Stable pharmaceutical composition and methods of using same
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
1. A pharmaceutical composition comprising eicosapentaenoic acid and docosapentaenoic acid, wherein the eicosapentaenoic acid is present in an amount of about 70% to about 90%, by weight, of all fatty acids present in the pharmaceutical composition, the docosapentaenoic acid is present in an amount of up to about 10%, by weight, of all fatty acids in the pharmaceutical composition and the pharmaceutical composition is substantially free of docosahexaenoic acid.
2. The pharmaceutical composition of claim 1 , wherein the docosapentaenoic acid is present in an amount up to about 5%, by weight, of all fatty acids present in the pharmaceutical composition.
3. The pharmaceutical composition of claim 1 , wherein the docosapentaenoic acid is present in an amount of about 5%, by weight, of all fatty acids present in the pharmaceutical composition.
4. The pharmaceutical composition of claim 1 , wherein the pharmaceutical composition is free of docosahexaenoic acid.
5. The pharmaceutical composition of claim 1 further comprising heneicosapentaenoic acid.
6. The pharmaceutical composition of claim 5 , wherein the pharmaceutical composition is encapsulated in a capsule shell.
7. The pharmaceutical composition of claim 2 further comprising heneicosapentaenoic acid.
8. The pharmaceutical composition of claim 7 , wherein the pharmaceutical composition is encapsulated in a capsule shell.