IP Library Granted Patent US 10,874,339
Granted Patent B2
US 10,874,339 · App. 16/009,912 · Granted Dec 29, 2020

System and method for measuring an amount of blood and/or clotting in a pocket surrounding an implantable medical device

Inventors: Abhi Chavan (Germantown, MD); James Masciotti (Germantown, MD)
Assignee: Senseonics, Incorporated
A61B5/1495A61B5/02042A61B5/1459A61B5/6861A61B5/1451A61B5/14532A61B5/14556A61B2560/0276A61B2562/0238
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Quick Facts
Patent No.
US 10,874,339
App. No.
16/009,912
Granted
Dec 29, 2020
Kind
B2
Abstract

A system and method for measuring an amount of blood and/or clotting in a pocket around an implantable device. The system may include a first light source configured to emit light over a first wavelength range. The system may include a first photodetector configured to output a first signal indicative of an amount of the first light received by the first photodetector. The system may include the implantable device and an external device. The implantable device may include one of the first light source and the first photodetector, and the external device may include the other of the first light source and the first photodetector. In some embodiments, the external device may include a controller configured to calculate the amount of blood/or clotting in the pocket around the implantable device using at least a measurement of the first signal.

Claims (40)

1. A system comprising:

a first light source configured to emit light over a first wavelength range;

a first photodetector configured to output a first signal indicative of an amount of the first light received by the first photodetector;

an implantable device comprising one of the first light source and the first photodetector; and

an external device comprising:

the other of the first light source and the first photodetector; and

a controller configured to calculate an amount of blood in a pocket around the implantable device using at least a measurement of the first signal.

2. The system of claim 1 , further comprising a second light source configured to emit light over a second wavelength range, which is different than the first wavelength range;

wherein one of the implantable device and the external device comprises the second light source.

3. The system of claim 2 , wherein the first photodetector is a common photodetector configured to output the first signal indicative of the amount of the first light received by the common photodetector and to output a second signal indicative of an amount of the second light received by the common photodetector.

4. The system of claim 3 , wherein the controller is configured to calculate the amount of blood in the pocket around the implantable device using at least the measurement of the first signal and a measurement of the second signal.

5. The system of claim 2 , further comprising a second photodetector configured to output a second signal indicative of an amount of the second light received by the second photodetector, wherein the first and second photodetectors are different photodetectors.

6. The system of claim 5 , wherein one of the implantable device and the external device comprises the first and second light sources, and the other of the implantable device and the external device comprises the first and second photodetectors.

7. The system of claim 5 , wherein one of the implantable device and the external device comprises the first light source and the second photodetector, and the other of the implantable device and the external device comprises the second light source and the first photodetector.

8. The system of claim 2 , wherein the first wavelength ranges includes red light, and the second wavelength range includes infrared light.

9. The system of claim 2 , wherein the controller is configured to cause the first and second light sources to emit the first light and second light simultaneously.

10. The system of claim 2 , wherein the controller is configured to cause the first light source to emit the first light during a first time period and to cause the second light source to emit the second light during a second time period, and the first and second time periods are different time periods.

11. The system of claim 1 , wherein the implantable device further comprises:

an excitation light source configured to emit excitation light over an excitation wavelength range;

an analyte indicator configured to receive the excitation light and emit emission light over an emission light wavelength range, wherein the amount of emission light varies in accordance with an amount or concentration of an analyte in a medium within a living animal; and

an analyte photodetector configured to output an analyte signal indicative of an amount of the emission light received by the analyte photodetector.

12. The system of claim 11 , wherein the controller is configured to calculate an analyte level based on at least a measurement of analyte signal and one or more of a measurement of the first signal and a measurement of the second signal.

13. The system of claim 12 , wherein the controller is further configured to compensate for the calculated amount of blood in the pocket when calculating the analyte level.

14. The system of claim 11 , wherein the emission wavelength range includes fluorescent light, the first wavelength range includes red light, and the second wavelength range includes infrared light.

