Computer implemented identification of genetic similarity
A method, software, database and system for attribute partner identification and social network based attribute analysis are presented in which attribute profiles associated with individuals can be compared and potential partners identified. Connections can be formed within social networks based on analysis of genetic and non-genetic data. Degrees of attribute separation (genetic and non-genetic) can be utilized to analyze relationships and to identify individuals who might benefit from being connected.
1. A computing system comprising:
a first database containing genetic information of an individual;
a second database containing genetic information of a population of individuals;
a memory storing program instructions; and
a processor configured to execute the program instructions to carry out operations including:
obtaining, from the first database, the genetic information of the individual;
obtaining, from the second database, the genetic information of the population of individuals;
comparing genomic nucleotide sequences within the genetic information of the individual with genomic nucleotide sequences within the genetic information of the population of individuals, wherein the comparison determines respective degrees of overlap between the genomic nucleotide sequences of the individual and the genomic nucleotide sequences of the population of individuals;
calculating, based on the degrees of overlap, a subset of individuals from the population of individuals whose degrees of overlap are greater than a pre-determined threshold value;
transmitting, to a client device communicatively coupled to the computing system, a representation of a graphical user interface that identifies the subset of individuals as genetic relatives;
receiving, from the client device, a request to create an electronic connection invitation between the individual and at least one member of the subset of individuals identified as genetic relatives; and
establishing, based on an acceptance of the electronic connection invitation, a network between the individual and the at least one member of the subset of individuals identified as genetic relatives.
2. The system of claim 1 , the operations further comprising:
ranking the subset of individuals identified as genetic relatives according to their degrees of overlap, wherein the graphical user interface displays the rankings.
3. The system of claim 1 , the operations further comprising:
ranking the subset of individuals identified as genetic relatives according to genomic nucleotide segments shared between the individual and each of the subset of individuals, wherein the graphical user interface displays the rankings.
4. The system of claim 1 , the operations further comprising:
receiving, from the client device, a request to compare genomic nucleotide sequences between the individual and the at least one member of the network;
generating a comparison of genomic nucleotide sequences within the genetic information of the individual with genomic nucleotide sequences within the genetic information of the at least one member of the network; and
transmitting, to the client device, a representation of a further graphical user interface that represents the comparison of genomic nucleotide sequences within the genetic information of the individual with genomic nucleotide sequences within the genetic information of the at least one member of the network.
5. The system of claim 1 , the operations further comprising:
filtering the subset of individuals identified as genetic relatives based on non-genetic information of the subset of individuals.
6. The system of claim 1 , wherein the first database comprises the second database.
7. A computing system comprising:
a first database containing genetic information of an individual;
a second database containing genetic information of a population of individuals;
a memory storing program instructions; and
a processor configured to execute the program instructions to carry out operations including:
obtaining, from the first database, the genetic information of the individual;
obtaining, from the second database, the genetic information of the population of individuals;
comparing genomic nucleotide sequences within the genetic information of the individual with genomic nucleotide sequences within the genetic information of the population of individuals, wherein the comparison determines respective degrees of genetic similarity between the individual and one or more members of the population of individuals;
calculating, based on the degrees of genetic similarity, a subset of individuals from the population of individuals whose degrees of genetic similarity are greater than a pre-determined threshold value;
transmitting, to a client device communicatively coupled to the computing system, a representation of a graphical user interface that presents the subset of individuals as genetic relatives;
receiving, from the client device, a request to create an electronic connection invitation between the individual and at least one member of the subset of individuals identified as genetic relatives; and
establishing, based on an acceptance of the electronic connection invitation, a network between the individual and the at least one member of the subset of individuals identified as genetic relatives.
8. The system of claim 7 , the operations further comprising:
ranking the subset of individuals identified as genetic relatives based the degrees of genetic similarity.
9. The system of claim 7 , the operations further comprising:
filtering the subset of individuals identified as genetic relatives based on non-genetic attributes of the subset of individuals.
