IP Library Granted Patent US 12,042,793
Granted Patent B2
US 12,042,793 · App. 15/874,762 · Granted Jul 23, 2024

Dry chemistry container

Inventors: Holger Engel (Hilden, DE); Jordi Carrera Fabra (Puigcerda, ES); Anna Comengés Casas (Barcelona, ES); Ricard Martín Blanco (Badalona, ES); Martin Alan Lee (Wiltshire, GB); Diane Rachel Lee (Wiltshire, GB)
Assignee: QIAGEN GmbH
B01L3/502715B01J19/0093B01L3/523B01J2219/00891B01L2200/025B01L2200/026B01L2200/10B01L2200/16B01L2200/18B01L2300/041B01L2300/042B01L2300/046B01L2300/048B01L2300/0609B01L2300/0832B01L2300/0861B01L2300/16
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Quick Facts
Patent No.
US 12,042,793
App. No.
15/874,762
Granted
Jul 23, 2024
Kind
B2
Abstract

A microfluidic system is presented that includes a cartridge, a container, and a lid for the container. The cartridge includes a plurality of microfluidic channels coupled to one or more chambers. The container holds dry chemicals and includes a housing with a first opening and a second opening smaller than the first opening. The container is designed to be inserted into an opening of the cartridge, such that the container is independently secured within the opening. The insertion of the container allows for the container to be fluidically coupled with a microfluidic channel of the plurality of microfluidic channels via the second opening. The lid includes a column that extends from the lid into the container.

Claims (13)

1. A microfluidic system, comprising:

a cartridge having an opening and a plurality of microfluidic channels coupled to one or more chambers;

a container having a housing with a first opening and a second opening smaller than the first opening, wherein the container is sized and shaped to hold dry chemicals and to be inserted into the opening of the cartridge, the opening of the cartridge being sized to receive at least a portion of the container within the opening of the cartridge such that no fluid leakage occurs between the container and the cartridge and the container is independently secured within the opening of the cartridge and is fluidically coupled with a microfluidic channel of the plurality of microfluidic channels via the second opening of the container; and

a lid configured to seal the first opening of the container and comprising:

a seal structure configured to press against an inner wall of the housing; and

a column that extends from the lid into a central chamber of the housing.

2. The microfluidic system of claim 1 , wherein the housing has a first cylindrical portion and a second cylindrical portion smaller than the first cylindrical portion.

3. The microfluidic system of claim 2 , wherein a diameter of the first cylindrical portion is substantially equal to a diameter of the first opening and a diameter of the second cylindrical portion is substantially equal to a diameter of the second opening.

4. The microfluidic system of claim 2 , wherein the container further comprises one or more structures that protrude outward from the first cylindrical portion and are configured to hold the container within the opening of the cartridge.

5. The microfluidic system of claim 4 , wherein the cartridge includes respective structures or indentations that mate with the one or more structures.

6. The microfluidic system of claim 1 , wherein the column includes a tip at a distal end of the column, the tip having a round shape or a conical shape.

7. The microfluidic system of claim 1 , wherein a distal end of the column is sized and shaped to contact the dry chemicals to prevent the dry chemicals within the container from becoming dislodged.

8. The microfluidic system of claim 7 , wherein the dry chemicals include freeze-dried reagents.

Assignments (3)
CHANGE OF NAME Recorded Nov 30, 2023
From: STAT-DIAGNOSTICA & INNOVATION, S.L.
To: STAT-DX LIFE S.L.
Reel/Frame 066335/0871 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 30, 2023
From: STAT-DX LIFE S.L.
To: QIAGEN GMBH
Reel/Frame 065729/0209 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 28, 2022
From: ENGEL, HOLGER; CARRERA FABRA, JORDI; COMENGÉS CASAS, ANNA; MARTÍN BLANCO, RICARD; LEE, MARTIN ALAN; LEE, DIANE RACHEL
To: STAT-DIAGNOSTICA & INNOVATION, S.L.
Reel/Frame 060663/0426 →
Continuity (1)
Related Publication 20190217292A1 · Jul 18, 2019