IP Library Granted Patent US 10,436,687
Granted Patent B2
US 10,436,687 · App. 15/887,855 · Granted Oct 8, 2019

Transfer vessel and methods for reducing sample loss

Inventors: Clarissa Lui (Menlo Park, CA); Priyanshu Gupta (Hornsby, AU)
Assignee: Theranos IP Company, LLC
G01N1/4077B01L3/5021B01L3/5023G01N33/491B01L2200/025B01L2200/06B01L2200/0642B01L2200/10B01L2300/047B01L2300/069B01L2300/0609B01L2300/0858B01L2300/0867B01L2400/0409G01N2001/4083
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,436,687
App. No.
15/887,855
Granted
Oct 8, 2019
Kind
B2
Abstract

Devices, systems and methods for holding and transferring small volume fluid samples are disclosed. Holding vessels, including holding vessels having two or more internal compartments for holding small volume fluid samples, are disclosed. Transfer vessels for receiving small volume fluid samples from such holding vessels are disclosed. Transfer vessels for combining small volume fluid samples from such holding vessels are disclosed. Methods for providing small volume fluid samples for analysis with small loss of sample are disclosed. Methods for providing small volume fluid samples for analysis using automated sample analysis devices and systems, with small loss of sample, are disclosed.

Claims (21)

1. A method of providing a small volume fluid sample for analysis, comprising:

placing small volume fluid samples in separate compartments of a holding vessel having at least two compartments, each compartment containing gel and having a compartment mouth;

centrifuging the holding vessel;

placing the holding vessel with each compartment mouth positioned in or near the mouth of a transfer vessel; and

applying gentle centrifugation to the holding vessel and transfer vessel, wherein the holding vessel mouths and the transfer vessel mouth remain in position during said gentle centrifugation effective that a fraction of the sample flows from both the compartments of the holding vessel into the transfer vessel.

2. The method of claim 1 , wherein said small volume fluid sample is a small volume blood sample.

3. The method of claim 1 , wherein said small volume fluid sample is a fingerstick blood sample.

4. The method of claim 1 , further comprising analyzing the fluid sample with an automated sample analysis device.

5. The method of claim 1 , further comprising analyzing the fluid sample with an automated sample analysis system.

6. A method of providing a small volume fluid sample for analysis, comprising:

placing small volume fluid samples in separate compartments of a holding vessel having at least two compartments, each compartment containing gel and having a compartment mouth;

centrifuging the holding vessel;

placing the holding vessel with each compartment mouth positioned in or near the mouth of a transfer vessel; and

applying gentle centrifugation to the holding vessel and transfer vessel, wherein the holding vessel mouths and the transfer vessel mouth remain in position during said gentle centrifugation effective that a fraction of the sample flows from both the compartments of the holding vessel into the transfer vessel;

wherein said gel comprises plasma separation gel.

7. A method of providing a small volume fluid sample for analysis, comprising:

placing small volume fluid samples in separate compartments of a holding vessel having at least two compartments, each compartment containing gel and having a compartment mouth;

centrifuging the holding vessel;

placing the holding vessel with each compartment mouth positioned in or near the mouth of a transfer vessel; and

applying gentle centrifugation to the holding vessel and transfer vessel, wherein the holding vessel mouths and the transfer vessel mouth remain in position during said gentle centrifugation effective that a fraction of the sample flows from both the compartments of the holding vessel into the transfer vessel;

wherein said fraction of the sample that flows from both the compartments of the holding vessel into the transfer vessel is a plasma sample.

Assignments (3)
CHANGE OF NAME Recorded Apr 3, 2020
From: THERANOS IP COMPANY, LLC
To: LABRADOR DIAGNOSTICS LLC
Reel/Frame 052313/0011 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 16, 2018
From: LUI, CLARISSA; GUPTA, PRIYANSHU
To: THERANOS, INC.
Reel/Frame 045258/0734 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 16, 2018
From: THERANOS, INC.
To: THERANOS IP COMPANY, LLC
Reel/Frame 045615/0891 →
Continuity (3)
Continuation PCTUS2016045199 · Aug 2, 2016
Provisional Application 62200642 · Aug 4, 2015
Related Publication 20180224361A1 · Aug 9, 2018