IP Library Granted Patent US 10,898,220
Granted Patent B2
US 10,898,220 · App. 16/121,104 · Granted Jan 26, 2021

Method of harvesting tissue using sequential sections of a two dimensional array of needles

Inventors: Marvin A. Guiles (Stow, MA); Denis Labombard (Georgetown, MA); Charles Sidoti (Boston, MA); Sameer Sabir (Arlington, MA)
Assignee: Medline Industries, Inc.
A61B17/32053A61B17/3205A61B5/15142A61B5/150396A61B5/150503
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Quick Facts
Patent No.
US 10,898,220
App. No.
16/121,104
Granted
Jan 26, 2021
Kind
B2
Abstract

In one aspect, the present disclosure relates to a method for harvesting biological tissue. In some embodiments, the method includes providing a device having a plurality of segments of hollow tubes, each hollow tube having at least one point at the distal end of the hollow tube, the plurality of segments forming a two dimensional array of hollow tubes, wherein each segment can include a plurality of hollow tubes; positioning the two dimensional array of hollow tubes proximal to an upper surface of a biological tissue; advancing a first segment of the two dimensional array of hollow tubes into the biological tissue to sever portions of the biological tissue from the surrounding tissue; raising the first segment of the two dimensional array of hollow tubes such that the biological tissue remains in each of the hollow tubes of the first segment; advancing a second segment of the two dimensional array of hollow tubes into the biological tissue to sever portions of the biological tissue from the surrounding tissue; and raising the second segment of the two dimensional array of hollow tubes such that the biological tissue remains in each of the hollow tubes of the second segment.

Claims (31)

1. A method for grafting biological tissue, the method comprising:

providing a device having a plurality of segments of hollow tubes, each hollow tube comprising at least one point at a distal end of the hollow tube, the plurality of segments forming a two dimensional array of hollow tubes, wherein each segment comprises a plurality of hollow tubes;

positioning the two dimensional array of hollow tubes proximal to an upper surface of a biological tissue;

detecting, via the device, an applied force of the device to the upper surface of the biological tissue; and

during a harvesting process, generating an alert upon determining the applied force is less than a predetermined force value, the harvesting process comprising:

advancing a first segment of the two dimensional array of hollow tubes into the biological tissue to sever portions of the biological tissue from surrounding tissue;

raising the first segment of the two dimensional array of hollow tubes such that the biological tissue remains in each of the hollow tubes of the first segment;

advancing a second segment of the two dimensional array of hollow tubes into the biological tissue to sever portions of the biological tissue from the surrounding tissue; and

raising the second segment of the two dimensional array of hollow tubes such that the biological tissue remains in each of the hollow tubes of the second segment.

2. The method of claim 1 , wherein the first segment comprises a row of hollow tubes.

3. The method of claim 1 , wherein the first segment comprises a plurality of rows of hollow tubes.

4. The method of claim 1 , wherein the first segment comprises a portion of a row of hollow tubes.

5. The method of claim 1 , wherein the first segment comprises a plurality of portions of rows of hollow tubes.

6. The method of claim 1 , wherein each hollow tube has an inner diameter less than about 1 mm.

7. The method of claim 1 , wherein each hollow tube has an inner diameter less than about 0.8 mm.

8. The method of claim 1 further comprising: providing a plurality of pins, each of the pins located within a central lumen of each of the hollow tubes.

9. The method of claim 8 , further comprising a scattering process comprising:

positioning the two dimensional array of hollow tubes over a wound site;

scattering the biological tissue within each of the hollow tubes of the first segment over the wound; and

scattering the biological tissue within each of the hollow tubes of the second segment over the wound site.

10. The method of claim 9 , wherein the scattering of the biological tissue within each of the hollow tubes of the first segment and the second segment occur at the same time or at different times.

11. The method of claim 9 , wherein the biological tissue comprises skin tissue and adipose tissue.

12. The method of claim 1 , wherein the advancing of the first and second segments occur at the same time or at different times.

13. The method of claim 1 , wherein the raising of the first and second segments occur at the same time or at different times.

14. The method of claim 1 , wherein the advancing comprises firing a solenoid.

15. The method of claim 1 , wherein the two dimensional array comprises a circle.

16. The method of claim 15 , wherein the circle comprises an area of about one square inch.

17. The method of claim 1 , wherein the plurality of segments of hollow tubes comprises about 300 hollow tubes.

18. The method of claim 1 , further comprising, prior to the harvesting process, determining that the applied force meets or exceeds the predetermined force value.

19. The method of claim 1 , wherein generating an alert comprises outputting, via the device, at least one of an audible alert and a visual alert.

20. The method of claim 1 , wherein the predetermined force value is within the range of 10 to 40 pounds.

Assignments (7)
PATENT SECURITY AGREEMENT Recorded May 28, 2026
From: MEDLINE INDUSTRIES, LP
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT
Reel/Frame 075643/0462 →
PATENT SECURITY AGREEMENT Recorded Jun 20, 2025
From: MEDLINE INDUSTRIES, LP
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT
Reel/Frame 071672/0100 →
SECURITY INTEREST Recorded Oct 21, 2021
From: MEDLINE INDUSTRIES, LP
To: WILMINGTON TRUST, NATIONAL ASSOCIATION
Reel/Frame 057927/0091 →
SECURITY INTEREST Recorded Oct 21, 2021
From: MEDLINE INDUSTRIES, LP
To: BANK OF AMERICA, N.A.
Reel/Frame 058040/0001 →
CHANGE OF NAME Recorded Oct 14, 2021
From: MEDLINE INDUSTRIES, INC.
To: MEDLINE INDUSTRIES, LP
Reel/Frame 057807/0297 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 4, 2018
From: SEVENOAKS BIOSYSTEMS, LLC
To: MEDLINE INDUSTRIES, INC.
Reel/Frame 047067/0866 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 4, 2018
From: GUILES, MARVIN A; LABOMBARD, DENIS; SIDOTI, CHARLES; SABIR, SAMEER
To: SEVENOAKS BIOSYSTEMS, LLC
Reel/Frame 047191/0389 →