Granted Patent B2

US 10,342,892 · App. 15/874,418 · Granted Jul 9, 2019

Abstract

Claims (19)

1. A putty composition consisting of:

(a) about 55% to about 65%, by weight of the composition, poloxamer 407;

(b) about 5 to about 15%, by weight of the composition, dextran having a molecular weight of about 500,000 Daltons;

(c) about 20% to about 30%, by weight of the composition, phosphate buffered saline, and

(d) about 5% to about 10%, by weight of the composition, calcium stearate.

2. A putty composition consisting of:

(a) about 55% to about 65%, by weight of the composition, poloxamer 407;

(b) about 5 to about 15%, by weight of the composition, dextran having a molecular weight of about 500,000 Daltons;

(c) about 20% to about 30%, by weight of the composition, phosphate buffered saline,

(d) about 5% to about 10%, by weight of the composition, calcium stearate, and

(e) calcium phosphate material selected from the group consisting of hydroxyapatite, α-tricalcium phosphate, β-tricalcium phosphate, demineralized bone matrix, and combinations thereof.

3. The composition of claim 1 or 2 , wherein the composition is sterile.

4. A package comprising the composition of claim 1 or 2 wherein the composition is amorphous or in a generally rounded form or in a generally parallelepiped form, wherein said composition is sealed in an aseptic barrier package, and is sterile or sterilizable.

5. A putty composition consisting of:

(a) about 10% to about 30%, by weight of the composition, poloxamer 407;

(b) about 30% to about 50%, by weight of the composition, dextran having a molecular weight of about 500,000 Daltons;

(c) about 30% to about 50%, by weight of the composition, phosphate buffered saline, and

(d) about 0% to about 5%, by weight of the composition, calcium stearate.

6. The putty composition of claim 5 wherein the amount of poloxamer 407 is about 20%, the amount of dextran is about 40%, the amount of phosphate buffered saline is about 40% and the amount of calcium stearate is 0%.

Assignments (11)