IP Library Granted Patent US 10,639,438
Granted Patent B2
US 10,639,438 · App. 15/936,251 · Granted May 5, 2020

Delivery devices

Inventors: Per Gisle Djupesland (Oslo, NO); Erik Andreassen (Oslo, NO); Rune Harald Gaarder (Oslo, NO); Christophe Péricé (Toulon, FR); Andreas Nilsson (Oslo, NO)
Assignee: OptiNose AS
A61M15/0098A61M11/006A61M11/06A61M15/002A61M15/0008A61M15/009A61M15/0021A61M15/0028A61M15/0031A61M15/0086A61M15/0091A61M15/08A61M2202/04
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Quick Facts
Patent No.
US 10,639,438
App. No.
15/936,251
Granted
May 5, 2020
Kind
B2
Abstract

A delivery device for delivering a metered amount of substance (L) in response to exhalation by a user, the delivery device comprising: a mouthpiece ( 5 ) through which the user in use exhales; an outlet ( 45 ) from which substance Is delivered; and a dispensing unit ( 35 ) which is operable to dispense a metered amount of substance through the outlet in response to exhalation by the user through the mouthpiece, wherein the dispensing unit comprises a body member ( 37 ) which includes a cavity ( 39 ) for containing a metered amount of substance, an outlet nozzle ( 43 ) which is fluidly connected to the cavity from which substance is in use delivered, and a dispensing ( 41 ) member which is movably disposed in the cavity and configured to be driven through the cavity by a driving pressure created by exhalation of the user, such as to cause substance to be delivered from the outlet nozzle.

Claims (28)

1. A delivery device for delivering a substance in response to exhalation by a user, the delivery device comprising:

a mouthpiece adapted for the user to exhale through;

an outlet from which the substance is delivered; and

a dispensing unit operable to dispense a metered amount of the substance through the outlet in response to exhalation by the user through the mouthpiece, wherein the dispensing unit comprises a body member, the body member including a cavity containing the substance, an outlet nozzle fluidly connected to the cavity from which the substance is delivered, and a dispensing member movably disposed in the cavity and configured to be driven through the cavity by a driving pressure created by the exhalation of the user, causing the metered amount of the substance to be delivered from the outlet nozzle;

whereby the exhalation by the user creates an exhalation flow adapted to directly act on the dispensing member.

2. The delivery device of claim 1 , wherein the cavity is an elongate cavity.

3. The delivery device of claim 2 , wherein the cavity has a cylindrical section and the dispensing member comprises a ball.

4. The delivery device of claim 3 , wherein the ball sealingly engages an inner peripheral wall of the cavity.

5. The delivery device of claim 1 , wherein the dispensing member is configured to move within the cavity when the driving pressure is less than 5 kPa.

6. The delivery device of claim 1 , wherein the outlet nozzle is configured to deliver an aerosol spray.

7. The delivery device of claim 6 , wherein the outlet nozzle provides for a rectilinear flow for a distance of at least 30 mm from an exit of the outlet nozzle.

8. The delivery device of claim 1 , wherein the outlet nozzle is configured to deliver a jet.

9. The delivery device of claim 1 , further comprising a pressure regulator fluidly connected to the dispensing unit and configured to apply a predeterminable driving pressure to the dispensing member.

10. The delivery device of claim 1 , further comprising a housing defining a fluid communication path between the mouthpiece and the outlet.

11. The delivery device of claim 10 , further comprising a baffle member disposed in the fluid communication path.

12. The delivery device of claim 11 , wherein the baffle member includes a first, driving air pressure channel fluidly connected to the dispensing unit and at least one second, entraining air flow channel fluidly connected to the mouthpiece through which an entraining air flow is delivered for entraining the substance as delivered by the dispensing unit.

13. The delivery device of claim 12 , wherein the baffle member includes a plurality of entraining air flow channels.

14. The delivery device of claim 11 , wherein the housing includes an inlet chamber upstream of the baffle member and downstream of the mouthpiece which flares outwardly from the mouthpiece toward the baffle member.

15. The delivery device of claim 11 , wherein the housing includes an outlet chamber downstream of the baffle member.

16. The delivery device of claim 15 , wherein the outlet chamber surrounds the dispensing unit.

17. The delivery device of claim 16 , further comprising:

an annulus surrounding the outlet nozzle of the dispensing unit and positioned radially between the dispensing unit and the housing.

18. The delivery device of claim 17 , wherein the annulus includes a plurality of flow apertures.

19. The delivery device of claim 1 , wherein the outlet includes a flow restrictor.

20. The delivery device of claim 19 , wherein the flow restrictor tapers inwardly.

21. The delivery device of claim 20 , wherein the flow restrictor has a frusto-conical section.

22. The delivery device of claim 1 , where the delivery device is configured to deliver a liquid.

23. The delivery device of claim 1 , wherein the outlet is a nosepiece and the delivery device is a nasal delivery device for delivering the substance to a nasal airway of the user.

Assignments (8)
RELEASE OF SECURITY INTEREST IN PATENTS RECORDED AT REEL/FRAME 71337/0132 Recorded Mar 17, 2026
From: OAKTREE FUND ADMINISTRATION, LLC
To: OPTINOSE, INC.
Reel/Frame 075101/0804 →
PATENT SECURITY AGREEMENT Recorded Mar 16, 2026
From: OPTINOSE, INC.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT
Reel/Frame 075111/0018 →
SECURITY INTEREST Recorded May 22, 2025
From: OPTINOSE, INC.
To: OAKTREE FUND ADMINISTRATION, LLC
Reel/Frame 071337/0132 →
RELEASE OF SECURITY INTEREST Recorded May 21, 2025
From: BIOPHARMA CREDIT PLC, AS COLLATERAL AGENT
To: OPTINOSE INC.
Reel/Frame 071547/0979 →
CHANGE OF ADDRESS Recorded Jan 8, 2025
From: OPTINOSE, INC.
To: OPTINOSE, INC.
Reel/Frame 069848/0226 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 27, 2022
From: OPTINOSE AS
To: OPTINOSE INC
Reel/Frame 061546/0424 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 14, 2020
From: ANDREASSEN, ERIK; PERICE, CHRISTOPHE; NILSSON, ANDREAS; GAARDER, RUNE HARALD; DJUPESLAND, PER GISLE
To: OPTINOSE AS
Reel/Frame 051509/0759 →
SECURITY INTEREST Recorded Sep 13, 2019
From: OPTINOSE AS
To: BIOPHARMA CREDIT PLC, AS COLLATERAL AGENT
Reel/Frame 050371/0913 →
Cited By (1)
US 12,539,387