Microfemtotomy methods and systems
Methods and systems for performing laser-assisted surgery on an eye form one or more small anchoring capsulotomies in the lens capsule of the eye. The one or more anchoring capsulotomies are configured to accommodate corresponding anchoring features of an intraocular lens and/or to accommodate one or more drug-eluting members. A method for performing laser-assisted eye surgery on an eye having a lens capsule includes forming an anchoring capsulotomy in the lens capsule and coupling an anchoring feature of the intraocular lens with the anchoring capsulotomy. The anchoring capsulotomy is formed by using a laser to incise the lens capsule. The anchoring feature can protrude transverse to a surface of the intraocular lens that interfaces with the lens capsule adjacent to the anchoring capsulotomy.
1. A method for performing a laser-assisted treatment of an eye having a lens capsule, the method comprising:
forming an anchoring capsulotomy in the lens capsule by using a laser to incise the lens capsule, the anchoring capsulotomy being configured to accommodate a drug eluting plug; and
removably coupling the drug eluting plug to the anchoring capsulotomy, wherein the drug-eluting plug includes at least one cap on a body, wherein a portion of the body of the drug eluting plug is removably fitted through the anchoring capsulotomy to retain the drug eluting plug's position relative to the lens capsule, wherein the portion the body of the drug-eluting plug that passes through the anchoring capsulotomy includes pores configured for dispersion of a drug which is otherwise contained within the drug-eluting plug.
2. The method of claim 1 , wherein the drug eluting plug is configured to time-release a drug or therapeutic agent, wherein the drug or therapeutic agent includes one or more of glaucoma medications, anti-vascular endothelial growth factor (VEGF) treatments, diclofenac sodium, ketorolac tromethamine, or cytotoxic LEC-specific genes.
3. The method of claim 1 , further comprising:
forming a central capsulotomy in the lens capsule by using the laser to incise the lens capsule,
wherein the anchoring capsulotomy is adjacent to the central capsulotomy.
4. The method of claim 1 , wherein the body of the drug-eluting plug has an end opposite the cap.
5. The method of claim 4 , wherein the cap has an outer diameter of 0.5-4.0 mm and a thickness of 0.1-1.0 mm, the body has an outer diameter of 1.0-3.0 mm and a length of 1.0-3.0 mm, and the end has a radius of curvature of 0.125-4.0 mm.
6. The method of claim 1 , wherein the body has a waist configured to engage within the anchoring capsulotomy.
7. The method of claim 1 , wherein the anchoring capsulotomy has a buttonhole shape.
8. The method of claim 1 , wherein the drug-eluting plug includes two caps located on two opposite ends of the body, the two caps being configured to retain the drug-eluting plug within the anchoring capsulotomy.
9. The method of claim 1 , wherein the step of forming an anchoring capsulotomy includes forming a plurality of anchoring capsulotomies, wherein the anchoring capsulotomies are formed in an anterior capsule of the eye, or in a posterior capsule of the eye, or in both the anterior and posterior capsules.