Nutritional compositions comprising hydrolyzed protein and a modified fat system and uses thereof
Disclosed embodiments provide nutritional compositions and methods of enhancing maturation of an infant's brain. The methods include the step of administering to the infant a nutritional composition comprising a protein with a degree of hydrolysis of 10% to 75% in combination with at least one of a monoglyceride, a free fatty acid, a salt of a free fatty acid, a phospholipid, and cholesterol.
1. A method of inhibiting neuronal cell death in an infant in need thereof, the method comprising administering to the infant a nutritional composition consisting essentially of a casein protein with a degree of hydrolysis of 10% to 75% and a mixture of a monoglycerol palmitate, soy lecithin, cholesterol, and at least one of a free fatty acid from soy and a salt of a free fatty acid from soy, and wherein after administration the infant's neuronal cell death is reduced.
2. The method of claim 1 , wherein the infant in need thereof is a preterm infant.
3. The method of claim 1 , wherein the nutritional composition is a human milk fortifier.
4. The method of claim 1 , wherein the nutritional composition is a powdered human milk fortifier.
5. The method of claim 1 , wherein the nutritional composition is an infant formula.
6. The method of claim 5 , wherein the nutritional composition is a preterm infant formula.
7. The method of claim 1 , wherein the nutritional composition further comprises a carbohydrate.
8. A method of treating neuronal tissue inflammation in an infant in need thereof, the method comprising administering to the infant a nutritional composition consisting essentially of a casein protein with a degree of hydrolysis of 10% to 75% and a mixture of a monoglycerol palmitate, soy lecithin, cholesterol, and at least one of a free fatty acid from soy and a salt of a free fatty acid from soy, and wherein after administration the infant's neuronal tissue inflammation is reduced.
9. The method of claim 8 , wherein the nutritional composition is a human milk fortifier.
10. The method of claim 9 , wherein the nutritional composition is a powdered human milk fortifier.
11. The method of claim 8 , wherein the nutritional composition is an infant formula.
12. The method of claim 11 , wherein the nutritional composition is a preterm infant formula.
13. A method of reducing neuronal tissue inflammation in an infant in need thereof, the method comprising administering to the infant a nutritional composition consisting essentially of a casein protein with a degree of hydrolysis of 10% to 75% and a mixture of a monoglycerol palmitate, soy lecithin, cholesterol, and at least one of a free fatty acid from soy and a salt of a free fatty acid from soy.