Autophage activating resveratrol topical composition for skin improvement and treatment
An autophage activating resveratrol topical composition includes a ceramide or a pseudoceramide, a fatty acid, a phytosterol, and a resveratrol. The ceramide or pseudoceramide, the fatty acid, the phytosterol, and the resveratrol form a multi-layered encapsulation system. A method of inducing autophagy in skin includes applying the autophage activating resveratrol topical composition to a skin, and inducing autophagy in the skin to improve skin barrier function and skin self-purification function.
1. An autophage activating resveratrol topical composition comprising:
0.5-1.0 wt % of a pseudoceramide,
1.0-7.0 wt % of a fatty acid,
0.01-1.0 wt % of a phytosterol, and
0.01-1.0 wt % of a resveratrol,
wherein the ceramide or pseudoceramide, the fatty acid, the phytosterol, and the resveratrol form a multi-layered encapsulation system, and
wherein the pseudoceramide is ceramide 9S, ceramide 5P, or ceramide IIIB.
2. The autophage activating resveratrol topical composition of claim 1 , wherein the fatty acid is a saturated or unsaturated carboxylic acid with a long aliphatic chain.
3. The autophage activating resveratrol topical composition of claim 1 , wherein the phytosterol is selected from the group consisting of β-sitosterol, campesterol, cholesterol, stigmasterol, stigmastanol, campestanol, brassicasterol, ergosterol, lupeol, and cycloartenol.
4. The autophage activating resveratrol topical composition of claim 1 , wherein the resveratrol is represented by the following structure:
5. The autophage activating resveratrol topical composition of claim 1 , wherein the pseudoceramide is in an amount of less than 20% of a total weight of the resveratrol topical composition.
6. The autophage activating resveratrol topical composition of claim 1 , wherein the fatty acid is in an amount of less than 70% of the total weight of the resveratrol topical composition.
7. The autophage activating resveratrol topical composition of claim 1 , wherein a weight ratio of the phytosterol and the resveratrol is between 1:9 to 9:1.
8. The autophage activating resveratrol topical composition of claim 7 , wherein the weight ratio of the phytosterol and the resveratrol is 1:1.
9. The autophage activating resveratrol topical composition of claim 1 further comprising:
emulsifier oils and cosmetic ingredients.
10. A method of inducing autophagy in skin comprising:
applying the autophage activating resveratrol topical composition of claim 1 to a skin, and
inducing autophagy in the skin to improve skin barrier function and skin self-purification function.
11. The method of claim 10 , wherein the skin is a sensitive skin or atopic dermatitis skin.