Occlusion device
Provided herein is an occlusion device comprising: (a) a substantially solid marker band having an inner and outer diameter, a proximal end, and a distal end; and (b) a resilient mesh body attached within the marker band, wherein the body is a length y, and wherein the body comprises a bolus of additional resilient mesh material of a length x, wherein y is greater than x, and wherein the body extends distally from the marker band having a first delivery shape and a second expandable deployed shape. Also provided herein is a kit comprising the occlusion device disclosed herein and a means for delivery thereof. Methods of manufacture and use of the occlusion device disclosed herein are also disclosed.
1. An occlusion device comprising: (a) a substantially solid marker band having an inner and outer diameter, a proximal end, and a distal end; and (b) a resilient mesh body attached within the marker band, wherein the body has a length y, and wherein the body further comprises a bolus of additional resilient mesh material of a length x, wherein y is greater than x, wherein the body is a dual layer of resilient mesh folded over onto itself, has folded over ends of the resilient mesh, all the folded over ends of the dual layer of mesh are attached within the marker, and wherein the body extends distally from the marker band having a first delivery shape and a second expandable deployed inverted mushroom shape.
2. The occlusion device of claim 1 , wherein the body comprises a circumferentially folded dual layer of mesh.
3. The occlusion device of claim 1 , wherein the body has an open mesh density for enhanced tissue integration and/or stabilization of the occlusion device.
4. The occlusion device of claim 1 , wherein resilient mesh body and the bolus of additional resilient mesh material are dissimilar metals.
5. The occlusion device of claim 1 , wherein the resilient mesh body is constructed from a super elastic material.
6. The occlusion device of claim 5 , wherein the resilient mesh body is constructed from nitinol.
7. The occlusion device of claim 5 , wherein the resilient mesh body is constructed from DFT platinum core nitinol.
8. The occlusion device of claim 1 , wherein the bolus of additional resilient mesh is constructed from a super elastic material.
9. The occlusion device of claim 8 , wherein the bolus of additional resilient mesh is constructed from nitinol.
10. The occlusion device of claim 8 , wherein the bolus of additional resilient mesh is constructed from DFT platinum core nitinol.
11. The occlusion device of claim 1 , wherein the marker band comprises a rigid member.
12. The occlusion device of claim 11 , wherein the rigid member is a ring, or a collar.
13. The occlusion device of claim 1 , wherein the marker band is reinforced.
14. The occlusion device of claim 1 , which is a Left Atrial Appendage (LAA) occlusion device.
15. A method for treating or ameliorating Left Atrial Appendage (LAA) in a patient, the method comprising:
i.) delivering to an LAA an occlusion device, wherein the device comprises (a) a substantially solid marker band having an inner and outer diameter, a proximal end, and a distal end; and (b) a resilient mesh body attached within the marker band, wherein the body is a length y, and wherein the body further comprises a bolus of additional resilient mesh material of a length x, wherein y is greater than x,
ii.) wherein the body is a dual layer of resilient mesh folded over onto itself, all the folded over ends of the dual layer of mesh are attached within the marker, and wherein the body extends distally from the marker band having a first delivery shape and a second expandable deployed inverted mushroom shape; and
ii.) deploying the occlusion device in the LAA, thereby treating or ameliorating LAA in the patient.
16. The method of claim 15 , which comprises deploying the device through the left atrial space adjacent to the LAA using an electrolytic wire.
17. The method of claim 15 , which comprises deploying the device with a catheter.