IP Library Granted Patent US 12,239,136
Granted Patent B2
US 12,239,136 · App. 16/076,424 · Granted Mar 4, 2025

Mixtures and compositions comprising

Inventors: Isabella Siepe (Limburgerhof, DE); Burghard Liebmann (Limburgerhof, DE); Thorsten Jabs (Ludwigshafen, DE); Annette Schuster (Limburgerhof, DE)
Assignee: BASF SE
A01N63/25A01H3/00A01N37/46C12N1/20C12R2001/01Y02A50/30
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Quick Facts
Patent No.
US 12,239,136
App. No.
16/076,424
Granted
Mar 4, 2025
Kind
B2
Abstract

The present invention relates to novel mixtures comprising, as active components, at least one isolated bacterial strain, which is a member of the genus Paenibacillus , or a cell-free extract thereof or at least one metabolite thereof, and at least one chemical pesticide. The present invention also relates to compositions comprising at least one of such bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and at least one chemical pesticide. The present invention also relates to a method of controlling or suppressing plant pathogens or preventing plant pathogen infections by applying such composition. The present invention also relates to mixtures of fusaricidins which are pesticidal metabolites produced by the abovementioned strains, and chemical pesticides.

Claims (41)

1. A mixture, comprising as active components 1) at least one Paenibacillus strain selected from the group consisting of:

a) Paenibacillus polymyxa strain Lu16774 deposited with DSMZ under Accession No. DSM 26969;

b) Paenibacillus polymyxa strain Lu17007 deposited with DSMZ under Accession No. DSM 26970;

c) Paenibacillus epiphyticus strain Lu17015 deposited with DSMZ under Accession No. DSM 26971; and

d) a mutant of strain a) or b) which comprises a nucleic acid having a nucleotide sequence having

100% nucleotide sequence identity to the DNA sequences SEQ ID NO:4 or SEQ ID NO:9; or

100% nucleotide sequence identity to the DNA sequences SEQ ID NO:5 or SEQ ID NO:10; or

100% nucleotide sequence identity to the DNA sequences SEQ ID NO:6 or SEQ ID NO:11; or

100% nucleotide sequence identity to the DNA sequences SEQ ID NO:7 or SEQ ID NO:12; or

100%-nucleotide sequence identity to the DNA sequences SEQ ID NO: 8 or SEQ ID NO:13; and

e) a mutant of strain c) which comprises a nucleic acid having a nucleotide sequence having

100%-nucleotide sequence identity to the DNA sequence SEQ ID NO: 14; and

100%-nucleotide sequence identity to the DNA sequence SEQ ID NO: 15; and

100%-nucleotide sequence identity to the DNA sequence SEQ ID NO: 16; and

100%-nucleotide sequence identity to the DNA sequence SEQ ID NO: 17; and

100%-nucleotide sequence identity to the DNA sequence SEQ ID NO: 18;

wherein said at least one Paenibacillus strain produces a compound 1A and/or a compound 1B in a growth medium comprising at least one source of carbon and one source of nitrogen:

and

2) at least one pesticide selected from the group consisting of: Pyraclostrobin, Azoxystrobin, Dimoxystrobin, Orysastrobin, Picoxystrobin, Trifloxystrobin, Benzovindiflupyr, Fluopyram, Fluxapyroxad, Bixafen, Penflufen, Penthiopyrad, Sedaxane, Silthiofam, Difenoconazole, Metconazole, Prothioconazole, Triticonazole, Mefentrifluconazole, Epoxiconazole, Ipconazole, Tebuconazole, Triadimenol, Prochloraz, Metalaxyl, metalaxyl-M, Thiabendazole, Thiophanate methyl, Ethaboxam, Pyrimethanil, Fludioxonil, Dimethomorph, Thiram, and Picarbutrazox,

wherein the mixture comprises component 1) and component 2) in a synergistically effective amount.

2. The mixture according to claim 1 , wherein said at least one Paenibacillus strain has antifungal activity against at least two plant pathogens of the plant pathogen selected from the group consisting of Alternaria spp., Botrytis cinerea, Phytophthora infestans and Sclerotinia sclerotiorum.

3. A composition comprising the mixture as defined in claim 1 and an auxiliary.

4. The composition of claim 3 , comprising a further pesticide selected from the group consisting of:

pyraclostrobin, azoxystrobin, picoxystrobin, trifloxystrobin, dimoxystrobin, enestroburin, fenaminstrobin, fluoxastrobin, kresoxim-methyl, mandestrobin, metominostrobin, orysastrobin, pyrametostrobin, pyraoxystrobin,

fluxapyroxad, boscalid, benzovindiflupyr, penflufen, penthiopyrad, sedaxane, fluopyram, bixafen, isopyrazam,

carboxin, benodanil, fenfuram, flutolanil, furametpyr, mepronil, oxycarboxin, thifluzamide,

silthiofam,

ipconazole, difenoconazole, prothioconazole, prochloraz, triticonazole, flutriafol, cyproconazole, diniconazole, diniconazole-M, fluquinconazole, flusilazole, hexaconazole, imazalil, imibenconazole, metconazole, myclobutanil, simeconazole, tebuconazole, triadimenol, uniconazole, thiabendazole,

oxathiapiprolin, valifenalate, metalaxyl, metalaxyl-M, ethaboxam, dimethomorph, zoxamide, flumorph, mandipropamid, pyrimorph, benthiavalicarb, iprovalicarb,

fludioxonil,

thiophanate-methyl, carbendazim,

thiram, ziram,

fipronil, ethiprole, vaniliprole, pyrafluprole, pyriprole, 5-amino-1-(2,6-dichloro-4-methyl-phenyl)-4-sulfinamoyl-1H-pyrazole-3-carbothioic acid amide,

chlorantraniliprole, flubendiamide,

cyantraniliprole,

tefluthrin, bifenthrin, cypermethrin, alpha-cypermethrin, cyfluthrin, beta-cyfluthrin, lambda-cyhalothrin, deltamethrin, esfenvalerate, etofenprox, fenvalerate, flucythrinate, permethrin,

clothianidin, imidacloprid, thiamethoxam, dinotefuran, acetamiprid, flupyradifurone, thiacloprid, triflumezopyrim, nitenpyram,

sulfoxaflor, acephate, chlorpyrifos, thiodicarb, abamectin, spinosad, and

tioxazafen,

wherein the further pesticide is different from the pesticide of component 2).

5. A plant propagation material having a coating comprising the composition as defined in claim 3 .

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 15, 2019
From: SIEPE, ISABELLA; LIEBMANN, BURGHARD; JABS, THORSTEN; SCHUSTER, ANNETTE
To: BASF SE
Reel/Frame 048009/0091 →
Priority Claims (1)
EP 16154807 · Feb 9, 2016 · regional
Continuity (1)
Related Publication 20190110480A1 · Apr 18, 2019
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