Detecting and treating disordered breathing
A system for treating disordered breathing of a human being includes an implantable transvenous stimulation lead having at least one stimulation electrode and a sensor configured to detect activity level of the human being. The system includes an energy source, a pulse generator and circuitry, the circuitry operative to receive a signal indicative of the activity level of the human being from the sensor, wherein the circuitry is configured to cause the energy source and the pulse generator to deliver spaced apart stimulation signals to the at least one stimulation electrode while the activity level of the human being is sufficiently low to be indicative of sleep. Spaced apart stimulation pulses from the electrode are configured to extend a duration of a time of at least one breath being defined as the time from an onset of inhalation to the onset of inhalation of a successive breath.
1. A system for treating disordered breathing of a human being comprising:
a stimulation lead having at least one stimulation electrode, wherein the stimulation lead is configured to be implanted into a blood vessel proximate a phrenic nerve, wherein the at least one stimulation electrode is configured to electrically stimulate the phrenic nerve;
a sensor configured to detect activity level of the human being; and
an energy source, a pulse generator and circuitry, the circuitry operative to receive a signal indicative of the activity level of the human being from the sensor, wherein the circuitry is configured to:
cause detection of a hyperpnea episode based on a respiration signal;
cause the energy source and the pulse generator to trigger and/or terminate a train of stimulation pulses to the at least one stimulation electrode based on the activity level of the human being indicative of sleep,
wherein the train of stimulation pulses is initiated during the detected hyperpnea episode,
wherein stimulation pulses in the train of stimulation pulses are substantially uniformly spaced in time, and
wherein the energy source and the at least one stimulation electrode are configured to deliver the train of stimulation pulses, the train of stimulation pulses configured to extend a duration of time of at least one breath, the at least one breath being defined as a time from an onset of inhalation to the onset of inhalation of a successive breath.
2. The system of claim 1 , wherein the sensor configured to detect activity level comprises an accelerometer configured to detect the activity level of the human being.
3. The system of claim 1 , wherein the sensor configured to detect activity level comprises an accelerometer configured to detect the activity level of the human being, and the accelerometer also is configured to sense respiration of the human being and provide the respiration signal.
4. The system of claim 1 and further comprising a respiration sensor wherein the circuitry is configured to determine a duration of a Cheyne-Stokes Respiration (CSR) episode based on the respiration signal from the respiration sensor, wherein the circuitry is configured to deliver a stimulation signal to the stimulation electrode during the Cheyne-Stokes Respiration (CSR) episode while the sensor configured to detect activity level of the human being is sending a signal to the circuitry indicative of the activity level of the human being at a level indicative of sleep.
5. The system of claim 4 , wherein the train of stimulation pulses are substantially uniformly spaced in time and are delivered throughout the duration of the Cheyne-Stokes Respiration (CSR) episode.
6. The system of claim 4 wherein each simulation pulse in the train of stimulation pulses is in a range of one to two seconds.
7. The system of claim 4 , wherein the respiration sensor senses transthoracic impedance.
8. A system for treating disordered breathing of a human being comprising:
a stimulation lead having at least one stimulation electrode wherein the lead is configured to be located in a vein proximate a phrenic nerve, such that the at least one stimulation electrode is configured to transvenously capture the phrenic nerve;
a respiration sensor;
a sensor configured to detect sleep by the human being; and
an energy source, a pulse generator and circuitry, the circuitry operative to receive a signal indicative of a position or activity level of the human being from the sensor configured to detect sleep, and wherein the circuitry is configured to:
cause detection of a hyperpnea episode based on a signal from the respiration sensor;
cause the energy source and the pulse generator to trigger and/or terminate a train of stimulation pulses to the at least one stimulation electrode based on the detected sleep;
wherein the train of stimulation pulses is initiated during the detected hyperpnea episode;
wherein stimulation pulses in the train of stimulation pulses are substantially uniformly spaced in time and delivered by the at least one stimulation electrode during the detected hyperpnea episode to extend a duration of time of at least one breath, the at least one breath being defined as a time from an onset of inhalation to the onset of inhalation of a successive breath.
9. The system of claim 8 , wherein the sensor configured to detect sleep comprises an accelerometer configured to detect movement of the human being.
10. The system of claim 8 , wherein the train of stimulation pulses is delivered throughout a duration of the detected hyperpnea episode.
11. The system of claim 10 , wherein each stimulation pulse in the train of stimulation pulses is in the range of one to two seconds.
12. The system of claim 8 , wherein the respiration sensor senses transthoracic impedance.