Heterocyclic compounds for the treatment of neurological and psychological disorders
View Patent ↗Lactam compounds of Formula I and their use for the treatment of neurological and psychiatric disorders including schizophrenia, bipolar disorder, anxiety disorder and insomnia is disclosed.
1. A compound having the formula:
or a pharmaceutically acceptable salt or solvate thereof.
2. A compound having the formula:
3. A pharmaceutical composition comprising the compound of claim 1 , and one or more pharmaceutically acceptable carriers or excipients.
4. A pharmaceutical composition comprising the compound of claim 2 , and one or more pharmaceutically acceptable carriers or excipients.
5. A method of treating schizophrenia comprising administering the compound of claim 1 to a patient in need thereof.
6. A method of treating bipolar disorder comprising administering the compound of claim 1 to a patient in need thereof.
7. A method of treating depression comprising administering the compound of claim 1 to a patient in need thereof.
8. A method of treating mania comprising administering the compound of claim 1 to a patient in need thereof.
9. A method of treating anxiety comprising administering the compound of claim 1 to a patient in need thereof.
10. A method of treating schizophrenia comprising administering a compound having the formula:
to a patient in need thereof.
11. A method of treating bipolar disorder comprising administering a compound having the formula:
to a patient in need thereof.
12. A method of treating depression comprising administering the compound of claim 2 to a patient in need thereof.
13. A method of treating mania comprising administering the compound of claim 2 to a patient in need thereof.
14. A method of treating anxiety comprising administering the compound of claim 2 to a patient in need thereof.
15. A method of treating schizophrenia comprising administering the pharmaceutical composition of claim 3 to a patient in need thereof.
16. A method of treating bipolar disorder comprising administering the pharmaceutical composition of claim 3 to a patient in need thereof.
17. A method of treating depression comprising administering the pharmaceutical composition of claim 3 to a patient in need thereof.
18. A method of treating mania comprising administering the pharmaceutical composition of claim 3 to a patient in need thereof.
19. A method of treating anxiety comprising administering the pharmaceutical composition of claim 3 to a patient in need thereof.
20. A method of treating schizophrenia comprising administering the pharmaceutical composition of claim 4 to a patient in need thereof.
21. A method of treating bipolar disorder comprising administering the pharmaceutical composition of claim 4 to a patient in need thereof.
22. A method of treating depression comprising administering the pharmaceutical composition of claim 4 to a patient in need thereof.
23. A method of treating mania comprising administering the pharmaceutical composition of claim 4 to a patient in need thereof.
24. A method of treating anxiety comprising administering the pharmaceutical composition of claim 4 to a patient in need thereof.