Angular multiplexed optical coherence tomography systems and methods
Angle multiplexed optical coherence tomography systems and methods can be used to evaluate ocular tissue and other anatomical structures or features of a patient. The angle multiplexed optical coherence tomography system includes a light source, an optical assembly for obtaining a plurality of sample beams corresponding to respective anatomical locations of the eye of the patient, where individual sample beams are associated with a respective non-zero angle relative to a reference beam, and a detection mechanism that detects individual unique interference patterns respectively provided by the plurality of sample beams, for simultaneous evaluation of the anatomical locations.
1. An optical coherence tomography system, comprising:
a detector comprising an array of pixels;
a light source configured to supply a sample light beam to an eye and to further supply a reference light beam;
an optical element configured to direct the reference light beam to the array of pixels; and
an optical splitter configured to divide light returning from the eye into a plurality of individual signal beams each having a corresponding different path length from an output of the optical splitter to the optical element and each corresponding to a respective different anatomical location of the eye,
wherein each of the individual signal beams impinges on the optical element at a corresponding different angle with respect to the reference light beam, and
wherein the optical element is configured to direct the plurality of individual signal beams simultaneously to the array of pixels.
2. The optical coherence tomography system of claim 1 , wherein the detector is configured to detect individual unique interference patterns respectively provided by the plurality of individual signal beams and the reference beam, for simultaneous evaluation of the different anatomical locations of the eye.
3. The optical coherence tomography system of claim 2 , wherein unique interference spatial periods of the unique interference patterns are adjustable in response to changes in respective individual signal beam angles relative to the reference beam.
4. The optical coherence tomography system of claim 1 , wherein the optical element comprises one or more collimation lenses that direct combined signal-reference beam pairs toward the detector.
5. The optical coherence tomography system of claim 1 , wherein the system provide an accuracy for range finding on an order of 10 microns.
6. The optical coherence tomography system of claim 1 , further comprising a filter assembly that transmits interference signals at spatial frequencies about a first signal-reference beam pair and suppresses interference signals at spatial frequencies about a second signal-reference beam pair.
7. A method of optical coherence tomography, comprising:
supplying a sample light beam from a light source to an eye, and further supplying a reference light beam from the light source;
an optical element directing the reference light beam to a detector comprising an array of pixels; and
an optical splitter dividing light returning from the eye into a plurality of individual signal beams each having a corresponding different path length from an output of the optical splitter to the optical element, and each corresponding to a respective different anatomical location of the eye,
wherein each of the individual signal beams impinges on the optical element at a corresponding different angle with respect to the reference light beam, and
wherein the optical element directs the plurality of individual signal beams simultaneously to the array of pixels.
8. The method of claim 7 , further comprising detecting, by the detector, individual unique interference patterns respectively provided by the plurality of sample beams.
9. The method of claim 8 , further comprising evaluating the eye based on the detected interference patterns.
10. The method according to claim 9 , further comprising positioning a corneal topography system relative to the eye based on the evaluation, and obtaining a corneal topography measurement of the eye.
11. The method according to claim 10 , wherein the topography measurement is performed without aligning the corneal topography system using corneal topography fiducials.