativa subspecies sativa Futura 75 is in the form of a salve, a cream, a gel, a lotion, a paste, or an emulsion.

7. A method of treating a human patient suffering from acne, psoriasis, or atopic dermatitis comprising:

obtaining an isopropanol extract of low-tetrahydrocannabinol variety of Cannabis sativa subspecies sativa using a solvent comprising isopropanol; and

administering to said human patient suffering from acne, psoriasis, or atopic dermatitis a therapeutically effective amount of the isopropanol extract or a pharmaceutical composition containing said isopropanol extract to effectively treat the acne, psoriasis, or atopic dermatitis in the human patient suffering from the acne, psoriasis, or atopic dermatitis.

8. The method of claim 7 , wherein the Cannabis sativa subspecies sativa is at least one of mechanically pulverized flowers, flower-proximal leaves, stalks, roots, and seeds of the Cannabis sativa subspecies sativa .

9. The method of claim 7 , wherein the tetrahydrocannabinol content of the Cannabis sativa subspecies sativa is less than 0 . 5 wt. %.

10. The method of claim 9 , wherein the tetrahydrocannabinol content of the Cannabis sativa subspecies sativa is less than 0.2 wt. %.

11. The method of claim 7 , wherein the isopropanol extract is in the form of a salve, cream, a gel, a lotion, a paste, or an emulsion.

12. The method of claim 7 , wherein the solvent further comprises water, a saline solution, acetone, an ester, or an ether.

13. The method of claim 7 , wherein the solvent is 70% isopropanol.

14. The method of claim 7 , wherein the Cannabis sativa subspecies sativa is Futura 75.

Assignments (5)
SECURITY INTEREST Recorded Jan 20, 2026
From: CANOPY GROWTH CORPORATION; TWEED INC.
To: JGB COLLATERAL LLC
Reel/Frame 073521/0250 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 10, 2020
From: CANOPY GROWTH CORPORATION
To: BIONORICA SE
Reel/Frame 054603/0863 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 18, 2019
From: BIONORICA SE
To: CANOPY GROWTH CORPORATION
Reel/Frame 049791/0507 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 24, 2019
From: KLAEGER, REGINA; KLAEGER, RUDOLPH
To: BIONORICA SE
Reel/Frame 049281/0477 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 2, 2019
From: LETZEL, HEINZ, DR.
To: KLAEGER, REGINA, DR.; KLAEGER, RUDOLPH
Reel/Frame 049079/0976 →