Prosthetic heart valve devices and associated systems and methods
Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an expandable support having an outer surface and configured for placement between leaflets of the native valve. The device can also include a plurality of asymmetrically arranged arms coupled to the expandable support and configured to receive the leaflets of the native valve between the arms and the outer surface. In some embodiments, the arms can include tip portions for engaging a subannular surface of the native valve.
1. A prosthetic heart valve device for treating a native mitral valve having a native annulus and native leaflets, comprising:
a valve member configured to allow blood flow in a downstream direction toward a ventricle and at least partially blocking blood flow in an upstream direction toward an atrium;
a support carrying the valve member;
an anchoring portion coupled to and at least partially extending around the support, the anchoring member having a downstream end and an upstream end, wherein the anchoring portion extends outwardly from the downstream end in an upstream direction such that the anchoring portion has a greater diameter at the upstream end than at the downstream end, wherein the anchoring portion is configured to exert force against an inner surface of the native leaflets when the prosthetic heart valve device is in an expanded configuration at the native annulus; and
a skirt on the anchoring portion and flaring outwardly in the upstream direction such that an upstream region of the skirt is spaced outwardly from the support, wherein the skirt extends around the entire circumference of the anchoring portion.
2. The prosthetic heart valve device of claim 1 wherein the anchoring portion comprises a plurality of elongated members.
3. The prosthetic heart valve device claim 1 wherein the valve member comprises a tri-leaflet assembly.
4. The prosthetic heart valve device of claim 1 wherein the anchoring portion is biased outwardly from the support.
5. The prosthetic heart valve device of claim 1 wherein the skirt extends along on an outer side of anchoring portion.
6. The prosthetic heart valve device of claim 1 wherein the support comprises interconnected struts.
7. The prosthetic heart valve device of claim 1 wherein, when expanded at the native annulus, the anchoring portion has a kidney-shape to conform to the native annulus.
8. A prosthetic heart valve device for treating a native mitral valve having a native annulus and native leaflets, comprising:
an expandable support;
a prosthetic valve carried by the expandable support;
an anchoring portion coupled to and surrounding at least a portion of the expandable support, wherein, when the prosthetic heart valve device is in an expanded configuration
the anchoring portion extends outwardly from a ventricular region of the prosthetic heart valve device toward an atrial region of the prosthetic heart valve device such that an atrial end of the anchoring portion is spaced radially outwardly from the support, and
the anchoring portion is configured to remain inward of the native leaflets and exert force against an inner surface of the native leaflets; and
a skirt coupled to and extending around the entire circumference of the anchoring portion.
9. The prosthetic hear valve device of claim 8 wherein the anchoring portion comprises a plurality of elongated members biased outwardly in the expanded configuration to exert force against the inner surface of the native leaflets.
10. The prosthetic heart valve device of claim 8 wherein, when expanded at the native annulus, the anchoring portion is arranged in an oval shape to conform to the native annulus.
11. A prosthetic heart valve device for treating a native mitral valve having a native annulus and native leaflets, the prosthetic heart valve device comprising:
an expandable support;
a prosthetic valve attached to the expandable support, wherein the prosthetic valve is configured to allow blood flow in a downstream direction toward a left ventricle and at least partially prevent blood flow in an upstream direction toward a left atrium;
a plurality of elongated members coupled to and surrounding the expandable support, wherein
when the prosthetic heart valve device is in an expanded configuration, the elongated members extend from a downstream portion of the prosthetic heart valve device toward an upstream portion of the prosthetic heart valve device such that the elongated members are spaced apart from the support at the upstream portion,
the elongated members are configured to press against an inner surface of the native leaflets; and
a covering at least partially covering the elongated members such that an upstream end of the covering is spaced outwardly from the support, wherein the skirt extends around the entire circumference of the support.
12. The prosthetic heart valve device of claim 11 wherein the elongated members extend outwardly from the downstream portion in an upstream direction.
13. The prosthetic heart valve device of claim 11 wherein the covering extends along an outer side of elongated members.
14. The prosthetic heart valve device of claim 11 wherein the support comprises interconnected struts.
15. The prosthetic heart valve device of claim 11 wherein, when expanded at the native annulus, the elongated members are configured to conform to an oval or kidney-shape of the native annulus.