IP Library Granted Patent US 10,888,429
Granted Patent B2
US 10,888,429 · App. 15/877,002 · Granted Jan 12, 2021

Three-dimensional lattice structures for implants

Inventors: Christopher L. Jones (Malden, MA); Ian Helmar (Beverly, MA); Lucas Diehl (Beverly, MA); Jason Tinley (Fort Worth, TX); Kevin D. Chappuis (Malden, MA); John F. Sullivan (Pelham, NH)
Assignee: HD LIFESCIENCES LLC
A61F2/3094A61C8/0013A61C13/0019A61F2/28A61F2/2846A61F2/30771A61F2/30907A61F2/30942A61F2/44A61F2/4455A61L27/505A61L27/56B33Y80/00A61F2/30767A61F2002/0081A61F2002/2835A61F2002/30006A61F2002/30014A61F2002/3014A61F2002/30069A61F2002/3092A61F2002/3093A61F2002/30113A61F2002/30141A61F2002/30143A61F2002/30146A61F2002/30148A61F2002/30151A61F2002/30154A61F2002/30156A61F2002/30263A61F2002/30273A61F2002/30677A61F2002/30766A61F2002/30914A61F2002/30919A61F2002/30943A61F2210/0057A61F2240/001A61F2310/00023A61L2430/02B29C64/165
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Quick Facts
Patent No.
US 10,888,429
App. No.
15/877,002
Granted
Jan 12, 2021
Kind
B2
Abstract

The three-dimensional lattice structures disclosed herein have applications including use in medical implants. Some examples of the lattice structure are structural in that they can be used to provide structural support or mechanical spacing. In some examples, the lattice can be configured as a scaffold to support bone or tissue growth. Some examples can use a repeating modified rhombic dodecahedron or radial dodeca-rhombus unit cell.

Claims (31)

1. A structure for use in medical implants, the structure comprising:

a three-dimensional lattice structure configured to extend between two adjacent bony structures and provide sole mechanical spacing between the two adjacent bony structures, the three-dimensional lattice comprising:

a plurality of repeating unit cells; and

a plurality of fluidly interconnected openings disposed within a volume of the three-dimensional lattice, the plurality of fluidly interconnected openings comprising a first group of openings comprising a first width and a second group of openings comprising a second width, the second width being greater than the first width and number of openings in the second group of openings being a ratio of about 1:1 to 1:25 of number of openings in the first group of openings.

2. The structure of claim 1 , wherein the plurality of unit cells comprise a rhombic dodecahedron structure defined by struts within an amorphous volume defined by the three-dimensional lattice structure.

3. The structure of claim 1 , wherein the plurality of unit cells comprise a radial dodeca-rhombus structure defined by struts within an amorphous volume defined by the three-dimensional lattice structure.

4. The structure of claim 1 , wherein the three-dimensional lattice structure comprises a volumetric density between and including 5 percent to 40 percent.

5. The structure of claim 1 , wherein the at least two areas of tissue comprise bony structures.

6. The structure of claim 1 , wherein the three-dimensional lattice structure comprises a volumetric density between and including 30 percent to 38 percent and the openings in the second group of openings are included at a ratio of about 1:8 to 1:12 per opening included in the first group of openings in the three-dimensional lattice structure.

7. The structure of claim 1 , wherein the three-dimensional lattice structure comprises an elastic modulus between and including 0.375 GPa to 4 GPa.

8. The structure of claim 1 , wherein the three-dimensional lattice structure comprises a shear yield load and a compressive yield between and including 300 to 15000N in static and dynamic loading up to 5,000,000 cycles at 5 Hz.

9. The structure of claim 1 , wherein the first width is between and including 200 μm to 900 μm, and the second width B is 1 to 15 times as large as the first width.

10. The structure of claim 1 , wherein the three-dimensional lattice structure comprises a torsional yield load up to 15 Nm.

11. The structure of claim 1 , wherein the three-dimensional lattice structure comprises a volumetric density of 5 percent to 40 percent, an elastic modulus between and including 0.375 MPa to 4 GPa, a compressive shear strength and an axial load between and including 300 to 15000N in static and dynamic loading up to 5,000,000 cycles at 5 Hz.