10. The system of claim 9 , wherein the filtering is based on one or more demographic attributes.
11. The system of claim 7 , the operations further comprising:
receiving, from the client device, a request to compare genomic nucleotide sequences between the individual and at least one member of the network;
generating a comparison of genomic nucleotide sequences within the genetic information of the individual with genomic nucleotide sequences within the genetic information of the at least one member of the network; and
transmitting, to the client device, a representation of a graphical user interface that represents the comparison of genomic nucleotide sequences within the genetic information of the individual with genomic nucleotide sequences within the genetic information of the at least one member of the network.
12. The system of claim 7 , wherein the first database comprises the second database.
13. A computing system comprising:
a first database containing genetic information of an individual;
a second database containing genetic information of a population of individuals;
a third database containing connection records indicating a genetic social network;
a memory storing program instructions; and
a processor configured to execute the program instructions to carry out operations including:
obtaining, from the first database, the genetic information of the individual;
obtaining, from the second database, the genetic information of the population of individuals;
comparing genomic nucleotide sequences within the genetic information of the individual with genomic nucleotide sequences within the genetic information of the population of individuals, wherein the comparison determines respective degrees of overlap between the genomic nucleotide sequences of the individual and the genomic nucleotide sequences of the population of individuals;
calculating, based on the degrees of overlap, a subset of individuals from the population of individuals whose degrees of overlap are greater than a pre-determined threshold value;
issuing, based on an instruction from the individual, an electronic invitation to one or more individuals of the subset of individuals to join the genetic social network;
generating, based on an acceptance of the electronic invitation by the one or more individuals, a set of electronic records for storage in the third database indicating membership of the one or more individuals in the genetic social network; and
transmitting, to a client device communicatively coupled to the computing system, a representation of a graphical user interface that identifies the degrees of overlap between the individual and the one or more individuals.
14. The system of claim 13 , the operations further comprising:
calculating, based on the degrees of overlap, a measure of family lineage between the individual and the one or more individuals, wherein the representation of the graphical user interface displays the measure of family lineage.
15. The system of claim 13 , the operations further comprising:
filtering the one or more individuals based on non-genetic attributes of the one or more individuals.
16. The system of claim 15 , wherein the filtering is based on one or more demographic attributes of the one or more individuals.
17. The system of claim 13 , wherein the first database comprises the second database and the third database.
18. A computing system comprising:
a first database containing genetic information of an individual;
a second database containing genetic information of a population of individuals;
a third database containing connection records indicating a genetic social network;
a memory storing program instructions; and
a processor configured to execute the program instructions to carry out operations including:
obtaining, from the first database, the genetic information of the individual;
obtaining, from the second database, the genetic information of the population of individuals;
comparing genomic nucleotide sequences within the genetic information of the individual with genomic nucleotide sequences within the genetic information of the population of individuals, wherein the comparison determines respective degrees of genetic similarity between the genomic nucleotide sequences of the individual and the genomic nucleotide sequences of the population of individuals;
calculating, based on the degrees of genetic similarity, a subset of individuals from the population of individuals whose degrees of genetic similarity are greater than a pre-determined threshold value;
issuing, based on an instruction from the individual, an electronic invitation to one or more individuals of the subset of individuals to join the genetic social network;
generating, based on an acceptance of the electronic invitation by the one or more individuals, a set of electronic records for storage in the third database indicating membership of the one or more individuals in the genetic social network; and
transmitting, to a client device communicatively coupled to the computing system, a representation of a graphical user interface that identifies the degrees of genetic similarity between the individual and the one or more individuals.
19. The system of claim 18 , the operations further comprising:
calculating, based on the degrees of generic similarity, a measure of family lineage between the individual and the one or more individuals, wherein the graphical user interface displays the measure of family lineage.
20. The system of claim 18 , the operations further comprising:
filtering the one or more individuals based on non-genetic attributes of the one or more individuals.
21. The system of claim 20 , wherein the filtering is based on one or more demographic attributes of the one or more individuals.