IP Library Granted Patent US 10,610,541
Granted Patent B2
US 10,610,541 · App. 15/941,012 · Granted Apr 7, 2020

Prebiotics

Inventor: Giorgio Dell'Acqua (Jersey City, NJ)
Assignee: VANTAGE SPECIALTIES, INC.
A61K31/716A61K9/0014A61K9/5015A61K9/5047
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Quick Facts
Patent No.
US 10,610,541
App. No.
15/941,012
Granted
Apr 7, 2020
Kind
B2
Abstract

A composition which comprises a prebiotic or a mixture thereof that, upon application to an individual's skin, has a beneficial effect on the skin and that is incorporated in the composition in the form of a multiplicity of tiny beads which comprise, in addition to the prebiotic, a matrix-forming agent, for example, mannitol and hydroxypropyl methylcellulose, and a filler, for example, microcrystalline cellulose, and a personal care composition which includes the beads.

Claims (42)

1. A composition consisting essentially of: (A) a prebiotic or a mixture thereof; and (B) one or more other ingredients that function to render the composition suitable for use as a delivery agent to the skin of an individual; and that, upon application to the individual's skin, has a beneficial effect on the skin; said prebiotic being incorporated in the composition in the form of a multiplicity of tiny beads having a diameter within the range of about 425 to about 1000 microns.

2. A composition according to claim 1 including a matrix-forming agent.

3. A composition according to claim 1 including a filler.

4. A composition according to claim 1 including spherical beads.

5. A composition according to claim 3 including a matrix-forming agent having a soft flowable texture which functions to permit the beads to be spread readily on the skin's surface.

6. A composition according to claim 1 comprising:

(A) about 0.0001 to about 50 wt. % of prebiotic(s);

(B) about 30 to about 75 wt. % of a matrix-forming agent; and

(C) about 15 to about 45 wt. % of filler.

7. A composition according to claim 1 comprising:

(A) about 0.0001 to about 50 wt. % of prebiotic(s);

(B) about 30 to about 65 wt. % of softening agent;

(C) about 0.5 to about 10 wt. % of adhesive; and

(D) about 15 to about 45 wt. % of a filler.

8. A composition according to claim 1 comprising:

(A) about 1 to about 50 wt. % of prebiotic(s);

(B) about 30 to about 65 wt. % of mannitol;

(C) about 0.5 to about 10 wt. % of hydroxypropyl methylcellulose; and

(D) about 15 to about 45 wt. % of microcrystalline cellulose.

9. A composition according to claim 6 in the form of spherical beads having a diameter within the range of about 425 to about 1000 microns.

10. A composition according to claim 7 in the form of spherical beads having a diameter within the range of about 425 to about 1000 microns.

11. A composition according to claim 8 in the form of spherical beads having a diameter within the range of about 425 to about 1000 microns.

12. An aqueous composition according to claim 1 including at least about 15 wt. % water and about 0.5 to about 3 wt. % of said beads which are not soluble in the water.

13. A method for forming a multiplicity of micro beads having a diameter within the range of about 425 to about 1000 microns comprising forming a mixture of powdery ingredients comprising: (A) a prebiotic; (B) a matrix-forming agent; and (C) a filler; adding to said mixture water and forming therefrom a wet blend of the ingredients; forming the wet blend of ingredients into spherically shaped wet beads, and recovering said micro beads after drying said wet beads.

14. A composition comprising at least about 15 wt. % water, about 0.5 to about 3 wt. % of beads according to claim 1 , and ingredients which are effective for use in a personal care composition, said personal care composition being in the form of a cosmetic, liquid soap, shower gel, body wash, shampoo, or moisturizing face cream.

15. A composition according to claim 1 in which the beads are not soluble in water.

16. A composition according to claim 1 wherein the composition contains no more than about 0.1 wt. % of a probiotic.

17. A composition according to claim 1 which is free of a probiotic.

18. A composition according to claim 14 in which the beads are spherical and comprise:

(A) about 0.0001 to about 50 wt. % of said prebiotic(s);

(B) about 30 to about 75 wt. % of a matrix-forming agent; and

(C) about 15 to about 45 wt. % of said filler.

19. A composition according to claim 14 in which the beads are spherical and comprise:

(A) about 0.0001 to about 50 wt. % of said prebiotic(s);

(B) about 30 to about 65 wt. % of a softening agent;

(C) about 0.5 to about 10 wt. % of an adhesive; and

(D) about 15 to about 45 wt. % of a filler.

20. A composition according to claim 14 in which the beads are spherical and comprise:

(A) about 1 to about 50 wt. % of said prebiotic(s);

(B) about 30 to about 65 wt. % of mannitol;

(C) about 0.5 to about 10 wt. % of hydroxypropyl methylcellulose; and

(D) about 15 to about 45 wt. % of microcrystalline cellulose.

Assignments (6)
PATENT SECURITY AGREEMENT Recorded Sep 4, 2025
From: VANTAGE SPECIALTIES, INC.; VANTAGE SPECIALTY CHEMICALS, INC.; VANTAGE SPECIALTY INGREDIENTS, INC.
To: APOLLO ADMINISTRATIVE AGENCY LLC, AS ADMINISTRATIVE AGENT AND COLLATERAL AGENT
Reel/Frame 072801/0720 →
TERMINATION AND RELEASE OF FIRST SECURITY INTEREST IN PATENTS RECORDED AT REEL 052649, FRAME 0429 Recorded Aug 29, 2025
From: MORGAN STANLEY SENIOR FUNDING, INC., AS COLLATERAL AGENT
To: VANTAGE SPECIALTIES, INC.
Reel/Frame 072761/0611 →
TERMINATION AND RELEASE OF SECURITY INTEREST IN SECOND LIEN PATENT SECURITY AGREEMENT RECORDED AT REEL 052649, FRAME 0377 Recorded Mar 14, 2023
From: MORGAN STANLEY SENIOR FUNDING, INC., AS COLLATERAL AGENT
To: VANTAGE SPECIALTIES, INC.
Reel/Frame 063085/0205 →
SECOND LIEN PATENT SECURITY AGREEMENT Recorded May 13, 2020
From: VANTAGE SPECIALTIES, INC.
To: MORGAN STANLEY SENIOR FUNDING, INC.
Reel/Frame 052649/0377 →
FIRST LIEN PATENT SECURITY AGREEMENT Recorded May 13, 2020
From: VANTAGE SPECIALTIES, INC.
To: MORGAN STANLEY SENIOR FUNDING, INC.
Reel/Frame 052649/0426 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 25, 2020
From: DELL'ACQUA, GIORGIO
To: VANTAGE SPECIALTIES, INC.
Reel/Frame 051918/0332 →