IP Library Granted Patent US 10,729,351
Granted Patent B1
US 10,729,351 · App. 16/157,178 · Granted Aug 4, 2020

Artificial intelligence (AI) electrocardiogram (ECG)

Inventors: Guangren Chen (Arcadia, CA); Zhongnong Jiang (Richardson, TX)
A61B5/0468A61B5/044A61B5/0408A61B5/04017G06N20/00
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Quick Facts
Patent No.
US 10,729,351
App. No.
16/157,178
Granted
Aug 4, 2020
Kind
B1
Abstract

Electrical impulses are received from a beating heart. The electrical impulses are converted to an ECG waveform. The ECG waveform is converted to a frequency domain waveform, which, in turn, is separated into two or more different frequency domain waveforms, which, in turn, are converted into a plurality of time domain cardiac electrophysiological subwaveforms and discontinuity points between these subwaveforms. The plurality of subwaveforms and discontinuity points are compared to a database of subwaveforms and discontinuity points for normal and abnormal patients. An ST-T interval is identified from the plurality of subwaveforms and discontinuity points based on the comparison, the ST-T interval is divided into N number of equally spaced sections, and an average data value of detection is calculated for each section. A table is displayed that includes an average data value of detection for each section of the ST-T interval.

Claims (44)

1. A noninvasive electrocardiography (ECG) system for displaying quantitative indicators for an ST-T interval of an ECG waveform during measurement of the ECG waveform, comprising:

two or more electrodes adapted to be located near a beating heart of a patient and attached to the skin of the patient that receive electrical impulses from the beating heart;

a detector that detects the electrical impulses from at least one pair of electrodes of the two or more electrodes and converts the electrical impulses to an ECG waveform for each heartbeat of the beating heart;

a processor that

receives the ECG waveform for at least one heartbeat from the detector, converts the ECG waveform to a frequency domain waveform, separates the frequency domain waveform into two or more different frequency domain waveforms, and converts the two or more different frequency domain waveforms into a plurality of time domain cardiac electrophysiological subwaveforms and discontinuity points between these subwaveforms of the ECG waveform,

compares the plurality of subwaveforms and discontinuity points to a database of subwaveforms and discontinuity points for cardiac electrophysiological signals of ECG waveforms for a plurality of known and normal and abnormal patients, and

identifies an ST-T interval from the plurality of subwaveforms and discontinuity points based on the comparison, divides the ST-T interval into N number of equally spaced sections, and calculates an average data value of detection for each section; and

a display device that displays the ECG waveform for the at least one heartbeat of the beating heart and displays for the at least one heartbeat a table that includes an average data value of detection for each section of the ST-T interval.

2. The ECG system of claim 1 , wherein the processor separates the frequency domain waveform into two or more different frequency domain waveforms using one or more rectangular-shaped filters.

3. The ECG system of claim 2 , wherein the one or more rectangular-shaped filters comprise a finite-impulse-response (FIR) filter.

4. The ECG system of claim 2 , wherein the FIR filter comprises an interpolated FIR filter.

5. The ECG system of claim 1 , wherein the number N comprises 16.

6. The ECG system of claim 1 , wherein an average data value of detection above 0.10 with a variance of plus or minus 0.05 for a section is a normal value.

7. The ECG system of claim 6 , wherein an average data value of detection equal to or below 0.10 with a variance of plus or minus 0.05 for a section is an abnormal value.

8. The ECG system of claim 7 , wherein a normal value is displayed in black and an abnormal value is displayed in red.

9. The ECG system of claim 1 , wherein the processor further

identifies a first set of one or more subwaveforms or one or more discontinuity points representing an endocardium of the heart and a second set of one or more subwaveforms or one or more discontinuity points representing an epicardium of the heart and calculates an average positive potential for the first set and an average negative potential for the second set; and

a display device that displays the average positive potential for the endocardium and the average negative potential for the epicardium.

10. The ECG system of claim 1 , wherein the display device further displays a suspicious potential range and an abnormal potential range for the average positive potential for the endocardium and a suspicious potential range and an abnormal potential range for the average negative potential for the epicardium.

11. The ECG system of claim 1 , wherein the display device displays the average positive potential for the endocardium and the average negative potential for the epicardium for one or more electrodes of the two or more electrodes.

