IP Library Granted Patent US 11,220,715
Granted Patent B2
US 11,220,715 · App. 15/897,617 · Granted Jan 11, 2022

Gene expression markers for breast cancer prognosis

Inventors: Melody A. Cobleigh (Riverside, IL); Steven Shak (Hillsborough, CA); Joffre B. Baker (Montara, CA); Maureen T. Cronin (Los Altos, CA)
Assignee: Genomic Health, Inc.
C12Q1/6886C12Q2600/118C12Q2600/158
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Quick Facts
Patent No.
US 11,220,715
App. No.
15/897,617
Granted
Jan 11, 2022
Kind
B2
Abstract

The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer.

Claims (4)

1. A kit for predicting the likelihood of long-term survival of a breast cancer patient without the recurrence of breast cancer, the kit comprising a set of at least three oligonucleotides, wherein the at least three oligonucleotides comprise a nucleic acid molecule comprising the sequence of SEQ ID NO:339, a nucleic acid molecule comprising the sequence of SEQ ID NO:340, and a nucleic acid molecule comprising the sequence of SEQ ID NO:341 respectively, and wherein at least one oligonucleotide comprises at least one label.

2. The kit of claim 1 , further comprising at least one reagent for performing reverse transcriptase polymerase chain reaction (RT-PCR) using the at least three oligonucleotides.

3. The kit of claim 1 , wherein the at least one label comprises a fluorescent label and/or a quencher fluorescent label.

4. The kit of claim 3 , wherein the at least one label comprises both a fluorescent label and a quencher fluorescent label.

Assignments (2)
TERMINATION AND RELEASE OF SECURITY INTEREST IN PATENT RIGHTS (REEL/FRAME 69898/0380) Recorded Mar 27, 2026
From: JPMORGAN CHASE BANK, N.A.
To: GENOMIC HEALTH, INC.
Reel/Frame 075294/0821 →
PATENT SECURITY AGREEMENT Recorded Jan 14, 2025
From: GENOMIC HEALTH, INC.
To: JPMORGAN CHASE BANK, N.A.
Reel/Frame 069898/0380 →
Continuity (7)
Division 14257723 · Apr 21, 2014
Division 13473526 · May 16, 2012
Division 13221549 · Aug 30, 2011
Division 12478632 · Jun 4, 2009
Continuation 10758307 · Jan 14, 2004
Provisional Application 60440861 · Jan 15, 2003
Related Publication 20180230548A1 · Aug 16, 2018