IP Library Granted Patent US 11,399,759
Granted Patent B2
US 11,399,759 · App. 16/097,959 · Granted Aug 2, 2022

Cardiac mapping system with efficiency algorithm

Inventors: Daniel Welsh (Encinitas, CA); Derrick Ren-yu Chou (San Diego, CA); Haizhe Zhang (San Diego, CA); Leo Mariappan (Oceanside, CA); Min Zhu (San Marcos, CA); Steven Anthony Yon (San Diego, CA); Xinwei Shi (San Diego, CA); Graydon Ernest Beatty (Carlsbad, CA); Nathan Angel (Oceanside, CA); Weiyi Tang (San Diego, CA); Christoph Scharf (Horgen, CH); Christopher J. Flaherty (Auburndale, FL); Ahmad Falahatpisheh (San Marcos, CA)
Assignee: ACUTUS MEDICAL, INC.
A61B5/25A61B5/05A61B5/107A61B5/283A61B5/291A61B5/296A61B5/30A61B5/318A61B5/339A61B8/0883A61B8/12A61B8/4416A61B8/4477A61B18/14A61B34/20A61B5/361A61B5/6858A61B2017/00106A61B2018/00267A61B2018/00351A61B2018/00839A61B2034/105
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Quick Facts
Patent No.
US 11,399,759
App. No.
16/097,959
Granted
Aug 2, 2022
Kind
B2
Abstract

A cardiac information dynamic display system comprises: one or more electrodes configured to record sets of electric potential data representing cardiac activity at a plurality of time intervals; and a cardiac information console, comprising: a signal processor configured to: calculate sets of cardiac activity data at the plurality of time intervals using the recorded sets of electric potential data, wherein the cardiac activity data is associated with surface locations of one or more cardiac chambers; and a user interface module configured to display a series of images, each image comprising: a graphical representation of the cardiac activity. Methods of providing cardiac activity data are also provided.

Claims (23)

1. A cardiac information dynamic display system, comprising:

one or more electrodes configured to record sets of electric potential data representing cardiac activity at a plurality of time intervals; and a cardiac information console, comprising:

a signal processor configured to: perform an inverse solution using truncated Tikhonov regularization to calculate sets of cardiac activity data at the plurality of time intervals using the recorded sets of electric potential data, wherein the cardiac activity data includes charge density data associated with surface locations of one or more cardiac chambers; and a user interface module configured to generate one or more displays comprising a series of images, each image comprising: a graphical representation of at least some of the charge density data associated with surface locations of the one or more cardiac chambers, wherein the signal processor is configured to execute a scaling algorithm to:

perform a pre-scaling portion before the inverse solution that uses a weighted minimum norm estimate to compensate for distance effects between the electrodes and the surface locations of the one or more cardiac chambers to improve the Tikhonov regularization in computing the sets of cardiac activity data, and perform a post-scaling portion on the outputs of the inverse solution that uses a uniform source distribution to compute post-scaling values, wherein the post-scaling values are used to adjust the sets of cardiac activity data from the weighted minimum norm estimate.

2. The system of claim 1 , wherein the signal processor performs a truncated SVD for computing a matrix inversion to solve the Tikhonov regularization, which includes a plurality of full SVD computations and transpositions using less than all singular values of bio-potentials measured in a time interval.

3. The system of claim 1 , wherein the signal processor performs a truncated SVD for computing a matrix inversion to solve the Tikhonov regularization directly from less than all singular values of bio-potentials measured in a time interval.

4. The system of claim 1 , wherein the signal processor is configured to perform a regularized inverse solution to the Tikhonov regularization.

5. The system of claim 1 , wherein the one or more electrodes comprise an electrode array.

6. The system of claim 5 , wherein the electrode array records sets of electric potential data from multiple recording positions of the electrode array within the one or more cardiac chambers.

7. The system of claim 6 , wherein the signal processor calculates the sets of cardiac activity data based on a subset of the multiple recording positions.

8. The system of claim 7 , wherein the subset of recording positions is based on relative change between recording positions of the electrode array within the one or more cardiac chambers.

9. The system of claim 1 , wherein the charge density data is calculated using a forward matrix.

10. The system of claim 1 , wherein the system generates a model of the cardiac anatomy for a patient, and the cardiac information algorithm comprises a forward matrix, wherein the forward matrix is based on the model of the cardiac anatomy.

11. The system of claim 10 , wherein regarding the scaling algorithm, the pre-scaling portion is executable to reduce distance influence on the forward matrix and the post-scaling portion is executable to adjust the output of the inverse solution.

12. The system of claim 10 , wherein the model of the cardiac anatomy is based on at least one image of the one or more cardiac chambers.

13. The system of claim 12 , further comprising at least one ultrasound transducer configured to generate ultrasound data used to generate and/or update the model of the cardiac anatomy.

14. The system of claim 10 , wherein the model of the cardiac anatomy is based on a first set of cardiac activity data and the system is further configured to dynamically update the model of the cardiac anatomy based on a second set of cardiac activity data recorded at a different time interval, and wherein the forward matrix is updated based on the dynamically updated model of the cardiac anatomy.

15. The system of claim 10 , wherein the cardiac information console is configured to apply a median filter to remove noise from the propagation history map.

16. The system of claim 10 , wherein the at least some electrodes mounted on a catheter includes electrodes mounted on a basket array.

17. The system of claim 1 , wherein the system is configured to display maps representing the sets of cardiac electrical activity data.

18. The system of claim 17 , wherein the maps comprise an activation detection map displaying the activation of charge sources on the surface locations of the one or more cardiac chambers.

19. The system of claim 17 , wherein the maps comprise a propagation history map displaying the propagation of charge source activation over the surface locations of the one or more cardiac chambers.

20. The system of claim 1 , wherein the plurality of electrodes includes at least some electrodes mounted on a catheter and configured for insertion into the body.

Assignments (5)
RELEASE OF SECURITY INTEREST Recorded Jun 3, 2026
From: WILMINGTON TRUST, NATIONAL ASSOCIATION
To: ACUTUS MEDICAL, INC.
Reel/Frame 075681/0812 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 14, 2025
From: ACUTUS MEDICAL, INC.
To: ENCHANNEL MEDICAL, LTD.
Reel/Frame 071698/0777 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 13, 2019
From: FALAHATPISHEH, AHMAD
To: ACUTUS MEDICAL, INC.
Reel/Frame 050037/0964 →
SECURITY INTEREST Recorded May 21, 2019
From: ACUTUS MEDICAL, INC.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS ADMINSTRATIVE AGENT
Reel/Frame 049245/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 12, 2018
From: WELSH, DANIEL; CHOU, DERRICK REN-YU; ZHANG, HAIZHE; MARIAPPAN, LEO; ZHU, MIN; YON, STEVEN ANTHONY; SHI, XINWEI; BEATTY, GRAYDON ERNEST; ANGEL, NATHAN; TANG, WEIYI; SCHARF, CHRISTOPH; FLAHERTY, J. CHRISTOPHER
To: ACUTUS MEDICAL, INC.
Reel/Frame 047477/0734 →
Cited By (1)
US 12,685,474