IP Library Granted Patent US 10,905,546
Granted Patent B1
US 10,905,546 · App. 16/122,741 · Granted Feb 2, 2021

Controlled unfolding of intraocular lenses

Inventors: Stein Kuiper (Pacifica, CA); Brooke Basinger (San Francisco, CA)
Assignee: Verily Life Sciences LLC
A61F2/1662A61F2002/1681A61F2210/0038A61F2250/0001
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Quick Facts
Patent No.
US 10,905,546
App. No.
16/122,741
Granted
Feb 2, 2021
Kind
B1
Abstract

A method for controlled unfolding of an intraocular lens (IOL) includes inserting a folded IOL into an eye and heating a shape memory alloy (SMA) ring included with the IOL to a temperature that is at least a transition temperature of the SMA ring. The transition temperature is above a body temperature. Heating the SMA ring causes the SMA ring to unfold the IOL.

Claims (44)

1. A method for the controlled unfolding of an intraocular lens (IOL), the method comprising:

inserting a folded IOL into an eye, wherein the IOL includes a shape memory alloy (SMA) ring having a transition temperature above a body temperature; and

heating the SMA ring to a temperature that is at least to the transition temperature, wherein the heating causes the SMA ring to unfold the IOL.

2. The method of claim 1 , wherein heating the SMA ring to a temperature that is at least the transition temperature includes:

inductively heating the SMA ring to at least the transition temperature.

3. The method of claim 2 , wherein the inductive heating is provided by an inductive coil.

4. The method of claim 2 , wherein the inductive heating is provided by a Helmholtz coil.

5. The method of claim 1 , further comprising:

monitoring the unfolding of the IOL during the heating of the SMA ring to determine a rate of unfolding; and

adjusting a rate of the heating of the SMA ring in response to the monitoring.

6. The method of claim 5 , wherein adjusting the heating of the SMA ring in response to the monitoring includes:

to increase the rate of the unfolding, increasing the rate of the heating.

7. The method of claim 6 , wherein adjusting the heating of the SMA ring in response to the monitoring includes:

to decrease the rate of unfolding being above a threshold, decreasing the rate of the heating.

8. The method of claim 1 , wherein the SMA ring is embedded in a support structure of the IOL.

9. The method of claim 1 , wherein the SMA ring is embedded in a sidewall of the IOL.

10. The method of claim 9 , wherein the SMA ring is an electrode of the IOL.

11. The method of claim 1 , wherein the SMA ring is an antenna of the IOL.

12. The method of claim 1 , further comprising:

folding the IOL into a desired geometry; and

loading the folded IOL into an inserter or injector for implantation.

13. The method of claim 12 , wherein the folding of the IOL is performed at a temperature below the transition temperature.

14. The method of claim 12 , wherein the folding of the IOL is performed at a temperature above the transition temperature.

15. The method of claim 1 , further comprising:

after unfolding the IOL, rinsing the IOL with a saline or viscoelastic gel; and

adjusting a position of the IOL in the eye.

16. The method of claim 1 , wherein heating the SMA ring includes:

heating the SMA ring from a starting transition temperature to a final transition temperature, wherein the SMA ring is completely unfolded when the temperature reaches the final transition temperature.

17. The method of claim 1 , wherein heating the SMA ring to a temperature that is at least the transition temperature includes:

heating the SMA ring to at least the transition temperature using one of laser pulses, ultrasound, or warm saline.

18. A method of unfolding an intraocular lens (IOL), the method comprising:

implanting a folded IOL into an eye, wherein the IOL includes a support structure and a shape memory alloy (SMA) ring included in the support structure, the SMA ring having a transition temperature above body temperature; and

inductively heating the SMA ring to a temperature that is at least to the transition temperature, wherein the heating causes the SMA ring to unfold the IOL.

19. The method of claim 18 , wherein inductively heating the SMA ring to a temperature that is at least to the transition temperature comprises:

inductively heating the SMA ring from a starting transition temperature to a final transition temperature, wherein the SMA ring is completely unfolded when the temperature reaches the final transition temperature.

20. The method of claim 18 , wherein the inductive heating is provided by an inductive coil.

21. The method of claim 18 , wherein the inductive heating is provided by a Helmholtz coil.

22. The method of claim 18 , further comprising:

monitoring the unfolding of the IOL during the heating of the SMA ring to determine a rate of unfolding; and

adjusting the heating of the SMA ring in response to the monitoring.

23. The method of claim 22 , wherein adjusting the heating of the SMA ring in response to the monitoring includes:

to increase the rate of unfolding, increasing the heating to increase a rate of unfolding.

24. The method of claim 22 , wherein adjusting the heating of the SMA ring in response to the monitoring includes:

to decrease the rate of unfolding, decreasing the heating to decrease a rate of unfolding.

Assignments (4)
CHANGE OF NAME Recorded Apr 1, 2026
From: VERILY LIFE SCIENCES LLC
To: VERILY HEALTH INC.
Reel/Frame 075367/0775 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 5, 2024
From: TWENTY TWENTY THERAPEUTICS LLC
To: VERILY LIFE SCIENCES LLC
Reel/Frame 068846/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 29, 2023
From: VERILY LIFE SCIENCES LLC
To: TWENTY TWENTY THERAPEUTICS LLC
Reel/Frame 064163/0186 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 12, 2018
From: KUIPER, STEIN; BASINGER, BROOKE
To: VERILY LIFE SCIENCES LLC
Reel/Frame 046851/0694 →
Cited By (1)
US 12,508,123