IP Library Granted Patent US 10,272,060
Granted Patent B2
US 10,272,060 · App. 15/889,961 · Granted Apr 30, 2019

Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof

Inventors: Kirk E. Apt (Ellicott City, MD); Paul Warren Behrens (Ellicott City, MD); Jon Milton Hansen (Chandler, AZ); Joseph W. Pfeifer, III (Westminster, MD); Tracey Lynn Stahl (Pasadena, MD); Ross Zirkle (Mt. Airy, MD)
Assignee: DSM IP Assets B.V.
A61K31/202A23K20/158A23K50/80A23L2/52A23L33/12A23L33/40A61K8/361A61Q19/00C12P7/6427A23V2002/00A61K2800/10
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Quick Facts
Patent No.
US 10,272,060
App. No.
15/889,961
Granted
Apr 30, 2019
Kind
B2
Abstract

The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.

Claims (7)

1. A vegetable oil comprising omega-3 polyunsaturated fatty acids which comprise docosahexaenoic acid and eicosapentaenoic acid in an amount of about >90%, by weight, of the total amount of omega-3 polyunsaturated fatty acids, wherein the amount of eicosapentaenoic acid, by weight, is from about 19% to about 55% of the total amount of docosahexaenoic acid and eicosapentaenoic acid, and the amount of docosahexaenoic acid, by weight, is from about 35% to about 71% of the total amount of docosahexaenoic acid and eicosapentaenoic acid.

2. The oil of claim 1 , wherein the amount of eicosapentaenoic acid, by weight, is from about 19% to about 43% of the total amount of docosahexaenoic acid and eicosapentaenoic acid, and the amount of docosahexaenoic acid, by weight, is from about 35% to about 47% of the total amount of docosahexaenoic acid and eicosapentaenoic acid.

3. The oil of claim 1 , wherein the amount of eicosapentaenoic acid, by weight, is from about 27% to about 54% of the total amount of docosahexaenoic acid and eicosapentaenoic acid, and the amount of docosahexaenoic acid, by weight, is from about 36% to about 63% of the total amount of docosahexaenoic acid and eicosapentaenoic acid.

4. The oil of claim 1 , wherein the amount of eicosapentaenoic acid, by weight, is from about 26% to about 38% of the total amount of docosahexaenoic acid and eicosapentaenoic acid, and the amount of docosahexaenoic acid, by weight, is from about 52% to about 64% of the total amount of docosahexaenoic acid and eicosapentaenoic acid.

5. The oil of claim 1 , wherein the amount of eicosapentaenoic acid, by weight, is from about 28% to about 36% of the total amount of docosahexaenoic acid and eicosapentaenoic acid, and the amount of docosahexaenoic acid, by weight, is from about 54% to about 62% of the total amount of docosahexaenoic acid and eicosapentaenoic acid.

6. A vegetable oil comprising omega-3 polyunsaturated fatty acids which comprise DHA and EPA in an amount of about >90%, by weight, of the total amount of omega-3 polyunsaturated fatty acids, and DPA n-3 is in an amount of from about 0% to about 10%, by weight, of the total amount of omega-3 polyunsaturated fatty acids, wherein the amount of EPA, by weight, is from about 28% to about 36% of the total amount of DHA and EPA, and the amount of DHA, by weight, is from about 54% to about 62% of the total amount of DHA and EPA, wherein said vegetable oil further comprising an effective amount of at least one added antioxidant.

7. A vegetable oil comprises omega-3 polyunsaturated fatty acids which comprise DHA and EPA in an amount of about >90%, by weight, of the total amount of omega-3 polyunsaturated fatty acids, and DPA n-3 is in an amount of from about 0% to about 2%, by weight, of the total amount of omega-3 polyunsaturated fatty acids, wherein the amount of EPA, by weight, is from about 10% to about 25% of the total amount of DHA and EPA, and the amount of DHA, by weight, is from about 75% to about 90% of the total amount of DHA and EPA, wherein said vegetable oil further comprising an effective amount of at least one added antioxidant.

Assignments (4)
CHANGE OF ASSIGNEE ADDRESS Recorded Sep 12, 2025
From: DSM IP ASSETS B.V.
To: DSM IP ASSETS B.V.
Reel/Frame 072873/0389 →
SECURITY INTEREST Recorded Oct 8, 2021
From: STAMPS.COM INC.; PSI SYSTEMS, INC.; AUCTANE LLC; SHIPPINGEASY GROUP, INC.
To: ARES CAPITAL CORPORATION
Reel/Frame 057758/0116 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 7, 2018
From: APT, KIRK E; BEHRENS, PAUL WARREN; HANSEN, JON MILTON; PFEIFER, JOSEPH W., III; STAHL, TRACEY LYNN; ZIRKLE, ROSS
To: DSM IP ASSETS B.V.
Reel/Frame 046661/0572 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 9, 2018
From: APT, KIRK E.; BEHRENS, PAUL WARREN; HANSEN, JON MILTON; PFEIFER, JOSEPH W., III; STAHL, TRACEY LYNN; ZIRKLE, ROSS
To: DSM IP ASSETS B.V.
Reel/Frame 045862/0706 →
Continuity (6)
Division 15481980 · Apr 7, 2017
Continuation 15198297 · Jun 30, 2016
Continuation 14698498 · Apr 28, 2015
Continuation 13554852 · Jul 20, 2012
Provisional Application 61510441 · Jul 21, 2011
Related Publication 20180169049A1 · Jun 21, 2018