IP Library Granted Patent US 10,568,872
Granted Patent B2
US 10,568,872 · App. 15/968,692 · Granted Feb 25, 2020

Antifungal compounds

Inventors: Jonathan A. Covel (San Diego, CA); Mitchell Mutz (San Diego, CA); Peter J. Webb (San Diego, CA); Robert Remme Webb (San Diego, CA)
Assignee: Duke University
A61K31/436A61K31/01A61K31/131A61K31/407A61K31/4164A61K31/4192A61K31/4196A61K31/425A61K31/437A61K31/497A61K31/5377A61K31/685A61K31/695A61K45/06
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Quick Facts
Patent No.
US 10,568,872
App. No.
15/968,692
Granted
Feb 25, 2020
Kind
B2
Abstract

The technical field of the invention is in pharmaceutical compounds and methods. In an aspect, the disclosure provides macrolide compounds suitable for use as antifungal agents, as well as methods for their use and compositions containing the same.

Claims (2)

1. A compound selected from the group consisting of compounds 2-37, 39-91, 96-155, 157-158, 160-164, 167-190, 193, 200, 202-213, 215, 217, 218, and 219 as recited in Table 1.

2. A pharmaceutical composition comprising a formulation according to claim 1 in effective unit dosage.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 6, 2018
From: COVEL, JONATHAN A.; MUTZ, MITCHELL; WEBB, PETER J.; WEBB, ROBERT REMME
To: AMPLYX PHARMACEUTICALS, INC.
Reel/Frame 047222/0052 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 24, 2018
From: AMPLYX PHARMACEUTICALS, INC.
To: DUKE UNIVERSITY
Reel/Frame 046441/0598 →
Continuity (4)
Continuation 15207384 · Jul 11, 2016
Continuation PCTUS2015011247 · Jan 13, 2015
Provisional Application 61926413 · Jan 13, 2014
Related Publication 20190000814A1 · Jan 3, 2019
Cited By (2)
US 12,558,356 US 12,594,275