Air detection system and method for detecting air in a pump of an infusion system
Various systems and methods for detecting air in a chamber of an infusion system are disclosed. In one embodiment, a determination is made that air is contained in the chamber on the basis of a change in the average force exerted against the plunger utilizing a derivative spike for event detection and a systematic reduction in the average force to confirm the nature of the change. In another embodiment, a determination is made that the chamber contains air when a difference between the current force profile and a baseline force profile crosses a threshold. In an additional embodiment, a force profile is classified as being an air force profile or a liquid force profile based on extracted features of the force profile.
1. A system for detecting air in a chamber of an infusion system, the infusion system comprising a pump and a plunger moveably disposed against the chamber, the chamber configured to hold fluid, the system comprising:
an actuator device configured to move the plunger against the chamber;
a sensor configured to detect a force acting on the plunger as it moves against the chamber; and
one or more hardware processors configured to:
determine a change in force per unit volume of the fluid at a first time during infusion;
determine the change in force per unit volume satisfies a threshold at the first time;
determine a difference between a first average force acting on the plunger prior to the first time and a second average force acting on the plunger after a delay time from the first time;
determine the difference satisfies a force differential; and
detect a presence of air in the chamber based on the determination of the difference satisfying the force differential and the determination of the change in force satisfying the threshold.
2. The system of claim 1 , wherein the determination of the change in force per unit volume satisfying the threshold further comprises determining the change in force per unit volume crosses the threshold more than once in a time period after the first time, wherein the time period is less than or equal to the delay time.
3. The system of claim 1 , wherein the change in force per unit volume comprises a change in derivative of force with respect to per unit volume.
4. The system of claim 1 , wherein the delay time is measured with respect to volume of fluid delivered.
5. A system for detecting air in a chamber of an infusion system, the infusion system comprising a pump and a plunger moveably disposed against the chamber, the chamber configured to hold fluid, the system comprising one or more hardware processors configured to:
receive a measurement of force acting on the plunger as it moves against the chamber;
determine a change in force per unit volume of the fluid at a first time during infusion;
determine the change in force per unit volume satisfies a threshold at the first time;
determine a difference between a first average force acting on the plunger prior to the first time and a second average force acting on the plunger after a delay time from the first time;
determine the difference satisfies a force differential; and
detect a presence of air in the chamber based on the determination of the difference satisfying the force differential and the determination of the change in force satisfying the threshold.
6. The system of claim 5 , wherein the determination of the change in force per unit volume satisfying the threshold further comprises determining the change in force per unit volume crosses the threshold more than once in a time period after the first time, wherein the time period is less than or equal to the delay time.
7. The system of claim 5 , wherein the change in force per unit volume comprises a change in derivative of force with respect to per unit volume.
8. The system of claim 5 , wherein the delay time is measured with respect to volume of fluid delivered.
9. A method for detecting air in a chamber of an infusion system, the infusion system comprising a pump and a plunger moveably disposed against the chamber, the chamber configured to hold fluid, the method comprising:
receiving a measurement of force acting on the plunger as it moves against the chamber;
determining a change in force per unit volume of the fluid at a first time during infusion;
determining the change in force per unit volume satisfies a threshold at the first time;
determining a difference between a first average force acting on the plunger prior to the first time and a second average force acting on the plunger after a delay time from the first time;
determining the difference satisfies a force differential; and
detecting a presence of air in the chamber based on the determination of the difference satisfying the force differential and the determination of the change in force satisfying the threshold.
10. The method of claim 9 , wherein the determination of the change in force per unit volume satisfying the threshold further comprises determining the change in force per unit volume crosses the threshold more than once in a time period after the first time, wherein the time period is less than or equal to the delay time.
11. The method of claim 9 , wherein the change in force per unit volume comprises a change in derivative of force with respect to per unit volume.
12. The method of claim 9 , wherein the delay time is measured with respect to volume of fluid delivered.
13. The method of claim 9 , further comprising determining a force profile of the plunger and detecting the presence of air based on a change in a shape of the force profile.
14. The method of claim 13 , further comprising classifying the force profile based on a linear discriminate analysis.
15. The method of claim 13 , further comprising normalizing the determined force profile.
16. The method of claim 13 , wherein the force profile comprises a vector corresponding to varying number of positions of the plunger.