COMPOSITIONS OF HERBAL FORMULATIONS AND USES THEREOF

1 . A composition comprising a mixture of plant extracts, wherein the mixture comprises:

a) at least one Group I plant extract and at least one Group II plant extract, wherein the at least one Group I plant extract and the at least one Group II plant extract are different;

b) at least one Group I plant extract and at least one Group III plant extract, wherein the at least one Group I plant extract and the at least one Group III plant extract are different;

c) at least one Group I plant extract and at least one Group IV plant extracts, wherein the at least one Group I plant extract and the at least one Group IV plant extract are different;

d) at least one Group II plant extract and at least one Group III plant extracts, wherein the at least one Group II plant extract and the at least one Group III plant extract are different;

e) at least one Group II plant extract and at least one Group IV plant extract, wherein the at least one Group II plant extract and the at least one Group IV plant extract are different;

f) at least one Group III plant extract and at least one Group IV plant extract, wherein the at least one Group III plant extract and the at least one Group IV plant extract are different;

g) at least one Group I plant extract, at least one Group II plant extract, and at least one Group III plant extract, wherein the at least one Group I plant extract, the at least one Group II plant extract, and the at least one Group III plant extract are different;

h) at least one Group I plant extract, at least one Group II plant extract, and at least one Group IV plant extract, wherein the at least one Group I plant extract, the at least one Group II plant extract, and the at least one Group IV plant extract are different;

i) at least one Group I plant extract, at least one Group III plant extract, and at least one Group IV plant extract, wherein the at least one Group I plant extract, the at least one Group III plant extract, and the at least one Group IV plant extract are different; or

j) at least one Group II plant extract, at least one Group III plant extract, and at least one Group IV plant extracts, wherein the at least one Group II plant extract, the at least one Group III plant extract, and the at least one Group IV plant extract are different;

wherein:

Group I comprises a plant extract obtained from a plant selected from the group consisting of: Althaea officinalis; Ervum lens; Populas alba; Populus tremuloides; Conium maculatium; Sambucus nigra; Hamamelis virginiana ; and Phytolacca decendra;

Group II comprises a plant extract obtained from a plant selected from the group consisting of: Conium maculatium; Phytolacca decendra; Pimpinella saxifraga; Rhus toxicodendron ; and Vincetoxicum officinale;

Group III comprises a plant extract obtained from a plant selected from the group consisting of: Avena sativa; Aesuculus hippocastanum; Capsella Bursa Pastoris; Hamamelis virginiana; Hydrastis canadensis; Achillea millefolium ; and Sanguinaria Canadensis ; and

Group IV comprises a plant extract obtained from a plant selected from the group consisting of: Berberis vulgaris; Matricaria chamomilla; Cochlearia officinalis; Hydrastis canadensis; Nasturtium officinale; Scrophularia nodosa; Smilax medica; Tussilago farfara ; and Veronica officinalis.

2 . The composition of claim 1 , wherein the composition comprises at least two herbal extracts each of which is present in the following amount (w/w): Achillea millefolium from about 0.01% to about 20%; Aesuculus hippocastanum from about 0.01% to about 20%; Althaea officinalis from about 0.01% to about 20%; Avena sativa from about 0.01% to about 25%; Berberis vulgaris from about 0.01% to about 20%; Capsella Bursa Pastoris from about 0.01% to about 20%; Cochlearia officinalis from about 0.01% to about 20%; Conium maculatium from about 0.01% to about 35%; Ervum lens from about 0.01% to about 20%; Hamamelis virginiana from about 0.01% to about 25%; Hydrastis canadensis from about 0.01% to about 20%; Matricaria chamomilla from about 0.01% to about 20%; Nasturtium officinale from about 0.01% to about 15%; Phytolacca decendra from about 0.01% to about 20%; Pimpinella saxifraga from about 0.01% to about 20%; Populas alba from about 0.01% to about 20%; Populus tremuloides from about 0.01% to about 20%; Rhus toxicodendron from about 0.01% to about 25%; Sambucus nigra from about 0.01% to about 20 ; Sanguinaria Canadensis from about 0.01% to about 20%; Scrophularia nodosa from about 0.01% to about 20%; Smilax medico from about 0.01% to about 20%; Tussilago farfara from about 0.01% to about 15%; Veronica officinalis from about 0.01% to about 15%; and Vincetoxicum officinale from about 0.01% to about 15%.

