IP Library Granted Patent US 10,918,678
Granted Patent B2
US 10,918,678 · App. 16/072,319 · Granted Feb 16, 2021

Patent

Inventors: Philippe Langella (Velizy-Villacoublay, FR); Rebeca Martin Rosique (Jouy en Josas, FR); Luis Bermudez Humaran (Jouy en Josas, FR); Florian Chain (Versailles, FR); Harry Sokol (Paris, FR)
Assignees: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA); SORBONNE UNIVERSITE; ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
A61K35/74A23L33/135A61K35/741A61P1/00C12R1/01A23V2002/00A23V2200/32A23V2200/3204
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Quick Facts
Patent No.
US 10,918,678
App. No.
16/072,319
Granted
Feb 16, 2021
Kind
B2
Abstract

The invention relates to a bacterial strain of species Faecalibacterium prausnitzii deposited at the CNCM under access number CNCM I-4573, for use in the treatment and/or prevention of an inflammatory gastrointestinal illness in an individual.

Claims (15)

1. Method for the treatment of an inflammatory gastrointestinal disease in an individual comprising administering to the said individual a bacterial strain of the species Faecalibacterium prausnitzii deposited with the CNCM under accession number CNCM 1-4573.

2. The method as claimed in claim 1 , characterized in that the individual is a mammal.

3. The method as claimed in claim 1 , characterized in that the individual is a human being.

4. The method as claimed in claim 1 , characterized in that the inflammatory gastrointestinal disease is an inflammatory bowel disease.

5. The method as claimed in claim 1 , characterized in that the inflammatory gastrointestinal disease is a colonic inflammatory bowel disease.

6. The method as claimed in claim 5 , characterized in that the colonic inflammatory bowel disease is chosen from the group consisting of Crohn's disease, ulcerative colitis and pouchitis.

7. The method as claimed in claim 5 , characterized in that the colonic inflammatory bowel disease is chosen from the group consisting of Crohn's disease and ulcerative colitis.

8. The method as claimed in claim 1 , characterized in that the bacterial strain is included in a composition comprising a physiologically acceptable medium.

9. The method as claimed in claim 1 , characterized in that the bacterial strain is included in an oral composition.

10. The method as claimed in claim 1 , characterized in that the bacterial strain is included in a food supplement.

11. The method as claimed in claim 8 , characterized in that the composition is suitable for the administration of a daily dose representing from 10 7 to 10 11 colony-forming units (cfu) as a medicament.

12. The method as claimed in claim 8 , characterized in that the composition is for oral administration and is chosen from the group consisting of a food product, a beverage, a pharmaceutical product, a nutraceutical, a food additive, a food supplement and a milk product.

13. The method as claimed in claim 12 , characterized in that the composition is for oral administration and is a food supplement.

14. The method as claimed in claim 9 , characterized in that the composition is suitable for the administration of a daily dose representing from 10 7 to 10 11 colony-forming units (cfu) as a medicament.

15. The method as claimed in claim 10 , characterized in that the composition is suitable for the administration of a daily dose representing from 10 7 to 10 11 colony-forming units (cfu) as a medicament.

Assignments (2)
CHANGE OF NAME Recorded Jan 12, 2021
From: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA)
To: INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
Reel/Frame 054972/0888 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 31, 2019
From: LANGELLA, PHILIPPE; MARTIN ROSIQUE, REBECA; BERMUDEZ HUMARAN, LUIS; CHAIN, FLORIAN; SOKOL, HARRY
To: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA); SORBONNE UNIVERSITE; ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS
Reel/Frame 048207/0526 →