Image-based disease diagnostics using a mobile device
A diagnostic system performs disease diagnostic tests using at least an optical property modifying device and a mobile device. A user provides a biological sample from a patient to the optical property modifying device that reacts with a reagent in one or more reaction chambers of the device. The user captures one or more images of the one or more reaction chambers using an optical sensor of the mobile device. The diagnostic system can determine a quality level of the images based on factors such as skew, scale, focusing, shadowing, or white-balancing. Based on an analysis of the captured image, the diagnostic system can determine a test result of a disease diagnostic test for the patient. The diagnostic system may communicate the test result, as well as instructions for the disease diagnostic test, to the user via the mobile device.
1. A method for determining results for image-based diagnostic tests, the method comprising:
receiving one or more images of an optical property modifying device for a diagnostic test captured by an optical sensor of a mobile device, the optical property modifying device comprising a plurality of reaction chambers configured to perform a reaction between a biological sample and at least an optical property modifying reagent, wherein a surface of the optical property modifying device comprises an electronic display;
determining that the electronic display of the optical property modifying device is shown in the one or more images;
determining that an image of the set of one or more images shows a known geometric characteristic associated with the optical property modifying device;
determining one or more test results for the diagnostic test based at least in part on the image; and
providing the one or more test results for presentation by the mobile device.
2. The method of claim 1 , wherein the electronic display is a liquid crystal display.
3. The method of claim 1 , wherein the electronic display is an organic light emitting diode display.
4. The method of claim 1 , wherein the electronic display is an electronic paper display.
5. The method of claim 1 , wherein the electronic display comprises one or more light emitting diodes.
6. The method of claim 1 , further comprising providing a notification relating to the one or more test results on the mobile device via audio signals or tactile signals.
7. The method of claim 1 , wherein the reaction is a nucleic acid amplification assay, an immunoassay or enzyme-linked immunosorbent assays (ELISAs) that changes the properties of a solution that comprises the biological sample and the optical property modifying reagent in the reaction chambers.
8. The method of claim 1 , further comprising providing the one or more test results, a geographical location of the mobile device, and a timestamp of the geographical location to a computer server.
9. The method of claim 1 , further comprising generating a message comprising sponsored content based on the one or more test results and providing the message to the mobile device.
10. The method of claim 1 , further comprising providing information associated with the one or more test results to a pharmacy or healthcare provider.
11. The method of claim 1 , further comprising providing information obtained from the group consisting of: a Global Positioning System (GPS) sensor, a motion sensor, a proximity sensor, or a temperature sensor, on a mobile device.
12. The method of claim 1 , wherein a surface of the optical property modifying device comprises a machine-readable symbol that can be scanned to provide the mobile device or the user with information for the diagnostic test.
13. The method of claim 12 , wherein the machine-readable symbol is a QR code.
14. The method of claim 12 , wherein the machine-readable symbol is a bar code.
15. The method of claim 1 , further comprising determining that an image of the one or more images shows a known color characteristic associated with the optical property modifying device.
16. The method of claim 1 , further comprising determining the one or more test results in parallel or in series based at least in part on the image.
17. A computer program product comprising a non-transitory computer readable storage medium having instructions encoded thereon that, when executed by a processor, cause the processor to:
receive one or more images of an optical property modifying device for a diagnostic test captured by an optical sensor of a mobile device, the optical property modifying device comprising a plurality of reaction chambers configured to perform a reaction between a biological sample and at least an optical property modifying reagent, wherein a surface of the optical property modifying device comprises an electronic display;
determine that the electronic display of the optical property modifying device is shown in the one or more images;
determine that an image of the one or more images shows a known geometric characteristic associated with the optical property modifying device;
determine one or more test results for the diagnostic test based at least in part on the image; and
provide the one or more test results for presentation by the mobile device.
18. The computer program product of claim 17 , wherein the non-transitory computer readable storage medium further comprises instructions that when executed by the processor cause the processor to:
provide one or more notifications relating to the one or more test results on the mobile device via audio signals or tactile signals.
19. The computer program product of claim 17 , wherein the electronic display comprises one or more light emitting diodes.