IP Library › Granted Patent US 10,512,622
Granted Patent B2
US 10,512,622 · App. 16/032,380 · Granted Dec 24, 2019

Treatment of intrahepatic cholestatic diseases

Inventors: Pol Boudes (Fremont, CA); Charles A. McWherter (Oakland, CA)
Assignee: CymaBay Therapeutics, Inc.
A61K31/192A61K9/0053A61K9/4858A61P1/16
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Quick Facts
Patent No.
US 10,512,622
App. No.
16/032,380
Granted
Dec 24, 2019
Kind
B2
Abstract

Treatment of intrahepatic cholestatic diseases by therapy with seladelpar or a salt thereof.

Claims (10)

1. A method of treating primary biliary cholangitis by administering a therapeutically effective amount of a compound that is seladelpar or a salt thereof, where the amount of the compound is between 0.5 mg/day and 2 mg/day when the amount of the compound is calculated as seladelpar.

2. The method of claim 1 where the compound is administered orally.

3. The method of claim 1 where the amount of the compound is 0.5 mg/day, 1 mg/day, or 2 mg/day.

4. The method of claim 3 where the amount of the compound is 0.5 mg/day.

5. The method of claim 3 where the amount of the compound is 1 mg/day.

6. The method of claim 3 where the amount of the compound is 2 mg/day.

7. The method of claim 1 where the compound is administered once/day.

8. The method of claim 1 where the compound is administered between once/week and every other day.

9. The method of claim 1 where the compound is a seladelpar L-lysine salt.

10. The method of claim 9 where the compound is seladelpar L-lysine dihydrate salt.

Assignments (2)
RELEASE OF SECURITY INTEREST Recorded Oct 3, 2024
From: ABW CYCLOPS SPV LP
To: CYMABAY THERAPEUTICS, INC.
Reel/Frame 069833/0155 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 31, 2018
From: BOUDES, POL; MCWHERTER, CHARLES A
To: CYMABAY THERAPEUTICS, INC.
Reel/Frame 046517/0686 →