15. A method comprising:

using a first light source to emit light over a first wavelength range;

using a first photodetector to output a first signal indicative of an amount of the first light received by the first photodetector; and

using a controller of an external device to calculate an amount of blood in a pocket around the implantable device using at least a measurement of the first signal;

wherein an implantable device comprises one of the first light source and the first photodetector, and the external device comprises the other of the first light source and the first photodetector.

16. The method of claim 15 , further comprising using a second light source to emit light over a second wavelength range, which is different than the first wavelength range;

wherein one of the implantable device and the external device comprises the second light source.

17. The method of claim 16 , using the first photodetector to output the first signal indicative of the amount of the first light received by the first photodetector and to output a second signal indicative of an amount of the second light received by the first photodetector.

18. The method of claim 17 , wherein the controller calculates the amount of blood in the pocket around the implantable device using at least the measurement of the first signal and a measurement of the second signal.

19. The method of claim 16 , further comprising using a second photodetector to output a second signal indicative of an amount of the second light received by the second photodetector, wherein the first and second photodetectors are different photodetectors.

20. The method of claim 15 , further comprising:

using an excitation light source of the implantable device to emit excitation light over an excitation wavelength range;

using an analyte indicator of the implantable device to receive the excitation light and emit emission light over an emission light wavelength range, wherein the amount of emission light varies in accordance with an amount or concentration of an analyte in a medium within a living animal; and

using an analyte photodetector of the implantable device to output an analyte signal indicative of an amount of the emission light received by the analyte photodetector.

21. The method of claim 20 , further comprising using the controller of the external device to calculate an analyte level based on at least a measurement of analyte signal and one or more of a measurement of the first signal and a measurement of the second signal.

22. The method of claim 21 , wherein calculating the analyte level comprises compensating for the calculated amount of blood in the pocket.

Assignments (10)
SECURITY INTEREST Recorded Sep 11, 2023
From: SENSEONICS, INCORPORATED
To: HERCULES CAPITAL, INC.
Reel/Frame 064866/0963 →
RELEASE OF SECURITY INTEREST Recorded Sep 7, 2023
From: WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT
To: SENSEONICS, INCORPORATED; SENSEONICS HOLDINGS, INC.
Reel/Frame 064834/0962 →
RELEASE OF SECURITY INTEREST Recorded Apr 14, 2023
From: ALTER DOMUS (US) LLC, AS COLLATERAL AGENT
To: SENSEONICS HOLDINGS, INC.; SENSEONICS, INCORPORATED
Reel/Frame 063338/0890 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 5, 2020
From: CHAVAN, ABHI; MASCIOTTI, JAMES
To: SENSEONICS, INCORPORATED
Reel/Frame 054286/0333 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Aug 14, 2020
From: SENSEONICS, INCORPORATED
To: ALTER DOMUS (US) LLC, AS COLLATERAL AGENT
Reel/Frame 053496/0292 →
RELEASE OF SECURITY INTEREST IN PATENTS AND TRADEMARKS Recorded Aug 14, 2020
From: WILMINGTON SAVINGS FUND SOCIETY, FSB, COLLATERAL AGENT
To: SENSEONICS, INCORPORATED; SENSEONICS HOLDINGS, INC.
Reel/Frame 053498/0275 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT - FIRST LIEN Recorded Apr 24, 2020
From: SENSEONICS, INCORPORATED; SENSEONICS HOLDINGS, INC.
To: WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT
Reel/Frame 052492/0109 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT -SECOND LIEN Recorded Apr 24, 2020
From: SENSEONICS, INCORPORATED; SENSEONICS HOLDINGS, INC.
To: WILMINGTON SAVINGS FUND SOCIETY, FSB, AS COLLATERAL AGENT
Reel/Frame 052490/0160 →
RELEASE OF SECURITY INTEREST Recorded Mar 23, 2020
From: SOLAR CAPITAL LTD., AS AGENT
To: SENSEONICS, INCORPORATED
Reel/Frame 052207/0242 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Aug 1, 2019
From: SENSEONICS, INCORPORATED
To: SOLAR CAPITAL LTD., AS AGENT
Reel/Frame 049926/0827 →
Cited By (1)
US 12,558,289