IP Library Granted Patent US 10,888,373
Granted Patent B2
US 10,888,373 · App. 16/155,814 · Granted Jan 12, 2021

Contact assessment between an ablation catheter and tissue

Inventors: Josef Vincent Koblish (Sunnyvale, CA); Donghoon Chun (Sunnyvale, CA); Jessi E. Johnson (Sunnyvale, CA)
Assignee: Epix Therapeutics, Inc.
A61B18/1492A61B5/0538A61B5/4836A61B5/6885A61B18/02A61B18/1206A61B90/06A61B5/01A61B5/042A61B18/1815A61B2018/00011A61B2018/00029A61B2018/00357A61B2018/00577A61B2018/00702A61B2018/00791A61B2018/00839A61B2018/00875A61B2018/00892A61B2018/00982A61B2018/126A61B2018/1417A61B2018/1467A61B2090/065A61B2218/002
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Quick Facts
Patent No.
US 10,888,373
App. No.
16/155,814
Filed
Oct 9, 2018
Granted
Jan 12, 2021
Kind
B2
Art Unit
3794
USPC
606/34
Abstract

Systems and methods for facilitating assessment of a nature of contact between an electrode assembly of an ablation catheter and viable body tissue are disclosed herein. In some embodiments, a method comprises obtaining a first detected voltage between a first electrode and a second electrode, wherein the first and second electrodes are positioned along an electrode assembly of the ablation catheter, and wherein the first electrode is distal to the second electrode, obtaining a second detected voltage between the second electrode and a third electrode, the third electrode positioned proximal to the second electrode.

Claims (34)

1. A method for facilitating contact assessment between an electrode assembly of an ablation catheter and viable body tissue, the method comprising:

obtaining a first detected voltage between a first electrode and a second electrode, wherein the first and second electrodes are positioned along an electrode assembly of the ablation catheter, and wherein the first electrode is distal to the second electrode;

obtaining a second detected voltage between the second electrode and a third electrode, the third electrode positioned proximal to the second electrode;

making a first comparison between the first detected voltage and a first threshold voltage, wherein the first threshold voltage is indicative of a level of contact between viable body tissue and a first portion of the ablation catheter, the first portion of the ablation catheter positioned at a location between the first and second electrodes; and

making a second comparison between the second detected voltage and a second threshold voltage, wherein the second threshold voltage is indicative of a level of contact between viable body tissue and a second portion of the ablation catheter, the second portion of the ablation catheter positioned at a location between the second and third electrodes;

the level of contact between viable body tissue and the first portion of the ablation catheter is determined by comparing the first voltage to the first threshold voltage;

the level of contact between viable body tissue and the second portion of the ablation catheter is determined by comparing the second voltage to the second threshold voltage;

displaying a variably sized halo around a graphical representation of the electrode assembly, a size and shape of the halo indicating the level and location of contact between the first electrode and the second electrode and viable tissue, the halo defining an enclosed boundary about at least a portion of the electrode assembly and being displayed on a plane parallel to longitudinal axis of the electrode assembly.

2. The method of claim 1 , wherein at least one of the first threshold voltage and the second threshold voltage is 0.30 mV.

3. The method of claim 1 , wherein the first threshold voltage is the same as the second threshold voltage.

4. The method of claim 1 , wherein at least one of the first threshold voltage and the second threshold voltage is between 0.2 mV and 0.4 mV.

5. The method of claim 1 , further comprising making a determination regarding the orientation of the electrode assembly relative to viable body tissue.

6. The method of claim 5 , wherein making a determination regarding the orientation of the electrode assembly relative to viable body tissue comprises contrasting the first comparison to the second comparison.

7. A method for facilitating contact assessment between an electrode assembly of an ablation catheter and viable body tissue, the method comprising:

obtaining a first detected voltage between a first electrode and a second electrode, the first electrode positioned adjacent the second electrode;

obtaining a second detected voltage between the second electrode and a third electrode, the third electrode positioned adjacent the second electrode, the second electrode located between the first electrode and the third electrode;

making a first comparison between the first detected voltage and a first threshold voltage, wherein the first threshold voltage is indicative of a level of contact between viable body tissue and a first portion of the ablation catheter, the first portion of the ablation catheter positioned at a location between the first and second electrodes; and

making a second comparison between the second detected voltage and a second threshold voltage, wherein the second threshold voltage is indicative of a level of contact between viable body tissue and a second portion of the ablation catheter, the second portion of the ablation catheter positioned at a location between the second and third electrodes;

the level of contact between viable body tissue and the first portion of the ablation catheter is determined by comparing the first voltage to the first threshold voltage; and

the level of contact between viable body tissue and the second portion of the ablation catheter is determined by comparing the second voltage to the second threshold voltage;

displaying a variably sized halo around a graphical representation of the electrode assembly, a size and shape of the halo indicating the level and location of contact between the first portion of the ablation catheter and the second portion of the ablation catheter and viable tissue, the halo defining an enclosed boundary about at least a portion of the electrode assembly and being displayed on a plane parallel to longitudinal axis of the electrode assembly.

8. The method of claim 7 , wherein at least one of the first threshold voltage and the second threshold voltage is between 0.2 mV and 0.4 mV.

9. The method of claim 7 , wherein the first threshold voltage is the same as the second threshold voltage.

10. The method of claim 7 , further comprising making a determination regarding the orientation of the electrode assembly relative to viable body tissue.

11. A method for facilitating contact assessment between an ablation assembly of an ablation catheter and viable body tissue, the method comprising:

obtaining a first detected voltage between a first ablation member and a second ablation member, the first ablation member positioned adjacent the second ablation member;

obtaining a second detected voltage between the second ablation member and a third ablation member, the third ablation member positioned adjacent the second electrode;

making a first comparison between the first detected voltage and a first threshold voltage, wherein the first threshold voltage is indicative of a level of contact between viable body tissue and a first portion of the ablation catheter, the first portion of the ablation catheter positioned at a location between the first and second ablation members; and

making a second comparison between the second detected voltage and a second threshold voltage, wherein the second threshold voltage is indicative of a level of contact between viable body tissue and a second portion of the ablation catheter, the second portion of the ablation catheter positioned at a location between the second and third ablation members;

contact between viable body tissue and the first portion of the ablation catheter is determined by comparing the first voltage to the first threshold voltage; and

contact between viable body tissue and the second portion of the ablation catheter is determined by comparing the second voltage to the second threshold voltage;

displaying a variably sized halo around a graphical representation of the ablation assembly, a size and shape of the halo indicating the level and location of contact between the first portion of the ablation catheter and the second portion of the ablation catheter and viable tissue, the halo defining an enclosed boundary about at least a portion of the ablation assembly and being displayed on a plane parallel to longitudinal axis of the electrode assembly.

12. The method of claim 11 , wherein the first threshold voltage is the same as the second threshold voltage.

13. The method of claim 11 , further comprising making a determination regarding the orientation of the ablation assembly relative to viable body tissue.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 10, 2018
From: KOBLISH, JOSEF VINCENT; CHUN, DONGHOON; JOHNSON, JESSI E.
To: EPIX THERAPEUTICS, INC.
Reel/Frame 047127/0297 →
Continuity (4)
Continuation PCTUS2018029639 · Apr 26, 2018
Provisional Application 62536616 · Jul 25, 2017
Provisional Application 62491082 · Apr 27, 2017
Related Publication 20190038348A1 · Feb 7, 2019
Cited By (8)
US 12,622,716 US 12,622,717 US 12,622,718 US 12,661,136 US 12,702,433 US 12,708,385 US 12,714,449 US 12,714,450