IP Library Granted Patent US 11,003,694
Granted Patent B2
US 11,003,694 · App. 15/999,198 · Granted May 11, 2021

Learning systems for pangenetic-based recommendations

Inventors: Andrew Alexander Kenedy (Sugar Land, TX); Charles Anthony Eldering (Doylestown, PA)
Assignee: Expanse Bioinformatics
G06F16/285G06F16/2237G06F16/951G06F16/9535
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Quick Facts
Patent No.
US 11,003,694
App. No.
15/999,198
Granted
May 11, 2021
Kind
B2
Abstract

An embodiment may involve storing, by a computing device and in a database, a set of pangenetic attributes of a set of individuals, wherein the pangenetic attributes of the set are respectively and statistically associated with products; based on the statistical associations between the pangenetic attributes and the products, determining, by the computing device, product recommendations for a second set of individuals; receiving, by the computing device and from the second set of individuals, a plurality of measures of satisfaction with the product recommendations; based on the plurality of measures of satisfaction, learning, by the computing device, an association between a subset of the pangenetic attributes and a particular product; and storing, by the computing device and in the database, the learned association, wherein the learned association provides a basis for subsequent recommendations of the particular product when a subsequent individual exhibits the subset of the pangenetic attributes.

Claims (45)

1. A computer-implemented method comprising:

storing, by a computing device of a computer and in a database accessible to the computing device, a set of pangenetic attributes of a set of individuals and a set of non-pangenetic attributes of the set of individuals, wherein the pangenetic attributes of the set are respectively and statistically associated with products via a set of statistical associations;

based on the set of statistical associations between the pangenetic attributes and the products, determining, by the computing device, product recommendations for a second set of individuals;

receiving, by the computing device and from the second set of individuals, a plurality of measures of satisfaction with the product recommendations;

based on the plurality of measures of satisfaction, learning, by the computing device, an association between (i) a set of core attributes comprising a subset of the pangenetic attributes and a subset of the non-pangenetic attributes, and (ii) a particular product of the products, wherein the set of core attributes are associated with the plurality of measures of satisfaction and the particular product;

storing, by the computing device and in the database, the learned association between the set of core attributes and the particular product, wherein the learned association provides a basis for subsequent recommendations of the particular product when a subsequent individual exhibits the subset of the pangenetic attributes;

receiving a representation of the subset of the pangenetic attributes;

storing, in the database and associated with a particular individual, the representation of the subset of the pangenetic attributes;

receiving a request for a product recommendation for the particular individual; and

in response to the subset of the pangenetic attributes being associated with the particular individual and the request for the product recommendation, providing a recommendation of the particular product.

2. The computer-implemented method of claim 1 , wherein the subset of the pangenetic attributes is one or more single nucleotide polymorphisms (SNPs).

3. The computer-implemented method of claim 1 , wherein the measures of satisfaction are from an ordered scale of two or more values.

4. The computer-implemented method of claim 1 , wherein the subset of the pangenetic attributes are associated with a phenotype, and wherein one or more of the measures of satisfaction indicate that the particular product is favorable to individuals exhibiting the phenotype.

5. The computer-implemented method of claim 1 , wherein the measures of satisfaction are stored in a two-dimensional item feedback matrix that maps instances of the measures of satisfaction from specific individuals to specific products.

6. The computer-implemented method of claim 1 , further comprising:

based on the measures of satisfaction, identifying a first individual of the second set of individuals and a second individual of the second set of individuals as a pangenetic cluster; and

predicting a preference of the second individual for the particular product based on a measure of satisfaction that the first individual has related to the particular product.

7. The computer-implemented method of claim 1 , wherein one or more of the set of pangenetic attributes are stored in a masked fashion to prevent access by unauthorized parties.

8. A computer-implemented method comprising:

receiving, by a computing device of a computer, a request related to a particular individual, wherein a database accessible to the computing device stores: (i) a set of pangenetic attributes of a set of individuals, the pangenetic attributes of the set respectively and statistically associated with products, (ii) a set of non-pangenetic attributes of the set of individuals, and (iii) a learned association between a subset of the pangenetic attributes and a subset of the non-pangenetic attributes therein forming a set of core attributes, and a particular product of the products, the learned association based on a plurality of measures of satisfaction with product recommendations that were received from the set of individuals, wherein the request includes a representation of the subset of the pangenetic attributes;

storing, by the computing device and in the database, the representation of the subset of the pangenetic attributes as associated with the particular individual;

based on at least some of the set of pangenetic attributes and the plurality of measures of satisfaction, identifying that a second particular individual is in a pangenetic cluster with the particular individual;

predicting a preference of the particular individual for the particular product based on a measure of satisfaction that the second particular individual has related to the particular product;

receiving a request for a product recommendation for the particular individual; and

based on the preference as predicted and the request for the product recommendation, providing a recommendation of the particular product.

9. The computer-implemented method of claim 8 , wherein the measures of satisfaction are from an ordered scale of two or more values.