12. The ECG system of claim 1 , wherein the one or more electrodes include leads I, II, V3, V4, V5, and V6.

13. The ECG system of claim 1 , wherein

the processor further identifies a first set of one or more subwaveforms or one or more discontinuity points representing a right ventricle of the heart and a second set of one or more subwaveforms or one or more discontinuity points representing a left ventricle epicardium of the heart and calculates a first trajectory of myocardial action potential duration (APD) for the first set and a second trajectory of myocardial APD for the second set and;

the display device further displays the first trajectory for the right ventricle and the second trajectory for the left ventricle.

14. The ECG system of claim 13 , wherein the display device displays the first trajectory and the second trajectory in the form of a heart for normal values.

15. The ECG system of claim 13 , wherein the display device displays the first trajectory in blue and the second trajectory in red.

16. A method for displaying quantitative indicators for an ST-T interval of an ECG waveform during measurement of the ECG waveform, comprising:

receiving electrical impulses from a beating heart using two or more electrodes;

detecting the electrical impulses from at least one pair of electrodes of the two or more electrodes and converting the electrical impulses to an ECG waveform for each heartbeat of the beating heart using a detector;

receiving the ECG waveform for at least one heartbeat from the detector, converting the ECG waveform to a frequency domain waveform, separating the frequency domain waveform into two or more different frequency domain waveforms, and converting the two or more different frequency domain waveforms into a plurality of time domain cardiac electrophysiological subwaveforms and discontinuity points between these subwaveforms of the ECG waveform using a processor;

comparing the plurality of subwaveforms and discontinuity points to a database of subwaveforms and discontinuity points for cardiac electrophysiological signals of ECG waveforms for a plurality of known and normal and abnormal patients using the processor;

identifying an ST-T interval from the plurality of subwaveforms and discontinuity points based on the comparison, dividing the ST-T interval into N number of equally spaced sections, and calculating an average data value of detection for each section using the processor; and

displaying the ECG waveform for the at least one heartbeat of the beating heart and displaying for the at least one heartbeat a table that includes an average data value of detection for each section of the ST-T interval using the display device.

17. The method of claim 16 , wherein the number N comprises 16.

18. The method of claim 16 , wherein an average data value of detection above 0.10 with a variance of plus or minus 0.05 for a section is a normal value.

19. The method of claim 18 , wherein an average data value of detection equal to or below 0.10 with a variance of plus or minus 0.05 for a section is an abnormal value.

20. An invasive electrocardiography (ECG) system for displaying quantitative indicators for an ST-T interval of an ECG waveform during measurement of the ECG waveform, comprising:

two or more electrodes placed directly on the surface of a beating heart of a patient that receive electrical impulses from the beating heart;

a detector that detects the electrical impulses from at least one pair of electrodes of the two or more electrodes and converts the electrical impulses to an ECG waveform for each heartbeat of the beating heart;

a processor that

receives the ECG waveform for at least one heartbeat from the detector, converts the ECG waveform to a frequency domain waveform, separates the frequency domain waveform into two or more different frequency domain waveforms, and converts the two or more different frequency domain waveforms into a plurality of time domain cardiac electrophysiological subwaveforms and discontinuity points between these subwaveforms of the ECG waveform,

compares the plurality of subwaveforms and discontinuity points to a database of subwaveforms and discontinuity points for cardiac electrophysiological signals of ECG waveforms for a plurality of known and normal and abnormal patients, and

identifies an ST-T interval from the plurality of subwaveforms and discontinuity points based on the comparison, divides the ST-T interval into N number of equally spaced sections, and calculates an average data value of detection for each section; and

a display device that displays the ECG waveform for the at least one heartbeat of the beating heart and displays for the at least one heartbeat a table that includes an average data value of detection for each section of the ST-T interval.

Continuity (18)
Continuation In Part 16114025 · Aug 27, 2018
Continuation In Part 15998487 · Aug 16, 2018
Continuation In Part 15961952 · Apr 25, 2018
Continuation In Part 15904543 · Feb 26, 2018
Continuation In Part 15393135 · Dec 18, 2016
Continuation In Part 14749697 · Jun 25, 2015
Continuation In Part 14662996 · Mar 19, 2015
Continuation PCTUS2015020828 · Mar 16, 2015
Provisional Application 62701841 · Jul 23, 2018
Provisional Application 62571880 · Oct 11, 2017
Provisional Application 62551759 · Aug 27, 2017
Provisional Application 62546461 · Aug 16, 2017
Provisional Application 62489540 · Apr 25, 2017
Provisional Application 62463662 · Feb 26, 2017
Provisional Application 62271704 · Dec 28, 2015
Provisional Application 62271699 · Dec 28, 2015
Provisional Application 62017185 · Jun 25, 2014
Provisional Application 62008435 · Jun 5, 2014
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