IP Library Granted Patent US 10,294,233
Granted Patent B2
US 10,294,233 · App. 16/136,314 · Granted May 21, 2019

Treatment of

Inventors: Vern L. Schramm (New Rochelle, NY); Keith Clinch (Lower Hutt, NZ); Shivali Ashwin Gulab (Wellington, NZ)
Assignees: Albert Einstein College of Medicine; Victoria Link Limited
C07D487/04A61K31/519A61P31/04C07D471/04Y02A50/471Y02A50/473Y02A50/475Y02A50/481
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Quick Facts
Patent No.
US 10,294,233
App. No.
16/136,314
Granted
May 21, 2019
Kind
B2
Abstract

Methods of treating infections due to Helicobacter pylori ( H. pylori ), in particular in subjects having a peptic ulcer, are disclosed where the methods comprise administering inhibitors of H. pylori MTAN (5′-methylthioadenosine nucleosidase) to the subject.

Claims (4)

1. A compound having the structure

or a pharmaceutically acceptable salt thereof, or an ester thereof.

2. A pharmaceutical composition comprising a pharmaceutically acceptable carrier and a compound having the structure

or a pharmaceutically acceptable salt thereof, or an ester thereof.

Assignments (1)
MERGER AND CHANGE OF NAME Recorded Feb 26, 2019
From: ALBERT EINSTEIN COLLEGE OF MEDICINE, INC.; ALBERT EINSTEIN COLLEGE OF MEDICINE
To: ALBERT EINSTEIN COLLEGE OF MEDICINE
Reel/Frame 048438/0275 →
Continuity (3)
Division 15118113
Provisional Application 61938755 · Feb 12, 2014
Related Publication 20190016730A1 · Jan 17, 2019