IP Library › Granted Patent US 10,383,977
Granted Patent B2
US 10,383,977 · App. 15/877,586 · Granted Aug 20, 2019

Cardiovascular prostheses

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Quick Facts
Patent No.
US 10,383,977
App. No.
15/877,586
Granted
Aug 20, 2019
Kind
B2
Abstract

Polymeric grafts for treating damaged biological tissue that are formed from poly(glycerol sebacate) (PGS). The PGS grafts preferably comprise a bioactive agent comprising anti-inflammatory corticosteroids, anti-oxidants, anti-thrombotic agents and anti-platelet agents. The PGS grafts can also comprise a HMG-CoA reductase inhibitor.

Claims (2)

1. A prosthesis for treating damaged cardiovascular tissue, comprising:

a sheet member consisting of an ECM-mimicking composition and a pharmacological agent, said ECM-mimicking composition consisting of poly(glycerol sebacate), said pharmacological agent consisting of a HMG-CoA reductase inhibitor consisting of cerivastatin.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 12, 2025
From: CORMATRIX CARDIOVASCULAR, INC.
To: CORVIVO CARDIOVASCULAR, INC.
Reel/Frame 070482/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 8, 2018
From: MATHENY, ROBERT G
To: CORMATRIX CARDIOVASCULAR, INC
Reel/Frame 044868/0888 →
Cited By (1)
US 12,514,958