3 . The composition of claim 1 , comprising an extract selected from the group consisting of:

i) Althaea officinalis from about 1% to about 15%; or from about 1% to about 10%; or from about 1% to about 8%; or from about 1.5% to about 7%; or from about 1.5% to about 5%;

ii) Ervum lens from about 1% to about 17%; or from about 1% to about 15%; or from about 3% to about 12%; or from about 3% to about 10%;

iii) Populas alba from about 1% to about 17%; or from about 3% to about 15%; or from about 3% to about 12%; or from about 4% to about 10%;

iv) Populus tremuloides from about 1% to about 17%; or from about 3% to about 15%; or from about 3% to about 12%; or from about 4% to about 10%;

v) Conium maculatium from about 1% to about 30%; or from about 1% to about 25%; or from about 3.5% to about 23%;

vi) Sambucus nigra from about 1% to about 15%; or from about 1% to about 10%; or from about 1% to about 8%; or from about 1.5% to about 7%; or from about 1.5% to about 6%;

vii) Hamamelis virginiana from about 1% to about 25%; or from about 3% to about 20%; or from about 5% to about 17%; or from about 5% to about 15%; and

viii) Phytolacca decendra from about 1% to about 17%; or from about 3% to about 15%; or from about 3% to about 12%; or from about 3.5% to about 10%.

4 . The composition of claim 1 , comprising an extract selected from the group consisting of:

i) Conium maculatium from about 1% to about 30%; or from about 1% to about 25%; or from about 3.5% to about 23%;

ii) Phytolacca decendra from about 1% to about 17%; or from about 3% to about 15%; or from about 3% to about 12%; or from about 3.5% to about 10%;

iii) Pimpinella saxifraga from about 0% to about 12%; or from about 0% to about 10%; or from about 0.1% to about 8%; or from about 0.5% to about 5%;

iv) Rhus toxicodendron from about 1% to about 25%; or from about 3% to about 20%; or from about 5% to about 20%; or from about 7% to about 20%; and

v) Vincetoxicum officinale from about 0% to about 12%; or from about 0% to about 10%; or from about 0.1% to about 8%; or from about 0.1% to about 5%.

5 . The composition of claim 1 , comprising an extract selected from the group consisting of:

i) Avena sativa from about 1% to about 25%; or from about 3% to about 20%; or from about 5% to about 17%; or from about 5% to about 15%;

ii) Aesuculus hippocastanum from about 1% to about 15%; or from about 1% to about 10%; or from about 1% to about 8%; or from about 1.5% to about 7%; or from about 2% to about 6%;

iii) Capsella Bursa Pastoris from about 1% to about 17%; or from about 1% to about 15%; or from about 1.5% to about 12%; or from about 1.5% to about 10%;

iv) Hamamelis virginiana from about 1% to about 25%; or from about 3% to about 20%; or from about 5% to about 17%; or from about 5% to about 15%;

v) Hydrastis canadensis from about 1% to about 17%; or from about 3% to about 15%; or from about 3% to about 12%; or from about 3.5% to about 10%;

vi) Achillea millefolium from about 1% to about 15%; or from about 1% to about 10%; or from about 1% to about 8%; or from about 1.5% to about 7%; or from about 2% to about 6%; and

vii) Sanguinaria Canadensis from about 1% to about 17%; or from about 3% to about 15%; or from about 3% to about 12%; or from about 4% to about 10.

6 . The composition of claim 1 , comprising an extract selected from the group consisting of:

i) Berberis vulgaris from about 1% to about 17%; or from about 1% to about 15%; or from about 3% to about 12%; or from about 3% to about 10%;

ii) Matricaria chamomilla from about 1% to about 17%; or from about 1% to about 15%; or from about 1.5% to about 12%; or from about 1.5% to about 10%;

iii) Cochlearia officinalis from about 1% to about 17%; or from about 3% to about 15%; or from about 3% to about 12%; or from about 4% to about 10%;

iv) Hydrastis canadensis from about 1% to about 17%; or from about 3% to about 15%; or from about 3% to about 12%; or from about 3.5% to about 10%;

v) Nasturtium officinale from about 0% to about 12%; or from about 0% to about 10%; or from about 0.1% to about 8%; or from about 0.1% to about 5%;

vi) Scrophularia nodosa from about 1% to about 17%; or from about 3% to about 15%; or from about 3% to about 12%; or from about 4% to about 10%;

vii) Smilax medica from about 1% to about 15%; or from about 1% to about 10%; or from about 1% to about 8%; or from about 1.5% to about 7%; or from about 2% to about 6.5%;

viii) Tussilago farfara from about 0% to about 12%; or from about 0% to about 10%; or from about 0.1% to about 8%; or from about 0.1% to about 5%; and

ix) Veronica officinalis from about 0% to about 12%; or from about 0% to about 10%; or from about 0.1% to about 8%; or from about 0.1% to about 5%.

7 . The composition of claim 1 , further comprising a physiologically acceptable carrier, diluent, or excipient.

8 . The composition of claim 1 , wherein the composition is formulated for topical application.

9 . The composition of claim 1 , wherein the composition is an aqueous solution.

10 . A method of reducing symptoms associated with a skin condition in a subject, comprising identifying the subject in need thereof and administering to the subject an effective amount of the composition of claim 1 .

11 . The method of claim 10 , wherein the skin condition is associated with acne vulgaris, psoriasis, eczema, or atopic dermatitis.

12 . The method of claim 10 , wherein the skin condition is pruritis, erythema, or excoriations.