IP Library › Patent Application 16124122
Patent Application
App. No. 16/124,122

3-DESOXY DERIVATIVE AND PHARMACEUTICAL COMPOSITIONS THEREOF

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Quick Facts
Patent No.
US None
App. No.
16/124,122
Abstract

The present application provides Compound 1: or a pharmaceutically acceptable salt or amino acid conjugate thereof. The present invention relates to an FXR activator and to methods of making and using said compound.

Claims (7)

1 . A compound of structure:

or a pharmaceutically acceptable salt or amino acid conjugate thereof.

2 . The free acid of the compound of claim 1 .

3 . The pharmaceutically acceptable salt of the compound of claim 1 .

4 . The amino acid conjugate of the compound of claim 1 , wherein the amino acid is glycine or sarcosine.

5 . A pharmaceutical composition comprising the compound of claim 1 and a pharmaceutically acceptable carrier or excipient.

6 . A method for treating or preventing a disease or condition activated by FXR, comprising administering to a subject in need thereof an effective amount of a compound of claim 1 , wherein the disease or condition activated by FXR is selected from cardiovascular disease, chronic liver disease, lipid disorder, gastrointestinal disease, renal disease, metabolic disease, cancer, and neurological disease.