12. The structure of claim 1 , wherein the three-dimensional lattice structure comprises a volumetric density of 32 percent to 38 percent, an elastic modulus between and including 2.5 GPa to 4 GPa and a shear strength and an axial load between and including 300 to 15000N in static and dynamic loading up to 5,000,000 cycles at 5 Hz.

13. The lattice structure of claim 1 , wherein the three-dimensional lattice structure comprises a volumetric density of 32 percent to 38 percent, an elastic modulus between and including 2.5 GPa to 4 GPa, a compressive shear strength and an axial load between and including 300 to 15000N in static and dynamic loading up to 5,000,000 cycles at 5 Hz.

14. The lattice structure of claim 1 , wherein the plurality of unit cells comprise a radial dodeca-rhombus structure defined by struts within an amorphous volume of the three-dimensional lattice structure.

15. A structure for use in medical implants, the structure comprising:

a three-dimensional lattice structure configured to provide sole mechanical spacing between at least two areas of a location where the structure is implanted, the three-dimensional lattice comprising:

a plurality of struts; and

a plurality of fluidly interconnected openings defined by the plurality of struts, the plurality of openings comprising a first group of openings configured to promote osteoblast in-growth and a second group of openings configured to promote osteon in-growth;

wherein a width of the second group of openings is larger than a width of the first group of openings.

16. The structure of claim 15 , wherein the three-dimensional lattice structure comprises a plurality of repeating unit cells bound by a predetermined amorphic volume and containing a rhombic dodecahedron structure defined by the plurality of struts.

17. The structure of claim 15 , wherein the three-dimensional lattice structure comprises a plurality of repeating unit cells bound by a predetermined amorphic volume and containing a radial dodeca-rhombus structure defined by the plurality of struts.

18. The structure of claim 15 , wherein the three-dimensional lattice structure comprises a volumetric density between and including 5 percent to 40 percent.

19. The structure of claim 15 , wherein the at least two areas comprise two bony structures that are part of one continuous segment of bone.

20. The structure of claim 15 , wherein the three-dimensional lattice structure comprises a volumetric density of between and including 30 percent to 38 percent, the first group of openings comprise a substantially homogeneous width of about 200 μm to 900 μm, and the second group of openings comprise a substantially homogenous width of about 1 to 15 times of the width of the first group of openings.

21. The structure of claim 15 , wherein the three-dimensional lattice structure comprises a shear yield load between and including 300 to 15000N in static and dynamic loading up to 5,000,000 cycles at 5 Hz.

22. The structure of claim 15 , wherein the three-dimensional lattice structure comprises a compressive yield load between and including 300 to 15000N in static and dynamic loading up to 5,000,000 cycles at 5 Hz.

23. The structure of claim 15 , wherein the three-dimensional lattice structure comprises a torsional yield load up to 15 Nm.

24. The structure of claim 15 , wherein the three-dimensional lattice structure comprises a volumetric density of 32 percent to 38 percent, an elastic modulus between and including 2.5 GPa to 4 GPa and a shear strength and an axial load between and including 300 to 15000N in static and dynamic loading up to 5,000,000 cycles at 5 Hz and wherein a number of openings in the second group of openings are at a ratio of about 1:8 to 1:12 relative to number of openings in the second group of openings.

Assignments (4)
SECURITY INTEREST Recorded Sep 10, 2025
From: NANOHIVE MEDICAL LLC
To: EV LENDING LLC
Reel/Frame 072212/0859 →
SECURITY INTEREST Recorded Nov 28, 2023
From: NANOHIVE MEDICAL LLC
To: KENSTON CAPITAL EMERGING TECHNOLOGY FUND I LP
Reel/Frame 065683/0739 →
CHANGE OF NAME Recorded Feb 3, 2023
From: HD LIFESCIENCES LLC
To: NANOHIVE MEDICAL LLC
Reel/Frame 062660/0039 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 22, 2018
From: TINLEY, JASON, DR.; CHAPPUIS, KEVIN; JONES, CHRISTOPHER L., DR.; DIEHL, LUCAS; HELMAR, IAN; SULLIVAN, JOHN F.
To: HD LIFESCIENCES LLC
Reel/Frame 044693/0018 →
Continuity (4)
Provisional Application 62480383 · Apr 1, 2017
Provisional Application 62480393 · Apr 1, 2017
Provisional Application 62619260 · Jan 19, 2018
Related Publication 20180280145A1 · Oct 4, 2018
Cited By (1)
US 12,514,710