Isothiocyanate functional surfactant and associated method of use
A method for treating phytophotodermatitis including the steps of applying an isothiocyanate functional surfactant to an area affected by phytophotodermatitis, wherein said isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
1. An isothiocyanate functional surfactant, comprising:
a lysine derivative, wherein the lysine derivative comprises an α-nitrogen and a ε-nitrogen, and wherein an alkanoyl substituent comprising 8 carbon atoms is bound to the α-nitrogen, and further wherein the ε-nitrogen forms part of an isothiocyanate functional group.
2. The isothiocyanate functional surfactant according to claim 1 , in combination with an additional surfactant selected from at least one of the group comprising a non-ionic surfactant, an anionic surfactant, a cationic surfactant, a zwitterionic surfactant, and combinations thereof.
3. The isothiocyanate functional surfactant according to claim 2 , wherein the additional surfactant comprises a non-ionic surfactant.
4. The isothiocyanate functional surfactant according to claim 3 , wherein the non-ionic surfactant is selected from at least one of the group comprising alcohols, alkanolamides, amine oxides, esters, glycerides, ethoxylated glycerides, polyglyceryl esters, sorbitan esters, carbohydrate esters, ethoxylated carboxylic acids, phosphoric acid triesters, ethers, ethoxylated alcohols, alkyl glucosides, ethoxylated polypropylene oxide ethers, alkylated polyethylene oxides, alkylated polypropylene oxides, alkylated PEG/PPO copolymers, and combinations thereof.
5. The isothiocyanate functional surfactant according to claim 1 , wherein the additional surfactant comprises an anionic surfactant.
6. The isothiocyanate functional surfactant according to claim 5 , wherein the anionic surfactant is selected from at least one of the group comprising taurates, isethionates, alkyl sulfates, alkyl ether sulfates, succinamates, alkyl sulfonates, alkylaryl sulfonates, olefin sulfonates, alkoxy alkane sulfonates, salts of fatty acids derived from natural plant and/ or animal sources and/or synthetically prepared, alkylated ammonium salts of alkylated and/or acylated amino acids and/or peptides, alkylated sulfoacetates, alkylated sulfosuccinates, acylglyceride sulfonates, alkoxyether sulfonates, phosphoric acid esters, phospholipids, and combinations thereof.
7. The isothiocyanate functional surfactant according to claim 1 , wherein the additional surfactant comprises a cationic surfactant.
8. The isothiocyanate functional surfactant according to claim 7 , wherein the cationic surfactant is selected from at least one of the group comprising alkylated quaternary ammonium salts R 4 NX, alkylated amino-amides (RCONH—(CH 2 ) n )NR 3 X, alkylimidazolines, alkoxylated amines, and combinations thereof.
9. The isothiocyanate functional surfactant according to claim 1 , wherein the additional surfactant comprises a zwitterionic surfactant.
10. The isothiocyanate functional surfactant according to claim 9 , wherein the zwitterionic surfactant is selected from at least one of the group comprising betaines, sultaines, hydroxysultaines, amido betaines, amidosulfo betaines, and combinations thereof.