Devices systems and methods for evaluating blood flow with vascular perfusion imaging

1. A medical processing unit configured to:

receive a first set of perfusion imaging data corresponding to a first set of perfusion images from a perfusion imaging system configured to obtain perfusion imaging data associated with movement of contrast through a vessel of a patient;

determine, based on the first set of perfusion imaging data, a first group of at least two parameters representative of the movement of the contrast through the vessel of the patient, wherein the first group of at least two parameters comprises at least two of time to peak, wash in rate, area under curve, or mean transit time;

receive a different, second set of perfusion imaging data corresponding to a different, second set of perfusion images from the perfusion imaging system;

determine, based on the second set of perfusion imaging data, a second group of at least two parameters representative of the movement of the contrast through the vessel of the patient, wherein the second group of at least two parameters is the same as the first group of at least two parameters;

generate a single graphical representation for simultaneous display of the first set of perfusion imaging data, the first group of at least two parameters, the second set of perfusion imaging data, and the second group of at least two parameters; and

output the single graphical representation to a graphical user interface for display,

wherein the first set of perfusion imaging data comprises perfusion imaging data obtained prior to an intravascular procedure and the second set of perfusion imaging data comprises perfusion imaging data obtained after the intravascular procedure, and

wherein the single graphical representation comprises a combination of a first graphical representation for the first set of perfusion imaging data and the first group of at least two parameters and a second graphical representation for the second set of perfusion imaging data and the second group of at least two parameters.

2. The medical processing unit of claim 1 , wherein the single graphical representation comprises a first curve representative of the movement of the contrast through the vessel of the patient as shown in the first graphical representation and a second curve representative of the movement of the contrast through the vessel of the patient as shown in the second graphical representation, both plotted on the same set of axes.

3. The medical processing unit of claim 1 , further configured to generate a recommendation based on the first group of at least two parameters and to output the recommendation to the graphical user interface for display.

4. The medical processing unit of claim 3 , wherein the recommendation comprises identifying one or more candidate sites for the intravascular procedure.

5. A medical system, comprising:

the medical processing unit according to claim 1 ;

the graphical user interface; and

the perfusion imaging system.

6. The medical system of claim 5 , wherein the single graphical representation comprises:

a graph representative of the movement of the contrast through the vessel of the patient, wherein the graph comprises:

a first curve corresponding to the first set of perfusion imaging data; and

a different, second curve corresponding to the second set of perfusion imaging data;

a numerical representation of the first group of at least two parameters; and

a numerical representation of the second group of at least two parameters.

7. A method, comprising:

receiving, by a medical processing unit, a first set of perfusion imaging data corresponding to a first set of perfusion images from a perfusion imaging system configured to obtain perfusion imaging data associated with movement of contrast through a vessel of a patient;

determining, by the medical processing unit, based on the first set of perfusion imaging data, a first group of at least two parameters representative of the movement of the contrast through the vessel of the patient, wherein the first group of at least two parameters comprises at least two of time to peak, wash in rate, area under curve, or mean transit time;

receiving, by the medical processing unit, a different, second set of perfusion imaging data corresponding to a different, second set of perfusion images from the perfusion imaging system;

determining, by the medical processing unit, based on the second set of perfusion imaging data, a second group of at least two parameters representative of the movement of the contrast through the vessel of the patient, wherein the second group of at least two parameters is the same as the first group of at least two parameters;

generating, by the medical processing unit, a single graphical representation for simultaneous display of the first set of perfusion imaging data, the first group of at least two parameters, the second set of perfusion imaging data, and the second group of at least two parameters; and

outputting, from the medical processing unit, the single graphical representation to a graphical user interface for display,

wherein the first set of perfusion imaging data comprises perfusion imaging data obtained prior to an intravascular procedure and the second set of perfusion imaging data comprises perfusion imaging data obtained after the intravascular procedure,

wherein generating the single graphical representation comprises combining a first graphical representation of the first set of perfusion imaging data and the first group of at least two parameters and a second graphical representation of the second set of perfusion imaging data and the second group of at least two parameters.

8. The method of claim 7 , further comprising:

determining, by the medical processing unit, the difference between the first group of at least two parameters and the second group of at least two parameters; and

outputting, from the medical processing unit, the difference to the graphical user interface for display.

9. The method of claim 7 , wherein the single graphical representation comprises a first curve representative of the movement of the contrast through the vessel of the patient as shown in the first graphical representation and a second curve representative of the movement of the contrast through the vessel of the patient as shown in the second graphical representation both plotted on the same set of axes.

10. The medical processing unit of claim 1 , wherein the medical processing unit is further configured to receive a user selection of a region of interest.

11. The method of claim 7 , wherein the single graphical representation comprises:

a graph representative of the movement of the contrast through the vessel of the patient, wherein the graph comprises:

a first curve corresponding to the first set of perfusion imaging data; and

a different, second curve corresponding to the second set of perfusion imaging data;

a numerical representation of the first group of at least two parameters; and

a numerical representation of the second group of at least two parameters.

12. The method of claim 7 , further comprising:

generating, by the medical processing unit, a first perfusion image of an anatomical structure based on the first set of perfusion imaging data; and

outputting, from the medical processing unit, the first perfusion image to the graphical user interface for display.

13. The method of claim 12 , further comprising:

generating, by the medical processing unit, a second perfusion image of the anatomical structure based on the second set of perfusion imaging data; and

outputting, from the medical processing unit, the second perfusion image to the graphical user interface for display.

14. The method of claim 12 , further comprising:

generating, by the medical processing unit, a recommendation based on the first set of perfusion imaging data, wherein generating the recommendation comprises identifying one or more candidate sites for the intravascular procedure; and

outputting, from the medical processing unit, the recommendation to the graphical user interface for display.

15. The method of claim 14 , wherein identifying one or more candidate sites for the intravascular procedure comprises providing a visual indicator of the one or more candidate sites on the anatomical structure shown in the first perfusion image.

16. The medical processing unit of claim 1 , wherein the medical processing unit is further configured to:

determine, only responsive to receiving a user input, an additional parameter representative of the movement of the contrast through the vessel of the patient different than the first group of at least two parameters;

update, based on the additional parameter, the single graphical representation for simultaneous display of the first set of perfusion imaging data, the first group of at least two parameters, the second set of perfusion imaging data, the second group of at least two parameters, and the additional parameter; and

output the single graphical representation to the graphical user interface for display.

17. The medical processing unit of claim 1 , wherein the medical processing unit is further configured to:

generate a perfusion image based on a difference between an image of the first set of perfusion images and an image of the second set of perfusion images; and

output the perfusion image to the graphical user interface for display.