10. The computer-implemented method of claim 8 , wherein the measures of satisfaction are stored in a two-dimensional item feedback matrix that maps instances of the measure of satisfaction from specific individuals to specific products.

11. A non-transitory computer-readable medium containing program instructions that, when executed by a processor of a computing device, cause the computing device to perform operations comprising:

storing, in a database accessible to the computing device, a set of pangenetic attributes of a set of individuals, wherein the pangenetic attributes of the set are respectively and statistically associated with products via a set of statistical associations, and a set of non-pangenetic attributes of the set of individuals;

based on the set of statistical associations between the pangenetic attributes and the products, determining product recommendations for a second set of individuals;

receiving, from the second set of individuals, a plurality of measures of satisfaction with the product recommendations;

based on the plurality of measures of satisfaction, learning an association between a subset of the pangenetic attributes, a subset of the non-pangenetic attributes, and a particular product of the products, therein forming a set of core attributes, wherein the set of core attributes are associated with the plurality of measures of satisfaction and the particular product;

storing, in the database, the learned association, wherein the learned association provides a basis for subsequent recommendations of the particular product when a subsequent individual exhibits the subset of the pangenetic attributes;

receiving a representation of the subset of the pangenetic attributes;

storing, in the database and associated with a particular individual, the representation of the subset of the pangenetic attributes;

receiving a request for a product recommendation for the particular individual; and

in response to the subset of the pangenetic attributes being associated with the particular individual and the request for the product recommendation, providing a recommendation of the particular product.

12. The non-transitory computer-readable medium of claim 11 , wherein the subset of the pangenetic attributes is one or more single nucleotide polymorphisms (SNPs).

13. The non-transitory computer-readable medium of claim 11 , wherein the measures of satisfaction are from an ordered scale of two or m ore values.

14. The non-transitory computer-readable medium of claim 11 , wherein the subset of the pangenetic attributes are associated with a phenotype, and wherein one or more of the measures of satisfaction indicate that the particular product is favorable to individuals exhibiting the phenotype.

15. The non-transitory computer-readable medium of claim 11 , wherein the measures of satisfaction are stored in a two-dimensional item feedback matrix that maps instances of the measures of satisfaction from specific individuals to specific products.

16. The non-transitory computer-readable medium of claim 11 , the operations further comprising:

based on the measures of satisfaction, identifying a first individual of the second set of individuals and a second individual of the second set of individuals as a pangenetic cluster; and

predicting a preference of the second individual for the particular product based on a measure of satisfaction that the first individual has related to the particular product.

17. The non-transitory computer-readable medium of claim 11 , wherein one or more of the set of pangenetic attributes are stored in a masked fashion to prevent access by unauthorized parties.

Assignments (8)
CORRECTIVE ASSIGNMENT TO CORRECT THE APP. NO. 63806415 TO 63806145 AND APPL NO. 17721779 TO 17731779 PREVIOUSLY RECORDED ON REEL 73168 FRAME 531. ASSIGNOR(S) HEREBY CONFIRMS THE CHANGE OF NAME. Recorded Jan 6, 2026
From: 23ANDME PGS LLC
To: 23ANDME GENOMICS LLC
Reel/Frame 074434/0334 →
CHANGE OF NAME Recorded Oct 22, 2025
From: 23ANDME PGS LLC
To: 23ANDME GENOMICS LLC
Reel/Frame 073168/0531 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 26, 2025
From: 23ANDME, INC.
To: 23ANDME PGS LLC
Reel/Frame 072562/0795 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE ADDRESS PREVIOUSLY RECORDED AT REEL: 058554 FRAME: 0021. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT . Recorded Jan 7, 2022
From: EXPANSE BIOINFORMATICS, INC.
To: 23ANDME, INC.
Reel/Frame 058982/0739 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 5, 2022
From: EXPANSE BIOINFORMATICS, INC.
To: 23ANDME, INC.
Reel/Frame 058554/0021 →
CHANGE OF ADDRESS BY ASSIGNEE Recorded Apr 5, 2021
From: EXPANSE BIOINFORMATICS, INC.
To: EXPANSE BIOINFORMATICS, INC.
Reel/Frame 055824/0529 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE NAME PREVIOUSLY RECORDED AT REEL: 055474 FRAME: 0446. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Mar 26, 2021
From: KENEDY, ANDREW A.; ELDERING, CHARLES A.
To: EXPANSE BIOINFORMATICS, INC.
Reel/Frame 055743/0058 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 3, 2021
From: KENEDY, ANDREW A.; ELDERING, CHARLES A.
To: EXPANSE BIOINFORMATICS
Reel/Frame 055474/0446 →
Continuity (4)
Continuation 14708415 · May 11, 2015
Continuation 13361533 · Jan 30, 2012
Continuation 12346738 · Dec 30, 2008
Related Publication 20190005113A1 · Jan 3, 2019
Cited By (8)
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